TIMELESS — 카탈로그 22건
Gene TIMELESS
NCBI Gene 8914
취급 제조사 4곳
국내 소싱 가능
22건
유전자 개요
이 유전자가 지정하는 단백질은 손상이나 스트레스 후 세포 생존, DNA 중합효소 엡실론(DNA polymerase epsilon) 활성 증가, 텔로미어 길이 유지, 상피세포 형태형성(epithelial cell morphogenesis)에 관여하는 매우 보존된 단백질입니다. 또한 이 단백질은 생체 시계(circadian rhythm) 자율 조절 고리에서 역할을 수행하며, PERIOD 유전자(PER1, PER2, PER3) 등과 상호작용하여 CLOCK/ARNTL에 의한 PER1 활성화를 하향 조절합니다. 이 유전자 또는 그 발현의 변화는 전립선암, 폐암, 유방암 및 정신 질환의 발병을 촉진할 수 있습니다.
Processing of DNA double-strand break ends
Familial advanced sleep-phase syndromelevel of endophilin-A3 in blood serumocular hypertensiontrait in response to triamcinolone acetonideneurodegenerative diseaseglutamine measurementresponse to vaccinecytokine measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Nuclear cGAS suppresses DNA repair and promotes tumorigenesis. · Nature (2018)Transcription-replication conflicts underlie sensitivity to PARP inhibitors. · Nature (2024)Structure of a human replisome shows the organisation and interactions of a DNA replication machine. · EMBO J (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109214-01 | CSB-PA892360LA01HU | TIMELESS Antibody | Rabbit | Polyclonal | Human | ELISA, IHC | 50μg, 100μg | |
| Abbexa | F158-105013-01 | abx116104 | Protein Timeless Homolog (TIMELESS) Antibody | Rabbit | Polyclonal | Human | ELISA, WB, IHC | 100 µl | |
| Abbexa | F158-106692-01 | abx145024 | Protein Timeless Homolog (TIMELESS) Antibody | Rabbit | Polyclonal | Human | ELISA, WB | 100 µg | |
| Abbexa | F158-111207-01 | abx238694 | Protein Timeless Homolog (TIMELESS) Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC | 100 µg | |
| Abbexa | F158-111277-01 | abx240110 | Protein Timeless Homolog (TIMELESS) Antibody | Rabbit | Polyclonal | Human | ELISA, WB | 100 µg | |
| Abbexa | F158-100220-01 | abx003158 | Protein Timeless Homolog (TIMELESS) Antibody | Rabbit | Polyclonal | Human, Mouse | WB | 60 µl | |
| MyBioSource | R247-149431-01 | MBS3901461 | Timeless, Polyclonal Antibody | Rabbit | Polyclonal | Human | IP | 0.01 mg | |
| MyBioSource | R247-149432-01 | MBS3901462 | Timeless, Polyclonal Antibody | Rabbit | Polyclonal | Human | WB; IP; IHC | 0.002 mg | |
| Biosynth | F502-124078-01 | 70R-20825 | TIMELESS antibody | Rabbit | Polyclonal | Human; Cross: Human | ELISA, IHC, WB | 50 ul | |
| MyBioSource | R247-176484-01 | MBS711823 | timeless homolog, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB; IHC | 0.1 mL | |
| MyBioSource | R247-146726-01 | MBS3204063 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Sheep, Zebrafish, Horse | WB | 0.1 mL | |
| MyBioSource | R247-146727-01 | MBS3204064 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Dog, Guinea Pig, Pig, Sheep, Horse | WB | 0.1 mL | |
| MyBioSource | R247-192638-01 | MBS832534 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Sheep, Zebrafish, Horse | WB | 0.1 mL | |
| MyBioSource | R247-192963-01 | MBS835743 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Dog | WB | 0.1 mL | |
| MyBioSource | R247-123256-01 | MBS1756632 | Timeless, Monoclonal Antibody | Rabbit | Monoclonal | Human | WB; IHC; ICC; IF | 0.03 mL | |
| MyBioSource | R247-192416-01 | MBS8308404 | Timeless, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB | 0.03 mL | |
| MyBioSource | R247-146594-01 | MBS3201914 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Sheep, Horse | IHC; WB | 0.1 mL | |
| MyBioSource | R247-123057-01 | MBS1754828 | TIMELESS, Polyclonal Antibody | Rabbit | Polyclonal | Human | WB; ELISA | 0.01 mg | |
| Biosynth | F502-108496-01 | 20R-1198 | TIMELESS antibody | Rabbit | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish | WB | 100 ul | ||
| Biosynth | F502-108497-01 | 20R-1199 | TIMELESS antibody | Rabbit | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Yeast | WB | 100 ul | ||
| Biosynth | F502-138888-01 | 70R-8020 | TIMELESS antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep | IHC, WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
ATM
Processing of DNA double-strand break ends
BRCA1
Processing of DNA double-strand break ends
RPA1
Processing of DNA double-strand break ends
CDK2
Processing of DNA double-strand break ends
BARD1
Processing of DNA double-strand break ends
ATR
Processing of DNA double-strand break ends
BRIP1
Processing of DNA double-strand break ends
NBN
Processing of DNA double-strand break ends