TLR4 — 카탈로그 89건

Gene TLR4 NCBI Gene 7099

취급 제조사 6곳

Cloud-Clone Biosynth MyBioSource Cusabio Elabscience Abnova

국내 소싱 가능

89건

유전자 개요

TLR4가 암호화하는 단백질은 병원체 인식과 선천면역(innate immunity) 활성화에 핵심적 역할을 하는 Toll 유사 수용체(Toll-like receptor, TLR) 계열의 구성원으로, 초파리(Drosophila)부터 인간까지 고도로 보존되어 있으며 감염체에 발현되는 병원체 관련 분자 패턴(pathogen-associated molecular patterns)을 인식해 효과적 면역에 필요한 사이토카인(cytokine) 생성을 매개한다. 표면 TLR4는 in silico 연구에서 코로나바이러스감염증-2019(COVID-19)의 원인체인 SARS-CoV-2의 스파이크 단백질과 특히 강하게 결합하는 것으로 나타났으며, 대부분의 그람음성균에 존재하는 지질다당류(lipopolysaccharide, LPS)가 유도하는 신호전달에도 관여한다. 이 유전자의 변이는 LPS 반응성 차이 및 연령관련 황반변성(age-related macular degeneration) 감수성과 연관되며, 서로 다른 아이소폼(isoform)을 암호화하는 여러 전사체 변이체가 확인되었다.

Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)Caspase activation via Death Receptors in the presence of ligandER-Phagosome pathwayHeme signalingIKK complex recruitment mediated by RIP1IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulationIRAK4 deficiency (TLR2/4)MyD88 deficiency (TLR2/4)MyD88-independent TLR4 cascade MyD88:MAL(TIRAP) cascade initiated on plasma membrane

basophil measurementmajor depressive disorderprostate specific antigen amounttoll-like receptor 4:Lymphocyte antigen 96 complex amounttype 2 diabetes mellitustonsillectomy risk measurementbody mass indexSepsis

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) LPS/TLR4 signal transduction pathway. · Cytokine (2008)TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling. · Cell Mol Life Sci (2021)TAK-242 (resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. · Mol Pharmacol (2011)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cloud-Clone	T813-108621-01	LAA753Mu81	FITC-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Antibody labeling	Murine	WB; IHC; ICC; IF.	100µl
Cloud-Clone	T813-108623-01	LAA753Ra81	FITC-Linked Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Antibody labeling	Rat	WB; IHC; ICC; IF.	100µl
Biosynth	F502-117350-01	70R-14023	TLR4 antibody	Rabbit	Polyclonal	Human	WB, IHC-P	0.1 mg
Biosynth	F502-124104-01	70R-20849	TLR4 antibody	Rabbit	Polyclonal	Human; Cross: Human, Mouse, Rat, Bovin	ELISA, WB	50 ul
Cloud-Clone	T813-112408-01	MAA753Ra21	Monoclonal Antibody to Toll Like Receptor 4 (TLR4)	Mouse	Monoclonal	Rat	ICC/IF	100µl
Cloud-Clone	T813-119488-01	PAA753Mu01	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Murine	WB	100µl
Cloud-Clone	T813-112405-01	MAA753Bo21	Monoclonal Antibody to Toll Like Receptor 4 (TLR4)	Mouse	Monoclonal	Bovine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-119489-01	PAA753Mu02	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Murine	WB	100µl
Cloud-Clone	T813-119484-01	PAA753Bo01	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Bovine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-119490-01	PAA753Ra01	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Rat	WB; IHC	100µl
Cloud-Clone	T813-112406-01	MAA753Hu21	Monoclonal Antibody to Toll Like Receptor 4 (TLR4)	Mouse	Monoclonal	Human	WB	100µl
Cloud-Clone	T813-119486-01	PAA753Hu02	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Human	IHC	100µl
Cloud-Clone	T813-128929-01	PSA753Hu01	Antibody Pair for Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Human	ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.	96T*10
Cloud-Clone	T813-119485-01	PAA753Hu01	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Human	WB; FCM	100µl
Cloud-Clone	T813-112407-01	MAA753Hu22	Monoclonal Antibody to Toll Like Receptor 4 (TLR4)	Mouse	Monoclonal	Human	WB	100µl
Cloud-Clone	T813-119487-01	PAA753Hu08	Polyclonal Antibody to Toll Like Receptor 4 (TLR4)	Rabbit	Polyclonal	Human	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-133951-01	MBS2152073	Toll Like Receptor 4 (TLR4), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat	WB; IHC; ICC; IP	0.1 mL
MyBioSource	R247-112792-01	MBS125491	Toll-like Receptor 4 (TLR4), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	WB; IF	0.02 mL
MyBioSource	R247-147395-01	MBS3214163	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Pig	IHC; WB	0.1 mL
MyBioSource	R247-170680-01	MBS668019	TLR4, Monoclonal Antibody	Mouse	Monoclonal	Human, Mouse, Rat	WB; IHC	0.025 mg
MyBioSource	R247-124858-01	MBS2002584	Toll Like Receptor 4 (TLR4), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB	0.1 mL
MyBioSource	R247-188957-01	MBS805758	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	FC/FACS; IHC; ICC; WB	0.1 mg
MyBioSource	R247-125215-01	MBS2004887	Toll Like Receptor 4 (TLR4), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.	0.1 mL
MyBioSource	R247-188951-01	MBS805668	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	FC/FACS; IHC; ICC; WB	0.1 mg
MyBioSource	R247-188946-01	MBS805478	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	FC/FACS; IHC; ICC; WB	0.1 mg
MyBioSource	R247-151207-01	MBS4381554	CD284 (TLR4), Monoclonal Antibody	Rabbit	Monoclonal	Human, Rat, Dog, Guinea Pig, Monkey, Pig	ELISA	0.02 mg
MyBioSource	R247-170774-01	MBS668706	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Mouse	WB	0.025 mg
MyBioSource	R247-132486-01	MBS2111174	Toll Like Receptor 4 (TLR4), Monoclonal Antibody	Mouse	Monoclonal	Human, Mouse, Rat	WB; IHC; ICC; IP	0.1 mL
MyBioSource	R247-188960-01	MBS805862	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	FC/FACS; IHC; ICC; WB	0.1 mg
MyBioSource	R247-159482-01	MBS601832	TLR4/MD-2 Complex, TLR4, Monoclonal Antibody	Rat	Monoclonal	Mouse	WB; IP; FC/FACS	0.1 mg
MyBioSource	R247-188943-01	MBS805401	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	FC/FACS; IHC; ICC; WB	0.1 mg
MyBioSource	R247-199442-01	MBS9131390	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Mouse, Rat	WB	0.02 mL
MyBioSource	R247-151438-01	MBS438978	CD284 (TLR4), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat, Dog, Guinea Pig, Monkey, Pig	Functional Studies; FC/FACS; IF; Immunohistochemistry (IHC) Formalin	0.02 mg
MyBioSource	R247-131046-01	MBS2090574	Toll Like Receptor 4 (TLR4), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat	WB; IHC; ICC; IP	0.1 mL
MyBioSource	R247-192852-01	MBS834441	Toll-like receptor 4 (TLR4), Monoclonal Antibody	Rat	Monoclonal	Mouse	User optimized	0.05 mg
MyBioSource	R247-137000-01	MBS2523528	TLR4, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA; IHC	0.02 mL
MyBioSource	R247-126103-01	MBS2012886	Toll Like Receptor 4 (TLR4), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; ICC; IF.	0.1 mL
MyBioSource	R247-192632-01	MBS832508	Toll-like receptor 4 (TLR4), Monoclonal Antibody	Mouse	Monoclonal	Human	FC/FACS
Biosynth	F502-140455-01	70R-9659	TLR4 antibody	Rabbit	Polyclonal	Human; Cross: Predicted: Human, Pig	WB	100 ul
Biosynth	F502-140483-01	70R-9688	TLR4 antibody	Rabbit	Polyclonal	Human	WB	100 ul
MyBioSource	R247-125282-01	MBS2005383	Toll Like Receptor 4 (TLR4), Antibody	Rabbit		Human, Mouse, Rat	WB; IHC; ICC; IP	0.1 mL

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cloud-Clone	T813-106350-01	KSA753Hu01	ELISA Kit DIY Materials for Toll Like Receptor 4 (TLR4)	Human	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids.	0.118ng/mL	96T*10
Cloud-Clone	T813-106351-01	KSA753Mu01	ELISA Kit DIY Materials for Toll Like Receptor 4 (TLR4)	Murine	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.054ng/mL	96T*10
Cloud-Clone	T813-106352-01	KSA753Ra01	ELISA Kit DIY Materials for Toll Like Receptor 4 (TLR4)	Rat	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.071ng/mL	96T*10
Cusabio	T094-102332-01	CSB-E15822r	Rat toll-like receptor 4 (TLR4) ELISA Kit	Rattus norvegicus (Rat)	ELISA	serum, plasma, cell culture supernates, tissue homogenates	0.156 ng/mL	96T,5×96T,10×96T
Cusabio	T094-102191-01	CSB-E14275m	Mouse Soluble Toll-like Receptor 4,sTLR4 ELISA Kit	Mus musculus (Mouse)	ELISA	serum, plasma, tissue homogenates	0.039 ng/mL	96T,5×96T,10×96T
Cusabio	T094-101741-01	CSB-E12954h	Human toll-like receptor 4,TLR4 ELISA Kit	Homo sapiens (Human)	ELISA	serum, plasma, tissue homogenates	0.039 ng/mL	96T,5×96T,10×96T
MyBioSource	R247-172573-01	MBS701743	toll-like receptor 4 (TLR4), ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates	The minimum detectable dose of human TLR4 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.	24-Strip-Wells
Elabscience	T619-103030-01	E-EL-M2417	Mouse TLR4(Toll-Like Receptor 4) ELISA Kit	Mouse	ELISA	Serum, plasma and other biological fluids	0.1 ng/mL	96T
MyBioSource	R247-102060-01	MBS026966	Toll Like Receptor4 (TLR4), ELISA Kit	Mouse	ELISA		0.1ng/ml	48-Strip-Wells
MyBioSource	R247-185360-01	MBS737862	Toll Like Receptor4 (TLR4), ELISA Kit	Sheep	ELISA	Serum, plasma, cell culture supernatants, body fluid and tissue homogenate	0.1 ng/mL	48-Strip-Wells
MyBioSource	R247-142192-01	MBS2702401	Toll Like Receptor 4 (TLR4), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids	< 0.118ng/mL	24-Strip-Wells
MyBioSource	R247-127037-01	MBS2022178	Toll Like Receptor 4 (TLR4), ELISA Kit	Mouse	ELISA	Mouse tissue homogenates, cell lysates, cell culture supernates and other biological fluids	< 0.054ng/mL	24-Strip-Wells
MyBioSource	R247-142193-01	MBS2702403	Toll Like Receptor 4 (TLR4), ELISA Kit	Rat	ELISA	Rat tissue homogenates, cell lysates, cell culture supernates and other biological fluids	< 0.071ng/mL	24-Strip-Wells
Cloud-Clone	T813-144545-01	SEA753Ra	ELISA Kit for Toll Like Receptor 4 (TLR4)	Rat	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.071ng/mL.	96T
Cloud-Clone	T813-144541-01	SEA753Bo	ELISA Kit for Toll Like Receptor 4 (TLR4)	Bovine	ELISA	Serum, plasma, tissue homogenates, cell lysates and other biological fluids	0.281ng/mL.	96T
Cloud-Clone	T813-144543-01	SEA753Mu	ELISA Kit for Toll Like Receptor 4 (TLR4)	Murine	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.054ng/mL.	96T
Cloud-Clone	T813-144542-01	SEA753Hu	ELISA Kit for Toll Like Receptor 4 (TLR4)	Human	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.118ng/mL.	96T
Cloud-Clone	T813-144544-01	SEA753Po	ELISA Kit for Toll Like Receptor 4 (TLR4)	Porcine	ELISA	serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.055ng/mL.	96T

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
MyBioSource	R247-129063-01	MBS2034524	Toll Like Receptor 4 (TLR4), Recombinant Protein	E Coli Source: Prokaryotic expression	Human	SDS-PAGE; WB; ELISA; IP	0.01 mg
Cloud-Clone	T813-131984-01	RPA753Cp01	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Caprine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131985-01	RPA753Hu01	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131986-01	RPA753Hu02	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131988-01	RPA753Mu02	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131983-01	RPA753Bo01	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Bovine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131989-01	RPA753Ra01	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Rat	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-131987-01	RPA753Mu01	Recombinant Toll Like Receptor 4 (TLR4)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-125681-01	MBS2009867	Toll Like Receptor 4 (TLR4), Recombinant Protein	E Coli		SDS-PAGE; WB; ELISA; IP	0.01 mg
MyBioSource	R247-125717-01	MBS2010140	Toll Like Receptor 4 (TLR4), Recombinant Protein	E Coli		SDS-PAGE; WB; ELISA; IP	0.01 mg
MyBioSource	R247-114182-01	MBS1300569	Toll-like receptor 4 (Tlr4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
MyBioSource	R247-109498-01	MBS1069936	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.5 mg
MyBioSource	R247-211889-01	MBS956975	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			1 mg
MyBioSource	R247-174508-01	MBS7053539	Toll-like receptor 4 (Tlr4), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-115000-01	MBS1355880	Toll-like receptor 4 (Tlr4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.02 mg
MyBioSource	R247-125643-01	MBS2009564	Toll Like Receptor 4 (TLR4), Recombinant Protein	E Coli		Positive Control; Immunogen; SDS-PAGE; WB	0.01 mg
Abnova	U731-104139-01	H00007099-Q01	TLR4 (Human) Recombinant Protein (Q01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
Abnova	U731-104137-01	H00007099-G01	TLR4 (Human) Recombinant Protein	Wheat Germ (in vitro)	Human	AP,Func,Screening
Abnova	U731-104138-01	H00007099-P01	TLR4 (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
MyBioSource	R247-114266-01	MBS1306832	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-116506-01	MBS1427811	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-113971-01	MBS1292893	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-117796-01	MBS1476517	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-115242-01	MBS1368074	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-117827-01	MBS1478795	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-117917-01	MBS1484700	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-114500-01	MBS1324699	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-174658-01	MBS7057302	Toll-like receptor 4 (TLR4), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell

견적	제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
	Cloud-Clone	T813-142406-01	SCA753Mu	CLIA Kit for Toll Like Receptor 4 (TLR4)	Murine	CLIA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids	5.5pg/mL.	96T
	MyBioSource	R247-137329-01	MBS2530869	TLR4 (Toll-Like Receptor 4), CLIA Kit	Human	CLIA		Min: 37.5pg/mL; Max: 4000pg/mL	96 Tests

TLR4 — 카탈로그 89건

유전자 개요

관련 표적