해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

TBK1 — 카탈로그 65건

Gene TBK1 NCBI Gene 29110

취급 제조사 6곳

Cusabio Abbexa MyBioSource Cloud-Clone Biosynth Abnova

국내 소싱 가능

65건

유전자 개요

TBK1이 암호화하는 단백질은 IKB 키나아제(IKB kinase)와 유사하여, 특정 성장인자에 반응해 NF-κB(NFKB) 복합체의 활성화를 매개할 수 있다. 평소 NFKB는 IKB 단백질이 세포질(cytoplasm)에 가두어 비활성 상태로 유지되지만, IKB 키나아제가 IKB의 세린 잔기를 인산화(phosphorylation)하면 이 단백질들은 유비퀴틴화(ubiquitination) 경로를 통한 분해 표지가 되고, 그 결과 NFKB의 활성화와 핵 이동이 가능해진다. TBK1은 또한 항바이러스 선천면역 반응에서 중요한 키나아제이다.

Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)DDX58/IFIH1-mediated induction of interferon-alpha/betaIRF3 mediated activation of type 1 IFNIRF3-mediated induction of type I IFNInterleukin-37 signalingNegative regulators of DDX58/IFIH1 signalingPINK1-PRKN Mediated MitophagyPotential therapeutics for SARSRegulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation

frontotemporal dementia and/or amyotrophic lateral sclerosis 4Herpetic encephalitisamyotrophic lateral sclerosisAmyotrophic lateral sclerosisCOVID-19autoinflammation with arthritis and vasculitishemoglobin measurementaxial length measurement

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. · Nature (2009)IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. · Nat Immunol (2003)The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. · Immunity (2008)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-110223-01	CSB-RA932866A0HU	TBK1 Recombinant Monoclonal Antibody	Rabbit	Monoclonal	Human	ELISA, IHC, FC	50μl, 100μl
Cusabio	T094-107181-01	CSB-PA023232LA01HU	TBK1 Antibody	Rabbit	Polyclonal	Human, Mouse	ELISA, WB, IHC, IF	50μg, 100μg
Abbexa	F158-116885-01	abx349520	Serine/threonine-protein kinase TBK1 (TBK1) Antibody (Biotin)	Rabbit	Polyclonal	Human	ELISA	50 µl
Abbexa	F158-116884-01	abx349519	Serine/threonine-protein kinase TBK1 (TBK1) Antibody (FITC)	Rabbit	Polyclonal	Human	FCM, IF	50 µl
Abbexa	F158-116882-01	abx349516	Serine/threonine-protein kinase TBK1 (TBK1) Antibody	Rabbit	Polyclonal	Human	ELISA, WB, IF/ICC	20 µl
Abbexa	F158-116883-01	abx349518	Serine/threonine-protein kinase TBK1 (TBK1) Antibody (HRP)	Rabbit	Polyclonal	Human	ELISA	50 µl
MyBioSource	R247-214996-01	MBS9614191	TBK1, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, Chicken, Zebrafish, Horse	WB; IHC; EIA	0.05 mL
MyBioSource	R247-213700-01	MBS9607679	TBK1, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; IF; ICC; ELISA	0.1 mL
Cloud-Clone	T813-115318-01	MAH061Hu21	Monoclonal Antibody to TANK Binding Kinase 1 (TBK1)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-127116-01	PAH061Hu01	Polyclonal Antibody to TANK Binding Kinase 1 (TBK1)	Rabbit	Polyclonal	Human	WB; IHC	100µl
MyBioSource	R247-118175-01	MBS1489364	Serine/threonine-protein kinase TBK1, Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA	0.05 mg
MyBioSource	R247-113220-01	MBS126808	TBK1, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse	WB; IHC	0.02 mL
MyBioSource	R247-118359-01	MBS1490532	Serine/threonine-protein kinase TBK1, Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA	0.05 mg
Biosynth	F502-137051-01	70R-5838	TBK1 antibody	Rabbit	Polyclonal	TBK1 antibody was raised against the middle region of TBK1; Cross: Human,Mouse,Rat	WB	100 ul
Biosynth	F502-136946-01	70R-5732	TBK1 antibody	Rabbit	Polyclonal	TBK1 antibody was raised against the N terminal of TBK1; Cross: Human,Mouse,Rat	WB	100 ul

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
MyBioSource	R247-152180-01	MBS4502751	TANK Binding Kinase 1 (TBK1), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates or Other Biological Fluids.	0.112ng/mL	48 Tests
MyBioSource	R247-153422-01	MBS454044	TANK Binding Kinase 1 (TBK1), ELISA Kit	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.112ng/mL	48 Tests
MyBioSource	R247-204147-01	MBS9330803	TANK-binding kinase 1 (TBK1), ELISA Kit	Human	ELISA		0.1ng/ml	48-Strip-Wells
MyBioSource	R247-144897-01	MBS2887613	Serine/threonine-protein kinase TBK1, ELISA Kit	Human	ELISA		0.078 ng/mL	48-Strip-Wells
MyBioSource	R247-126697-01	MBS2020540	TANK Binding Kinase 1 (TBK1), ELISA Kit	Human	ELISA	Tissue homogenates, Cell lysates, Cell culture supernates and other biological fluids	0.114ng/mL	24-Strip-Wells
MyBioSource	R247-142614-01	MBS2706304	TANK Binding Kinase 1 (TBK1), ELISA Kit	Human	ELISA	Human tissue homogenates, cell lysates, cell culture supernates and other biological fluids	< 0.114ng/mL	24-Strip-Wells
MyBioSource	R247-197021-01	MBS8803375	TBK1 (TANK Binding Kinase 1), ELISA Kit	Human	ELISA		0.124 ng/mL	48-Strip-Wells
Cloud-Clone	T813-148524-01	SEH061Hu	ELISA Kit for TANK Binding Kinase 1 (TBK1)	Human	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.114ng/mL.	96T
MyBioSource	R247-209237-01	MBS9427001	Serine/threonine-protein kinase TBK1, ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates and other biological fluids.		96 Tests
MyBioSource	R247-204340-01	MBS9334673	TANK-binding kinase 1 (TBK1), ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-217150-01	MBS9917860	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Hamster	ELISA			48-Strip-Wells
MyBioSource	R247-217142-01	MBS9917848	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Bovine	ELISA			48-Strip-Wells
MyBioSource	R247-109857-01	MBS108527	TANK Binding Kinase 1 (TBK1), ELISA Kit	Canine	ELISA			48-Strip-Wells
MyBioSource	R247-105453-01	MBS068033	TANK Binding Kinase 1 (TBK1), ELISA Kit	Hamster	ELISA			48-Strip-Wells
MyBioSource	R247-106876-01	MBS087432	TANK Binding Kinase 1 (TBK1), ELISA Kit	Monkey	ELISA			48-Strip-Wells
MyBioSource	R247-217155-01	MBS9917866	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-217156-01	MBS9917867	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Sheep	ELISA			48-Strip-Wells
MyBioSource	R247-105640-01	MBS070696	TANK Binding Kinase 1 (TBK1), ELISA Kit	Camel	ELISA			48-Strip-Wells
MyBioSource	R247-107370-01	MBS094009	TANK Binding Kinase 1 (TBK1), ELISA Kit	Bovine	ELISA			48-Strip-Wells
MyBioSource	R247-217151-01	MBS9917862	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-217149-01	MBS9917859	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Horse	ELISA			48-Strip-Wells
MyBioSource	R247-104617-01	MBS057406	TANK Binding Kinase 1 (TBK1), ELISA Kit	Horse	ELISA			48-Strip-Wells
MyBioSource	R247-105759-01	MBS072240	TANK Binding Kinase 1 (TBK1), ELISA Kit	Porcine	ELISA			48-Strip-Wells
MyBioSource	R247-107111-01	MBS090575	TANK Binding Kinase 1 (TBK1), ELISA Kit	Human	ELISA			48-Strip-Wells
MyBioSource	R247-106399-01	MBS081195	TANK Binding Kinase 1 (TBK1), ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-106646-01	MBS084412	TANK Binding Kinase 1 (TBK1), ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-217153-01	MBS9917864	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Porcine	ELISA			48-Strip-Wells
MyBioSource	R247-108740-01	MBS103712	TANK Binding Kinase 1 (TBK1), ELISA Kit	Sheep	ELISA			48-Strip-Wells
MyBioSource	R247-105084-01	MBS063434	TANK Binding Kinase 1 (TBK1), ELISA Kit	Cat	ELISA
MyBioSource	R247-217146-01	MBS9917855	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Duck	ELISA
MyBioSource	R247-217145-01	MBS9917853	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Cavy	ELISA
MyBioSource	R247-206601-01	MBS9371349	TANK Binding Kinase 1 (TBK1), ELISA Kit	Plant	ELISA
MyBioSource	R247-217148-01	MBS9917858	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Goat	ELISA
MyBioSource	R247-104823-01	MBS060081	TANK Binding Kinase 1 (TBK1), ELISA Kit	Goose	ELISA
MyBioSource	R247-104272-01	MBS053113	TANK Binding Kinase 1 (TBK1), ELISA Kit	Donkey	ELISA
MyBioSource	R247-105333-01	MBS066717	TANK Binding Kinase 1 (TBK1), ELISA Kit	Chicken	ELISA
MyBioSource	R247-217147-01	MBS9917856	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Fish	ELISA
MyBioSource	R247-217143-01	MBS9917850	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Chicken	ELISA
MyBioSource	R247-217144-01	MBS9917852	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Cat	ELISA
MyBioSource	R247-107268-01	MBS092664	TANK Binding Kinase 1 (TBK1), ELISA Kit	Goat	ELISA
MyBioSource	R247-217154-01	MBS9917865	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Rabbit	ELISA
MyBioSource	R247-217152-01	MBS9917863	Serine/Threonine-Protein Kinase TBK1 (TBK1), ELISA Kit	Pigeon	ELISA
MyBioSource	R247-105745-01	MBS071997	TANK Binding Kinase 1 (TBK1), ELISA Kit	Rabbit	ELISA
MyBioSource	R247-106882-01	MBS087505	TANK Binding Kinase 1 (TBK1), ELISA Kit	Pigeon	ELISA
MyBioSource	R247-109358-01	MBS106352	TANK Binding Kinase 1 (TBK1), ELISA Kit	Duck	ELISA
MyBioSource	R247-104959-01	MBS061949	TANK Binding Kinase 1 (TBK1), ELISA Kit	Fish	ELISA
MyBioSource	R247-107337-01	MBS093566	TANK Binding Kinase 1 (TBK1), ELISA Kit	Cavy	ELISA

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Cloud-Clone	T813-140364-01	RPH061Hu01	Recombinant TANK Binding Kinase 1 (TBK1)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-145457-01	MBS2902396	TBK1 / Serine/Threonine-Protein Kinase TBK1, Recombinant Protein	E Coli		ELISA; WB; AP; Protein Array
Abnova	U731-107874-01	H00029110-P01	TBK1 (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re

TBK1 — 카탈로그 65건

유전자 개요

관련 표적