VASP — 카탈로그 40건
Gene VASP
NCBI Gene 7408
국내 소싱 가능
40건
유전자 개요
혈관확장제 자극 인단백질(VASP)은 Ena-VASP 단백질 계열의 구성원이다. Ena-VASP 계열 단백질들은 E/DFPPPPXD/E 모티프를 포함하는 단백질과 결합하는 N-말단 EHV1 도메인을 포함하며, Ena-VASP 단백질을 국소 접착(focal adhesions)으로 표적화한다. 단백질의 중간 부위에는 SH3 및 WW 도메인을 포함하는 단백질과 결합하는 프롤린 풍부 도메인이 있다. C-말단 EVH2 도메인은 사량체화(tetramerization)를 매개하고 G-액틴(G actin)과 F-액틴(F actin) 모두와 결합한다. VASP는 필라멘트 액틴 형성과 관련이 있으며 세포 부착 및 이동에서 광범위한 역할을 할 것으로 보인다. VASP는 인테그린-세포외 기질 상호작용을 조절하는 세포 내 신호 전달 경로에도 관여할 수 있다. VASP는 고리형 뉴클레오타이드 의존성 키나아제(kinase)인 PKA와 PKG에 의해 조절된다.
Cell-extracellular matrix interactionsGeneration of second messenger moleculesSignaling by ROBO receptors
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데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Hypoxia-induced up-regulation of VASP promotes invasiveness and metastasis of hepatocellular carcinoma. · Theranostics (2018)New insights into Fat cadherins. · J Cell Sci (2005)The palladin/myotilin/myopalladin family of actin-associated scaffolds. · Int Rev Cytol (2005)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Enzo Life Sciences | R365-100801-01 | ALX-210-880-C025 | VASP polyclonal antibody (affinity purified) | Rabbit | Polyclonal | Human, Mouse, Porcine | ICC, IP, WB | 25 µg | |
| Enzo Life Sciences | R365-101676-01 | ALX-804-177-C050 | VASP monoclonal antibody (IE273) | Mouse | Monoclonal | Bovine, Human, Porcine, Rabbit | ICC, IP, WB | 50 µg | |
| MyBioSource | R247-215064-01 | MBS9614405 | VASP, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Dog, Pig, Sheep, Horse | WB; IF; ICC; EIA | 0.05 mL | |
| MyBioSource | R247-212297-01 | MBS9601106 | VASP, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-106047-01 | 10R-6261 | VASP antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, WB | 100 ul | |
| Biosynth | F502-134986-01 | 70R-50534 | VASP antibody | Rabbit | Polyclonal | Recognizes endogenous levels of VASP protein; Cross: Rat, Bovine, Dog | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-132194-01 | 70R-37281 | VASP antibody (Ser157) | Rabbit | Polyclonal | VASP antibody (Ser157) detects endogenous levels of VASP only when phosphorylated at serine 157. The antibody will detect species specific phosphorylation as follows: Human: Ser157 or Ser156, Mouse: Ser152, Rat: Ser154; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-130013-01 | 70R-34661 | VASP antibody | Rabbit | Polyclonal | VASP antibody detects endogenous levels of total VASP protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-106046-01 | 10R-6259 | VASP antibody | Mouse | Monoclonal | Human; Cross: Human, Rat | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-126527-01 | 70R-31071 | VASP antibody | Rabbit | Polyclonal | VASP antibody detects endogenous levels of total VASP protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-106048-01 | 10R-6262 | VASP antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, WB | 100 ul | |
| Biosynth | F502-106694-01 | 10R-7236 | VASP antibody | Mouse | Monoclonal | Human; Cross: Human, Dog | IHC, WB | 100 ul | |
| Biosynth | F502-115163-01 | 70R-10267 | VASP antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse | WB | 100 ul | |
| Biosynth | F502-132143-01 | 70R-37235 | VASP antibody (Ser238) | Rabbit | Polyclonal | VASP antibody (Ser238) detects endogenous levels of VASP only when phosphorylated at serine 238; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-126526-01 | 70R-31070 | VASP antibody (Ser157) | Rabbit | Polyclonal | VASP antibody detects endogenous levels of VASP only when phosphorylated at Ser157; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128146-01 | 70R-32560 | VASP antibody (Ser238) | Rabbit | Polyclonal | VASP antibody detects endogenous levels of VASP only when phosphorylated at serine 238; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-134985-01 | 70R-50533 | VASP antibody | Rabbit | Polyclonal | Recognizes endogenous levels of VASP protein; Cross: Monkey | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-128144-01 | 70R-32559 | VASP antibody (Ser157) | Rabbit | Polyclonal | VASP antibody detects endogenous levels of VASP only when phosphorylated at serine 157; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-115164-01 | 70R-10268 | VASP antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast | WB | 100 ul | |
| Biosynth | F502-124535-01 | 70R-21241 | VASP antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, IF, WB | 50 ul | |
| Cloud-Clone | T813-114101-01 | MAC603Hu22 | Monoclonal Antibody to Vasodilator Stimulated Phosphoprotein (VASP) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-123974-01 | PAC603Hu01 | Polyclonal Antibody to Vasodilator Stimulated Phosphoprotein (VASP) | Rabbit | Polyclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-114102-01 | MAC603Ra21 | Monoclonal Antibody to Vasodilator Stimulated Phosphoprotein (VASP) | Mouse | Monoclonal | Rat | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-123975-01 | PAC603Ra01 | Polyclonal Antibody to Vasodilator Stimulated Phosphoprotein (VASP) | Rabbit | Polyclonal | Rat | WB; IHC; ICC; IP. | 100µl | |
| MyBioSource | R247-190747-01 | MBS821571 | VASP, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rat, Bovine, Dog | WB; IHC; IF; ICC | 0.03 mL | |
| Biosynth | F502-108870-01 | 20R-2056 | VASP antibody | Rabbit | Human; Cross: Human, Mouse | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109175-01 | 20R-2370 | VASP antibody | Rabbit | Human; Cross: Human, Rat | IF, WB | 0.05 mg | ||
| Biosynth | F502-109144-01 | 20R-2339 | VASP antibody | Rabbit | Human; Cross: Human, Mouse | WB | 0.05 mg | ||
| Biosynth | F502-108822-01 | 20R-2008 | VASP antibody | Rabbit | Human; Cross: Human, Mouse | IHC, WB | 0.05 mg | ||
| Biosynth | F502-136233-01 | 70R-51671 | VASP antibody | Rabbit | Polyclonal | Recognizes endogenous levels of VASP protein | WB, IHC, IP | 100 ul | |
| ELK Biotechnology | T376-116733-01 | ES1414 | VASP (phospho Ser157) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat;Monkey | WB;IHC;IF;ELISA | 50μL | |
| MyBioSource | R247-196113-01 | MBS856923 | VASP, Antibody | Human, Mouse, Rat | WB; IHC | 0.05 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
ACTB
Cell-extracellular matrix interactions
FLNA
Cell-extracellular matrix interactions
ILK
Cell-extracellular matrix interactions
LIMS1
Cell-extracellular matrix interactions
CXCR4
Signaling by ROBO receptors
NRP1
Signaling by ROBO receptors
GPC1
Signaling by ROBO receptors
ROBO1
Signaling by ROBO receptors