SUMO2 — 카탈로그 13건
Gene SUMO2
NCBI Gene 6613
취급 제조사 4곳
국내 소싱 가능
13건
유전자 개요
SUMO2(SUMO2)는 SUMO(작은 유비퀴틴(ubiquitin) 유사 수식자) 단백질 군에 속하는 단백질을 암호화한다. 유비퀴틴(ubiquitin)과 유사하게 표적 단백질에 결합해 번역 후 변형(post-translational modification)에 참여하지만, 단백질 분해(degradation)를 겨냥하는 유비퀴틴과 달리 핵 수송(nuclear transport), 전사 조절(transcriptional regulation), 세포자멸사(apoptosis), 단백질 안정성(protein stability) 등의 세포 과정에 관여한다. 카르복시 말단(carboxy-terminus)의 마지막 두 아미노산(amino acid)이 제거되어야 활성화되며, 다수의 위유전자(pseudogene)와 서로 다른 아이소폼(isoform)을 암호화하는 스플라이스 변이체(splice variant)도 특성화되었다.
Formation of Incision Complex in GG-NERProcessing of DNA double-strand break endsRegulation of endogenous retroelements by KRAB-ZFP proteinsSUMO is conjugated to E1 (UBA2:SAE1)SUMO is proteolytically processedSUMO is transferred from E1 to E2 (UBE2I, UBC9)SUMOylation of DNA damage response and repair proteinsSUMOylation of DNA replication proteinsSUMOylation of RNA binding proteinsSUMOylation of SUMOylation proteins
neurodegenerative diseasewhite matter integritymean fractional anisotropy measurementserum gamma-glutamyl transferase measurementhepatocellular carcinomaneuroendocrine neoplasmMyoclonuspoisoning
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) SUMO--nonclassical ubiquitin. · Annu Rev Cell Dev Biol (2000)The post-translational modification, SUMOylation, and cancer (Review). · Int J Oncol (2018)TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation. · Nat Commun (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-119425-01 | MBS150316 | SUMO2/3, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; WB; IHC; IF | 0.1 mg | |
| Biosynth | F502-134847-01 | 70R-50404 | SUMO2/3 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of SUMO2/3 protein; Cross: Mouse, Rat, Bovine, Pig | WB | 100 ul | |
| Biosynth | F502-126273-01 | 70R-30839 | SUMO2/3 antibody | Rabbit | Polyclonal | SUMO2/3 antibody detects endogenous levels of fragment of activated SUMO2/3 resulting from cleavage adjacent to Gly93; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-126253-01 | 70R-30820 | SUMO2/3 antibody | Rabbit | Polyclonal | SUMO2/3 antibody detects endogenous levels of fragment of activated SUMO2/3 resulting from cleavage adjacent to Gly93; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-123887-01 | 70R-20650 | SUMO2 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-102892-01 | 10R-1181 | SUMO2 antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user. | ELISA, IF, WB | 100 ul | |
| Cloud-Clone | T813-126695-01 | PAG152Hu01 | Polyclonal Antibody to Small Ubiquitin Related Modifier Protein 2 (SUMO2) | Rabbit | Polyclonal | Human | WB; IHC; ICC/IF | 100µl | |
| Cloud-Clone | T813-115133-01 | MAG152Hu21 | Monoclonal Antibody to Small Ubiquitin Related Modifier Protein 2 (SUMO2) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| MyBioSource | R247-151478-01 | MBS439221 | SUMO-2 (SUMO2), Monoclonal Antibody | Mouse | Monoclonal | Human, Rat | FC/FACS; IF; Immunohistochemistry (IHC) Formalin | 0.02 mg | |
| MyBioSource | R247-200853-01 | MBS9200437 | SUMO2, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat, Bovine, Monkey, Pig, Hamster, Chicken | IF; ELISA; WB | 0.08 mL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
SUMO1
SUMO is conjugated to E1 (UBA2:SAE1)
UBA2
SUMO is conjugated to E1 (UBA2:SAE1)
SAE1
SUMO is conjugated to E1 (UBA2:SAE1)
PIAS3
SUMOylation of transcription factors
PIAS2
SUMOylation of transcription factors
VDR
Vitamin D (calciferol) metabolism
NUP133
SUMOylation of SUMOylation proteins
NUP62
SUMOylation of SUMOylation proteins