YY1 — 카탈로그 55건
Gene YY1
NCBI Gene 7528
취급 제조사 4곳
국내 소싱 가능
55건
유전자 개요
YY1은 징크핑거(zinc finger) 단백질의 GLI-Kruppel 계열에 속하며 거의 모든 조직에 보편적으로 분포하는 전사인자(transcription factor)이다. 다양한 프로모터(promoter)의 발현을 억제하기도 하고 활성화하기도 한다. 프로모터를 활성화하거나 억제하기 위해 히스톤 탈아세틸화효소(histone deacetylase)와 히스톤 아세틸전이효소(histone acetyltransferase)를 해당 프로모터로 끌어들일 수 있어, 그 기능에 히스톤 변형(histone modification)이 관여함을 시사한다.
Activation of anterior HOX genes in hindbrain development during early embryogenesisDNA Damage Recognition in GG-NEREstrogen-dependent gene expressionTFAP2 (AP-2) family regulates transcription of growth factors and their receptorsUCH proteinases
Gabriele de Vries syndromeIntellectual disabilitygenetic disordertriglyceride measurementglomerular filtration ratecystatin C measurementintellectual disability, autosomal dominant 40complex neurodevelopmental disorder
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) YY1 Is a Structural Regulator of Enhancer-Promoter Loops. · Cell (2017)GATA1 and YY1 are developmental repressors of the human epsilon-globin gene. · EMBO J (1995)YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression. · Nat Chem Biol (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109645-01 | CSB-RA026297A0HU | YY1 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA | 50μl, 100μl | |
| MyBioSource | R247-213903-01 | MBS9608537 | YY1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; ELISA | 0.1 mL | |
| Cloud-Clone | T813-115016-01 | MAF572Hu21 | Monoclonal Antibody to YY1 Transcription Factor (YY1) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-126467-01 | PAF572Hu01 | Polyclonal Antibody to YY1 Transcription Factor (YY1) | Rabbit | Polyclonal | Human | WB; ICC/IF | 100µl | |
| MyBioSource | R247-147690-01 | MBS3223042 | YY1, Polyclonal Antibody | Rabbit | Polyclonal | Human | WB | 0.1 mL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
EGFR
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
VEGFA
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
ERBB2
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
TGFA
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
CGA
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
ESR1
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
ACTB
DNA Damage Recognition in GG-NER
UBB
DNA Damage Recognition in GG-NER