WNT5A — 카탈로그 33건

Gene WNT5A NCBI Gene 7474

취급 제조사 5곳

Cloud-Clone Biosynth MyBioSource Cusabio Abnova

국내 소싱 가능

33건

유전자 개요

WNT 유전자 가족(WNT gene family)은 분비형 신호 전달 단백질(secreted signaling proteins)을 암호화하는 구조적으로 관련된 유전자들로, WNT5A는 정상적(canonical) 및 비정상적(non-canonical) WNT 경로를 통해 신호를 전달하는 구성원이다. 이 단백질은 7회 횡단 수용체(seven transmembrane receptor)인 frizzled-5와 티로신 키나아제(tyrosine kinase) 고아 수용체(orphan receptor) 2의 리간드(ligand)로, 배아 발생(embryogenesis) 동안 발생 경로를 조절하고 종양 발생(oncogenesis)에도 관여할 수 있다. 이 유전자의 돌연변이는 상염색체 우성 로비노 증후군(Robinow syndrome)의 원인이며, 선택적 스플라이싱(alternative splicing)에 의해 여러 전사 변이체(transcript variants)가 만들어진다.

Asymmetric localization of PCP proteinsCa2+ pathwayCargo recognition for clathrin-mediated endocytosisClass B/2 (Secretin family receptors)Clathrin-mediated endocytosisNegative regulation of TCF-dependent signaling by WNT ligand antagonistsPCP/CE pathwayTCF dependent signaling in response to WNTWNT ligand biogenesis and traffickingWNT5:FZD7-mediated leishmania damping

Robinow syndromeautosomal dominant Robinow syndromebody heightlean body masssitting height measurementbody composition measurementwhole body water massbase metabolic rate measurement

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression. · Cell Commun Signal (2020)FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts. · Theranostics (2021)Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes. · Osteoarthritis Cartilage (2017)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cloud-Clone	T813-110920-01	LAP549Mu81	FITC-Linked Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rabbit	Antibody labeling	Murine	WB; IHC; ICC; IF.	100µl
Biosynth	F502-103300-01	10R-1911	WNT5A antibody	Mouse	Monoclonal	Human	ELISA, IHC, WB	100 ul
Biosynth	F502-103433-01	10R-2049	WNT5A antibody	Mouse	Monoclonal	Human	ELISA, IF, IHC, WB	100 ul
Cloud-Clone	T813-115892-01	MAP549Hu21	Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-128397-01	PAP549Ra01	Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rabbit	Polyclonal	Rat	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-115893-01	MAP549Ra21	Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Mouse	Monoclonal	Rat	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-128394-01	PAP549Hu01	Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rabbit	Polyclonal	Human	Testing in progress	100µl
Cloud-Clone	T813-128395-01	PAP549Mu01	Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rabbit	Polyclonal	Murine	WB	100µl
Cloud-Clone	T813-128396-01	PAP549Mu02	Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rabbit	Polyclonal	Murine	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-156609-01	MBS533020	WNT5A, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; IHC; WB	0.1 mL
MyBioSource	R247-146480-01	MBS3200765	WNT5A, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Zebrafish, Horse	WB; IHC	0.1 mL
MyBioSource	R247-132535-01	MBS2111713	Wingless Type MMTV Integration Site Family, Member 5A (WNT5A), Monoclonal Antibody	Mouse	Monoclonal	Mouse	WB; IHC; ICC; IP	0.1 mL
MyBioSource	R247-199619-01	MBS9132577	WNT5A, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	WB	0.02 mL
Biosynth	F502-138107-01	70R-6956	WNT5A antibody	Rabbit	Polyclonal	WNT5A antibody was raised against the middle region of WNT5A; Cross: Human,Mouse,Rat	WB	100 ul

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cloud-Clone	T813-107293-01	KSP549Hu01	ELISA Kit DIY Materials for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Human	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	0.059ng/mL	96T*10
Cloud-Clone	T813-107294-01	KSP549Mu01	ELISA Kit DIY Materials for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Murine	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	0.059ng/mL	96T*10
Cloud-Clone	T813-107295-01	KSP549Ra01	ELISA Kit DIY Materials for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rat	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	0.059ng/mL	96T*10
Cusabio	T094-103846-01	CSB-EL026138MO	Mouse Protein Wnt-5a(WNT5A) ELISA kit	Mus musculus (Mouse)	ELISA	serum, plasma, cell culture supernates, tissue homogenates	0.78 pg/mL	96T,5×96T,10×96T
Cusabio	T094-103845-01	CSB-EL026138HU	Human Protein Wnt-5a(WNT5A) ELISA kit	Homo sapiens (Human)	ELISA	serum, plasma, tissue homogenates	0.039 ng/mL	96T,5×96T,10×96T
MyBioSource	R247-153397-01	MBS453865	Wingless Type MMTV Integration Site Family, Member 5A (WNT5A), ELISA Kit	Mouse	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	12.4pg/mL	48 Tests
MyBioSource	R247-204027-01	MBS932852	wingless-type MMTV integration site family, member 5A (WNT5A), ELISA Kit	Mouse	ELISA	Serum, plasma, cell culture supernates, tissue homogenates	The minimum detectable dose of mouse WNT5A is typically less than 0.78 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.	24-Strip-Wells
Cloud-Clone	T813-149419-01	SEP549Mi	ELISA Kit for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Monkey	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.061ng/mL.	96T
Cloud-Clone	T813-149421-01	SEP549Ra	ELISA Kit for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Rat	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.054ng/mL.	96T
Cloud-Clone	T813-149418-01	SEP549Hu	ELISA Kit for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Human	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.061ng/mL.	96T
Cloud-Clone	T813-149420-01	SEP549Mu	ELISA Kit for Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	Murine	ELISA	serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.056ng/mL.	96T

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Cloud-Clone	T813-141658-01	RPP549Ra01	Recombinant Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	E.coli	Rat	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-141656-01	RPP549Mu01	Recombinant Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-141655-01	RPP549Hu01	Recombinant Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-100615-01	APP549Ra01	Active Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)		Rat	Cell culture; Activity Assays.	50µg
Cloud-Clone	T813-100614-01	APP549Mu01	Active Wingless Type MMTV Integration Site Family, Member 5A (WNT5A)		Murine	Cell culture; Activity Assays.	50µg
Abnova	U731-104400-01	H00007474-Q01	WNT5A (Human) Recombinant Protein (Q01)	Wheat Germ (in vitro)	Human	AP,Array,WB-Re,ELISA
Abnova	U731-104399-01	H00007474-P01	WNT5A (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,WB-Re,ELISA

WNT5A — 카탈로그 33건

유전자 개요

관련 표적