CD4 antibody (AA 385-457) (ABIN671376) | 루미젠코리아
Antibodies-online
Chicken Human Mouse Pig Rat Immunohistochemistry Antibodies 100 μL -20°C
제품 사양
| Cat No | ABIN671376 |
|---|---|
| Manufacturer | Antibodies-online |
| Reactivity | Chicken, Human, Mouse, Pig, Rat |
| Target | Synonyms: T-cell surface glycoprotein CD4, Cd4, T-cell surface antigen T4/Leu-3, W3/25 antigenBackground: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. |
| Assay Method | Immunohistochemistry |
| Size | 100 μL |
| Storage | -20°C |
Datasheet PDF Provided by Antibodies-online
상세 설명
이 항체는 T 세포 및 대식세포 표면의 CD4 당단백질을 표적으로 하며, 인간, 마우스, 돼지 등 다양한 종의 면역 기전 연구에 활용됩니다. 면역조직화학(IHC) 분석에 최적화되어 조직 내 T-helper 세포의 분포와 활성화 상태를 정밀하게 관찰할 수 있습니다.
This antibody targets the CD4 surface glycoprotein in multiple species including Human and Mouse, providing a robust tool for characterizing T-cell subsets via immunohistochemistry.
타겟 유전자 정보 — T cell receptor alpha variable 6-3
이 유전자는 인간 TRAV9-2 (T 세포 수용체 알파 가변 9-2)의 상동 유전자입니다.
출처: NCBI Gene Database
CD4 antibody (AA 385-457) (ABIN671376)은 루미젠코리아를 통해 국내 구매 및 견적이 가능합니다.
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C,-20 °C | 배송 조건: –
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C,-20 °C | 배송 조건: –