CD3 antibody (PE) (ABIN94062) | 루미젠코리아
Antibodies-online
Human Antibodies 100 tests
제품 사양
| Cat No | ABIN94062 |
|---|---|
| Manufacturer | Antibodies-online |
| Reactivity | Human |
| Target | CD3 antigen, epsilon polypeptide,CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkynje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.,CD3E, T3E, TCRE |
| Size | 100 tests |
| Storage | 4 °C |
Datasheet PDF Provided by Antibodies-online
상세 설명
Human CD3 항원을 선택적으로 인식하는 PE 형광 표지 항체로, 유세포 분석(Flow Cytometry)을 통한 T 세포 분리 및 동정에 최적화된 제품입니다. TCR 복합체의 핵심 구성 요소인 CD3 epsilon 체인을 표적하여 T 세포 활성화 및 증식 연구에 필수적인 데이터를 제공합니다.
This PE-conjugated monoclonal antibody specifically targets the human CD3 epsilon subunit, serving as a robust marker for T-cell identification and subset analysis in flow cytometry applications.
타겟 유전자 정보 — T cell receptor alpha variable 6-3
이 유전자는 인간 TRAV9-2 (T 세포 수용체 알파 가변 9-2)의 상동 유전자입니다.
출처: NCBI Gene Database
CD3 antibody (PE) (ABIN94062)은 루미젠코리아를 통해 국내 구매 및 견적이 가능합니다.
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –