CD3 antibody (APC) (ABIN94063) | 루미젠코리아
Antibodies-online
Human Antibodies 100 tests
제품 사양
| Cat No | ABIN94063 |
|---|---|
| Manufacturer | Antibodies-online |
| Reactivity | Human |
| Target | CD3 antigen, epsilon polypeptide,CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkynje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.,CD3E, T3E, TCRE |
| Size | 100 tests |
| Storage | 4 °C |
Datasheet PDF Provided by Antibodies-online
상세 설명
본 제품은 인간 T세포 표면의 CD3 복합체를 표적하는 APC 형광 접합 항체로, 유세포 분석을 통해 T세포를 정밀하게 식별하고 분석하는 데 사용됩니다. B세포나 NK세포에는 발현되지 않는 T세포 특이적 마커로서 면역학 및 종양 연구 분야에서 높은 신뢰도를 제공합니다.
This APC-conjugated monoclonal antibody targets the human CD3 epsilon subunit for the precise identification and quantification of T-cell populations in diverse immunological research applications.
타겟 유전자 정보 — T cell receptor alpha variable 6-3
이 유전자는 인간 TRAV9-2 (T 세포 수용체 알파 가변 9-2)의 상동 유전자입니다.
출처: NCBI Gene Database
CD3 antibody (APC) (ABIN94063)은 루미젠코리아를 통해 국내 구매 및 견적이 가능합니다.
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –
제조사: Antibodies-online | 분류: Antibodies
보관 조건: 4 °C | 배송 조건: –