Interleukin 17a antibody (FITC) (ABIN7205547) | 루미젠코리아
Antibodies-online
Human Mouse Rat Antibodies 100 tests
제품 사양
| Cat No | ABIN7205547 |
|---|---|
| Manufacturer | Antibodies-online |
| Reactivity | Human, Mouse, Rat |
| Target | Interleukin 17A,Interleukin 17A (IL-17A) is a proinflammatory cytokine produced by activated T cells. IL-17A-mediated downstream pathways induce the production of inflammatory molecules, chemokines, antimicrobial peptides, and remodeling proteins. It plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. It is the signature effector cytokine of Th17 cells, and in this role it primarily induces neutrophil activation and recruitment at infection and inflammatory sites. High levels of IL-17A are associated with rheumatoid arthritis, psoriasis, multiple sclerosis, and another inflammatory diseases, including lung injugy during severe COVID 19. This cytokine also contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. It is an effector cytokine for invariant NKT cells (iNKT), and it is involved in epithelial barrier formation upon injury.,Interleukin 17 |
| Size | 100 tests |
| Storage | 4 °C |
Datasheet PDF Provided by Antibodies-online
상세 설명
본 제품은 Th17 세포에서 분비되는 주요 전염증성 사이토카인인 IL-17A를 특이적으로 표적하는 FITC 결합 항체입니다. 유세포 분석(FACS) 및 면역형광 염색을 통해 염증성 질환이나 자가면역 반응 연구 시 관련 면역 세포의 활성도를 정밀하게 측정할 수 있습니다.
This FITC-conjugated monoclonal antibody specifically binds to IL-17A in human and mouse samples, facilitating the detection of Th17 cell populations via flow cytometry and immunofluorescence assays.
Interleukin 17a antibody (FITC) (ABIN7205547)은 루미젠코리아를 통해 국내 구매 및 견적이 가능합니다.
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –