TNNI3 — 카탈로그 54건

Gene TNNI3 NCBI Gene 7137

취급 제조사 7곳

Elabscience Biosynth MyBioSource ELK Biotechnology Cusabio Abnova Abbexa

국내 소싱 가능

54건

유전자 개요

TNNI3는 심장 트로포닌 I(cardiac troponin I, TnI) 단백질을 암호화하며, TnI는 트로포닌 T(TnT)·트로포닌 C(TnC)와 함께 줄무늬근(striated muscle) 얇은 필라멘트의 트로포닌 복합체(troponin complex)를 이루는 억제 소단위로서 액틴-미오신 상호작용을 차단해 근육 이완을 매개한다. 심장 TnI는 심장근육 조직에서만 발현되며, TNNI3의 돌연변이는 가족성 비대심근병증 7형(familial hypertrophic cardiomyopathy type 7, CMH7)과 가족성 제한심근병증(restrictive cardiomyopathy, RCM)을 유발한다. 트로포닌 I는 심부전 및 허혈성 심장질환 진단에 활용되며, 트로포닌 수치 상승은 중등도·중증 코로나바이러스감염증-19(COVID-19) 입원 환자의 급성 심근 손상 지표이자 심혈관질환 환자의 높은 사망 위험과 연관된 것으로 보고된다.

Ion homeostasisStriated Muscle Contraction

hypertrophic cardiomyopathycardiomyopathy, familial restrictive, 1dilated cardiomyopathy 1FFdilated cardiomyopathy 2Ahypertrophic cardiomyopathy 7Rare familial disorder with hypertrophic cardiomyopathydilated cardiomyopathycardiomyopathy

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. · Circulation (2003)Evidence-Based Assessment of Genes in Dilated Cardiomyopathy. · Circulation (2021)Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes. · Circ Genom Precis Med (2019)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Elabscience	T619-100735-01	D-AB-10070L	TNNI3/cTn-I Polyclonal Antibody(D-AB-10070L)	Rabbit	Polyclonal	Mouse, Rat	WB	100μL
Biosynth	F502-130582-01	70R-35368	TNNI3 antibody	Rabbit	Polyclonal	TNNI3 antibody detects endogenous levels of total TNNI3 protein; Cross: Mouse, Rat	WB, IHC, IF, ELISA	0.1 mg
Biosynth	F502-105927-01	10R-6091	TNNI3 antibody	Mouse	Monoclonal	Human; Cross: Human	IHC, WB	100 ul
Biosynth	F502-105926-01	10R-6090	TNNI3 antibody	Mouse	Monoclonal	Human; Cross: Human, Dog, Monkey	IF, WB	100 ul
Biosynth	F502-131416-01	70R-36382	TNNI3 antibody	Rabbit	Polyclonal	TNNI3 antibody detects endogenous levels of total TNNI3 protein; Cross: Mouse, Rat	WB, IHC, ELISA	0.1 mg
Biosynth	F502-130860-01	70R-35706	TNNI3 antibody (Thr142)	Rabbit	Polyclonal	Human, Mouse, Rat; Cross: Mouse, Rat - Reactive with proteins phosphorylated as follows: Human: Thr142, Mouse: Thr143, Rat: Thr143	WB, ELISA	0.1 mg
Biosynth	F502-131145-01	70R-36027	TNNI3 antibody (Ser22+Ser23)	Rabbit	Polyclonal	Human, Mouse, Rat; Cross: Mouse, Rat - Reactive with proteins phosphorylated as follows: Human: Ser22+Ser23, Mouse: Ser22+Ser23, Rat: Ser22+Ser23	WB, IHC, ELISA	0.1 mg
Biosynth	F502-105928-01	10R-6092	TNNI3 antibody	Mouse	Monoclonal	Human; Cross: Human	IHC, WB	100 ul
MyBioSource	R247-146285-01	MBS315579	Troponin I-Cardiac (27-39 Region) (TNNI3), Polyclonal Antibody	Goat	Polyclonal	Human, Cat	EIA/ELISA; Immunoassay Antibody Pairs	1 mg
MyBioSource	R247-155929-01	MBS530749	Troponin I (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; IHC; IP; WB	1 mg
MyBioSource	R247-146158-01	MBS312459	Troponin I-Cardiac (148-158 Region) (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Human	EIA/ELISA; Western Blot; Immunohistochemistry; Immunoprecipitation	1 mg
MyBioSource	R247-146102-01	MBS311148	Troponin I-Cardiac (169-184 Region) (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Human	EIA/ELISA; LF; Immunoassay Antibody Pairs; Western Blot	1 mg
MyBioSource	R247-112795-01	MBS125497	Troponin I (TNNI3), Polyclonal Antibody	Rabbit	Polyclonal	Mouse, Rat	WB; IHC; IP	0.02 mL
MyBioSource	R247-146108-01	MBS311216	Troponin I-Cardiac (186-192 Region) (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Cat	EIA/ELISA; Western Blot	1 mg
MyBioSource	R247-146103-01	MBS311166	Troponin I-Cardiac (25-40 Region) (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Cat	EIA/ELISA; Western Blot	1 mg
MyBioSource	R247-159904-01	MBS609006	Troponin I, cardiac muscle, PHOSPHORYLATED (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat, Bovine, Porcine, Goat, Feline, Canine	ELISA; WB	0.2 mg
MyBioSource	R247-155910-01	MBS530671	Troponin I (TNNI3), Monoclonal Antibody	Mouse	Monoclonal	Human	User optimized
ELK Biotechnology	T376-120045-01	ES4400	Troponin I-C rabbit pAb	Rabbit	Polyclonal	Mouse;Rat	WB;IHC;IF;ELISA	50μL
Biosynth	F502-117854-01	70R-15072	TNNI3 antibody (Ser23/24)	Rabbit	Polyclonal		WB	100 ul
Biosynth	F502-109579-01	20R-2873	TNNI3 antibody	Rabbit			WB	100 ul

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cusabio	T094-100829-01	CSB-E08421m	Mouse cardiac troponin Ⅰ(cTn-Ⅰ) ELISA kit	Mus musculus (Mouse)	ELISA	serum, plasma	3.9 pg/mL	96T,5×96T,10×96T
Cusabio	T094-100329-01	CSB-E05139h	Human cardiac troponin Ⅰ,cTn-ⅠELISA Kit	Homo sapiens (Human)	ELISA	serum, plasma, urine	11.75 pg/mL	96T,5×96T,10×96T
Cusabio	T094-101490-01	CSB-E11286Rb	Rabbit cardiac troponin Ⅰ,cTn-ⅠELISA Kit	Oryctolagus cuniculus (Rabbit)	ELISA	serum, plasma, tissue homogenates	11.75 pg/mL	96T,5×96T,10×96T
MyBioSource	R247-135591-01	MBS2502538	TNNI3/cTn-I, ELISA Kit	Mouse	ELISA	Serum, Plasma And Other Biological Fluids	18.75 pg/mL	24 Tests
MyBioSource	R247-173021-01	MBS703536	troponin I type 3 (cardiac)	Mouse	ELISA	Serum, plasma	< 3.9 pg/ml	24-Strip-Wells
MyBioSource	R247-151974-01	MBS450139	Troponin I Type 3, Cardiac (TNNI3), ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	13.6pg/mL	48 Tests
Abnova	U731-112304-01	KA2485	TNNI3 (Rabbit) ELISA Kit	Rabbit	WB, IHC, ELISA	Serum	0.156 to 10 ng/mL	1 Kit
Abnova	U731-112258-01	KA2431	TNNI3 (Dog) ELISA Kit	Dog	WB, IHC, ELISA	Plasma, Serum	0.039 to 2.5 ng/mL	1 Kit
Abnova	U731-112286-01	KA2465	Tnni3 (Mouse) ELISA Kit	Mouse	WB, IHC, ELISA	Plasma, Serum	0.039 to 2.5 ng/mL	1 Kit
Abnova	U731-112297-01	KA2478	TNNI3 (Pig) ELISA Kit	Pig	WB, IHC, ELISA	Plasma	0.039 to 2.5 ng/mL	1 Kit
Abnova	U731-112318-01	KA2500	Tnni3 (Rat) ELISA Kit	Rat	WB, IHC, ELISA	Serum		1 Kit
Abnova	U731-112306-01	KA2487	TNNI3 (Rabbit) ELISA Kit	Rabbit	WB, IHC, ELISA	Plasma, Serum	0.019 to 1.25 ng/mL	1 Kit
Abnova	U731-112299-01	KA2480	TNNI3 (Pig) ELISA Kit	Pig	WB, IHC, ELISA	Plasma, Serum	0.0156 to 1.0 ng/mL	1 Kit
Abnova	U731-112247-01	KA2420	TNNI3 ELISA Kit	Bovine	WB, IHC, ELISA	Serum		1 Kit
Abnova	U731-112319-01	KA2501	Tnni3 (Rat) ELISA Kit	Rat	WB, IHC, ELISA	Plasma, Serum	0.039 to 2.5 ng/mL	1 Kit
Abnova	U731-112317-01	KA2499	Tnni3 (Rat) ELISA Kit	Rat	WB, IHC, ELISA	Plasma (EDTA)	0.156 to 10 ng/mL	1 Kit
Abnova	U731-112273-01	KA2446	TNNI3 (Monkey) ELISA Kit	Monkey	WB, IHC, ELISA	Plasma, Serum	0.039 to 2.5 ng/mL	1 Kit
Abnova	U731-112298-01	KA2479	TNNI3 (Pig) ELISA Kit	Pig	WB, IHC, ELISA	Serum	1.56 to 10 ng/mL	1 Kit
Abnova	U731-112257-01	KA2430	TNNI3 (Dog) ELISA Kit	Dog	WB, IHC, ELISA	Serum	0.156 to 10 ng/mL	1 Kit
Abnova	U731-112272-01	KA2445	TNNI3 (Monkey) ELISA Kit	Monkey	WB, IHC, ELISA	Serum	0.156 to 10 ng/mL	1 Kit
Abnova	U731-112264-01	KA2437	Tnni3 (Guinea Pig) ELISA Kit	Guinea pig	WB, IHC, ELISA	Serum	0.2 to 12.5 ng/mL	1 Kit
MyBioSource	R247-126887-01	MBS2021490	Troponin I Type 3, Cardiac (TNNI3), ELISA Kit	Human	ELISA	Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and other biological fluids	11.3pg/mL	24-Strip-Wells
MyBioSource	R247-182370-01	MBS7248904	Troponin I, cardiac muscle (TNNI3), ELISA Kit	Monkey	ELISA	Serum, plasma, cell culture supernatants, body fluid and tissue homogenate	1.0 pg/mL	48-Strip-Wells
MyBioSource	R247-180471-01	MBS7217823	Troponin I, cardiac muscle	Rabbit	ELISA	Serum, Plasma, Cell Culture Supernatants, Body Fluid And Tissue Homogenate	1.0 pg/mL.	48-Strip-Wells
MyBioSource	R247-181615-01	MBS7236840	Troponin I, cardiac muscle (TNNI3), ELISA Kit	Mouse	ELISA	Serum, plasma, cell culture supernatants, body fluid and tissue homogenate	1.0 pg/mL	48-Strip-Wells
MyBioSource	R247-188364-01	MBS764367	cardiac Troponin I (cTn-I/TNNI3), ELISA Kit	Monkey	ELISA	Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples	18.75pg/ml	48-Strip-Wells
Abbexa	F158-120421-01	abx481039	Human TGM2/FABP3/FGF23/GDF15/LGALS3/IL1RL1/TNNI3 Multiplex Assay Kit	Human	FCM	Serum, plasma, tissue homogenates, cell lysates and other biological fluids.		96 tests
Abnova	U731-114170-01	KA7041	FastELISA™ TNNI3 (Human) ELISA Kit			Serum, Plasma, etc.	19.6 pg/mL	1 Kit
MyBioSource	R247-171910-01	MBS700416	troponin I type 3 (cardiac)	Human	ELISA	Serum, plasma, urine	11.75 pg/ml	24-Strip-Wells

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Elabscience	T619-102623-01	E-CL-R0721	Rat cTn-I/TNNI3 (Cardiac Troponin I) CLIA Kit	Rat	CLIA	Serum, plasma and other biological fluids	7.5 pg/mL	96T, 48T, 24T, 96T5, 96T10
Elabscience	T619-102430-01	E-CL-H0495	Human cTn-I/TNNI3 (cardiac Troponin I)CLIA Kit	Human	CLIA	Serum, plasma and other biological fluids	46.88 pg/mL	96T, 48T, 24T, 96T5, 96T10
MyBioSource	R247-137460-01	MBS2532957	cTn-I/TNNI3 (cardiac Troponin I), CLIA Kit	Human	CLIA		Min: 46.875pg/mL; Max: 5000pg/mL	96 Tests

견적	제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
	MyBioSource	R247-115925-01	MBS140908	Cardiac Troponin-I (TNNI3), Recombinant Protein	E Coli			0.1 mg
	Abnova	U731-104175-01	H00007137-P01	TNNI3 (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re

TNNI3 — 카탈로그 54건

유전자 개요

관련 표적