TYROBP (TYROBP) — 카탈로그 25건

이 유전자는 세포막을 가로지르는 폴리펩타이드(polypeptide)를 암호화하며, 세포질 부위에 면역수용체 티로신 기반 활성화 모티프(immunoreceptor tyrosine-based activation motif, ITAM)를 포함합니다. 암호화된 단백질은 막 당단백질(membrane glycoprotein) 계열인 킬러 세포 억제 수용체(killer-cell inhibitory receptor, KIR)와 결합할 수 있으며, 활성 신호 전달 요소로 작용할 수 있습니다. 이 단백질은 제타-사슬(TCR) 관련 키나아제 70kDa(zeta-chain (TCR) associated protein kinase 70kDa, ZAP-70) 및 비장 티로신 키나아제(spleen tyrosine kinase, SYK)와 결합하여 신호 전달, 뼈 형성, 뇌 수초화, 염증(inflammation) 과정에 관여할 수 있습니다. 이 유전자 내 돌연변이는 골지형 다낭성 골이형성증과 경화성 백질뇌병증(polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy, PLOSL), 즉 나수-하코라병(Nasu-Hakola disease)과 관련이 있습니다. 이 유전자의 추정 수용체(receptor)인 골수 세포에서 발현되는 트리거 수용체 2(triggering receptor expressed on myeloid cells 2, TREM2) 또한 PLOSL을 유발합니다. 이 유전자에 대해 서로 다른 아이소폼(isoform)을 암호화하는 여러 대체 전사체 변이체(transcript variant)가 확인되었습니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
MyBioSource	R247-210094-01	MBS9443911	TYROBP, Polyclonal Antibody	Rabbit	Polyclonal	Human	Most Applications	0.1 mL
MyBioSource	R247-154554-01	MBS4762183	DAP12 (TYROBP), Monoclonal Antibody	Rabbit	Monoclonal	Human	WB; IHC-P; ICC; IF; FC/FACS	0.1 mL
Cloud-Clone	T813-115222-01	MAG524Hu21	Monoclonal Antibody to TYRO Protein Tyrosine Kinase Binding Protein (TYROBP)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-126893-01	PAG524Hu01	Polyclonal Antibody to TYRO Protein Tyrosine Kinase Binding Protein (TYROBP)	Rabbit	Polyclonal	Human	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-208019-01	MBS9406130	TYROBP, Polyclonal Antibody	Rabbit	Polyclonal	Human	WB; IHC	0.05 mL
MyBioSource	R247-194354-01	MBS8516750	TYROBP, Antibody			Human	WB; IHC	0.1 mg

견적	제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
	Cloud-Clone	T813-148375-01	SEG524Hu	ELISA Kit for TYRO Protein Tyrosine Kinase Binding Protein (TYROBP)	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.053ng/mL.	96T
	MyBioSource	R247-197426-01	MBS8820200	TYROBP (TYRO Protein Tyrosine Kinase Binding Protein), ELISA Kit	Mouse	ELISA		0.16 ng/mL	48-Strip-Wells

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Cloud-Clone	T813-140136-01	RPG524Hu01	Recombinant TYRO Protein Tyrosine Kinase Binding Protein (TYROBP)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-132912-01	MBS2123836	TYRO Protein Tyrosine Kinase Binding Protein (TYROBP), Recombinant Protein	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).	0.01 mg
MyBioSource	R247-174685-01	MBS7058015	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
MyBioSource	R247-173283-01	MBS7043526	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-111834-01	MBS1203589	TYRO protein tyrosine kinase-binding protein (TYROBP)-VLPs, Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
MyBioSource	R247-173285-01	MBS7043528	TYRO protein tyrosine kinase-binding protein (Tyrobp), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-173284-01	MBS7043527	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-174686-01	MBS7058016	TYRO protein tyrosine kinase-binding protein (Tyrobp), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
Abnova	U731-104272-01	H00007305-P01	TYROBP (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
Abnova	U731-104273-01	H00007305-Q01	TYROBP (Human) Recombinant Protein (Q01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
MyBioSource	R247-174684-01	MBS7058014	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-175184-01	MBS7101107	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-112412-01	MBS1235020	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-115218-01	MBS1366034	TYRO protein tyrosine kinase-binding protein (Tyrobp), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-175118-01	MBS7096562	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-112652-01	MBS1249326	TYRO protein tyrosine kinase-binding protein (Tyrobp), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-175109-01	MBS7095910	TYRO protein tyrosine kinase-binding protein (TYROBP), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell

TYROBP — 카탈로그 25건

유전자 개요

관련 표적