UBE2L3 — 카탈로그 15건
Gene UBE2L3
NCBI Gene 7332
국내 소싱 가능
15건
유전자 개요
유비퀴틴(ubiquitin)을 이용한 단백질 변형은 비정상적이거나 수명이 짧은 단백질을 분해하도록 표적화하는 중요한 세포 기작입니다. 유비퀴틴화(ubiquitination)는 최소 세 종류의 효소(E1, E2, E3)를 포함합니다. 이 유전자는 E2 유비퀴틴 결합 효소 계열의 구성원을 암호화합니다. 이 효소는 시험관 내에서 p53, c-Fos, 그리고 NF-kB 전구체 p105의 유비퀴틴화에 참여하는 것으로 입증되었습니다. 이 유전자에 대해 몇 가지 대체 스플라이싱 전사체 변이체가 발견되었습니다.
Antigen processing: Ubiquitination & Proteasome degradationE3 ubiquitin ligases ubiquitinate target proteinsPINK1-PRKN Mediated MitophagyRegulation of TNFR1 signalingRegulation of necroptotic cell deathSynthesis of active ubiquitin: roles of E1 and E2 enzymes
neurodegenerative diseaseerythrocyte volumemean corpuscular hemoglobin concentrationlymphocyte counttotal cholesterol measurementhigh density lipoprotein cholesterol measurementneutrophil percentage of leukocyteslymphocyte percentage of leukocytes
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Ubiquitin is phosphorylated by PINK1 to activate parkin. · Nature (2014)Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. · Nature (2021)USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy. · Autophagy (2020)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-107272-01 | CSB-PA025463LA01HU | UBE2L3 Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC, IF | 50μg, 100μg | |
| MyBioSource | R247-213900-01 | MBS9608510 | UBE2L3, Polyclonal Antibody | Rabbit | Polyclonal | Human | WB; ELISA | 0.1 mL | |
| Biosynth | F502-115349-01 | 70R-1044 | UBE2L3 antibody | Rabbit | Polyclonal | UBE2L3 antibody was raised against the C terminal of UBE2L3; Cross: Human | WB, IHC | 100 ul | |
| Biosynth | F502-125652-01 | 70R-2746 | UBE2L3 antibody | Rabbit | Polyclonal | UBE2L3 antibody was raised against the middle region of UBE2L3; Cross: Human,Mouse | WB | 100 ul | |
| Biosynth | F502-124388-01 | 70R-21108 | UBE2L3 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-126285-01 | 70R-3085 | UBE2L3 antibody | Rabbit | Polyclonal | UBE2L3 antibody was raised against the C terminal of UBE2L3; Cross: Human, Mouse, Rat, Dog | WB | 100 ul | |
| Biosynth | F502-116162-01 | 70R-12834 | UBE2L3 antibody | Rabbit | Polyclonal | Human | IF, ICC, IHC-P, WB | 100 ul | |
| Cloud-Clone | T813-114798-01 | MAE602Hu21 | Monoclonal Antibody to Ubiquitin Conjugating Enzyme E2L3 (UBE2L3) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-125908-01 | PAE602Hu01 | KO-Validated Polyclonal Antibody to Ubiquitin Conjugating Enzyme E2L3 (UBE2L3) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| MyBioSource | R247-150066-01 | MBS420751 | UBE2L3, Polyclonal Antibody | Goat | Polyclonal | Human, Mouse, Rat, Pig | EIA; WB | 0.1 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
UBB
Regulation of necroptotic cell death
UBE2D2
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
UBE2D1
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
RIPK1
Regulation of necroptotic cell death
CASP8
Regulation of necroptotic cell death
TRADD
Regulation of necroptotic cell death
XIAP
Regulation of necroptotic cell death
FADD
Regulation of necroptotic cell death