UNG — 카탈로그 17건
Gene UNG
NCBI Gene 7374
취급 제조사 4곳
국내 소싱 가능
17건
유전자 개요
이 유전자는 여러 종류의 우라실-DNA 글리코실레이즈(uracil-DNA glycosylase) 중 하나를 지정한다. 우라실-DNA 글리코실레이즈의 한 가지 중요한 기능은 N-글리코실 결합을 끊어 DNA 분자에서 우라실을 제거하고 염기 절제 복구(base-excision repair, BER) 경로를 개시함으로써 돌연변이 발생을 막는 것이다. 우라실 염기는 시토신 탈아미노화 또는 dUMP 잔기 잘못 포함으로 인해 발생한다. 이 유전자의 대체 프로모터(promoter) 사용과 스플라이싱은 두 가지 다른 아이소폼, 즉 미토콘드리아 UNG1과 핵 UNG2를 생성한다.
Chromatin modifications during the maternal to zygotic transition (MZT)Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1Recognition and association of DNA glycosylase with site containing an affected pyrimidine
hyper-IgM syndrome type 5eosinophil countlevel of Rap guanine nucleotide exchange factor 1 in blood serumhigh density lipoprotein cholesterol measurementmean corpuscular hemoglobinerythrocyte volumefood allergymonocyte count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. · Sci Adv (2017)Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. · Biochemistry (1995)Mechanisms of APOBEC3 mutagenesis in human cancer cells. · Nature (2022)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-106030-01 | 10R-6232 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human | IF, WB | 100 ul | |
| Biosynth | F502-106032-01 | 10R-6236 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human | IF, IHC, WB | 100 ul | |
| Biosynth | F502-106031-01 | 10R-6234 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human | IF, IHC, WB | 100 ul | |
| Biosynth | F502-102450-01 | 10R-1054 | UNG antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user. | ELISA, WB | 100 ul | |
| Biosynth | F502-106693-01 | 10R-7235 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human | WB | 100 ul | |
| Biosynth | F502-106033-01 | 10R-6237 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human, Monkey | IHC, WB | 100 ul | |
| Biosynth | F502-106692-01 | 10R-7233 | UNG antibody | Mouse | Monoclonal | Human; Cross: Human | IHC, FC, WB | 100 ul | |
| Biosynth | F502-115162-01 | 70R-10266 | UNG antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish | WB | 100 ul | |
| Biosynth | F502-127092-01 | 70R-31591 | UNG antibody | Rabbit | Polyclonal | UNG antibody detects endogenous levels of total UNG protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-124458-01 | 70R-21171 | UNG antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Cloud-Clone | T813-115287-01 | MAG917Hu21 | Monoclonal Antibody to Uracil DNA Glycosylase (UNG) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-127037-01 | PAG917Hu01 | Polyclonal Antibody to Uracil DNA Glycosylase (UNG) | Rabbit | Polyclonal | Human | WB; IHC; ICC/IF | 100µl | |
| MyBioSource | R247-122918-01 | MBS1753453 | UNG, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Monkey | WB; IHC-P; ICC; IF; FC/FACS/FCM; EIA | 0.01 mg | |
| MyBioSource | R247-115790-01 | MBS140334 | Uracil DNA Glycosilase (UNG), Monoclonal Antibody | Mouse | Monoclonal | ELISA; WB | 0.005 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
OGG1
Displacement of DNA glycosylase by APEX1
TDG
Displacement of DNA glycosylase by APEX1
APEX1
Displacement of DNA glycosylase by APEX1
MUTYH
Displacement of DNA glycosylase by APEX1
MPG
Displacement of DNA glycosylase by APEX1
ACD
Cleavage of the damaged pyrimidine POT1
Cleavage of the damaged pyrimidine TERF1
Cleavage of the damaged pyrimidine