STAT5A — 카탈로그 48건
Gene STAT5A
NCBI Gene 6776
국내 소싱 가능
48건
유전자 개요
STAT5A가 암호화하는 단백질은 전사인자(transcription factor) STAT 계열의 구성원으로, 사이토카인과 성장인자에 반응해 수용체 결합 키나아제(kinase)에 의해 인산화된 뒤 동종 또는 이종 이합체를 형성하고 세포핵으로 이동해 전사 활성화인자로 작용한다. 이 단백질은 IL2, IL3, IL7, GM-CSF, 에리트로포이에틴(erythropoietin), 트롬보포이에틴(thrombopoietin) 및 여러 성장호르몬 등 다양한 리간드의 신호를 매개한다. TEL/JAK2 유전자 융합과 연관된 골수종 및 림프종(lymphoma)에서는 세포 자극과 무관하게 활성화되며, 이러한 활성화가 종양 형성에 필수적인 것으로 밝혀졌다.
Downstream signal transductionErythropoietin activates STAT5Growth hormone receptor signalingInactivation of CSF3 (G-CSF) signalingInterleukin-15 signalingInterleukin-2 signalingInterleukin-20 family signalingInterleukin-21 signalingInterleukin-3, Interleukin-5 and GM-CSF signalingInterleukin-7 signaling
canceracute myeloid leukemiaeosinophil countdermatitiseosinophil percentage of leukocytestriglyceride measurementlow density lipoprotein cholesterol measurementhigh density lipoprotein cholesterol measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B. · Genes Dev (2008)Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation. · Cytokine Growth Factor Rev (1999)Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers. · Int J Cancer (2004)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109622-01 | CSB-RA022814A694phHU | Phospho-STAT5A (Y694) Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, WB, IHC | 50μl, 100μl | |
| MyBioSource | R247-212469-01 | MBS9601879 | STAT5A, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-212291-01 | MBS9601073 | STAT5A/B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-212290-01 | MBS9601072 | STAT5A, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; IP; ELISA | 0.1 mL | |
| Biosynth | F502-105842-01 | 10R-5973 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, WB | 100 ul | |
| Biosynth | F502-105839-01 | 10R-5970 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-134882-01 | 70R-50436 | STAT5A antibody | Rabbit | Polyclonal | Recognizes endogenous levels of STAT5A protein; Cross: Monkey | WB, IHC, IP | 100 ul | |
| Biosynth | F502-132416-01 | 70R-37489 | STAT5A antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-105844-01 | 10R-5975 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-134881-01 | 70R-50435 | STAT5A antibody | Rabbit | Polyclonal | Recognizes endogenous levels of STAT5A protein; Cross: Monkey | WB, IHC, IF, ICC, IP | 100 ul | |
| Biosynth | F502-131969-01 | 70R-37067 | STAT5A antibody (Ser725) | Rabbit | Polyclonal | STAT5A antibody (Ser725) detects endogenous levels of STAT5A only when phosphorylated at serine 725. The antibody will detect species specific phosphorylation as follows: Human: Ser726, Rat: Ser725; Cross: Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-128103-01 | 70R-32520 | STAT5A antibody (Tyr694) | Rabbit | Polyclonal | STAT5A antibody (Tyr694) detects endogenous levels of STAT5A only when phosphorylated at tyrosine 694; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-130595-01 | 70R-35385 | STAT5A antibody | Rabbit | Polyclonal | STAT5A antibody detects endogenous levels of total STAT5A protein; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129143-01 | 70R-33864 | STAT5A/B antibody | Rabbit | Polyclonal | STAT5A/B antibody detects endogenous levels of total STAT5A/B protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-128100-01 | 70R-32518 | STAT5A antibody (Ser780) | Rabbit | Polyclonal | STAT5A antibody (Ser780) detects endogenous levels of STAT5A only when phosphorylated at serine 780; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-105845-01 | 10R-5976 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IHC, WB | 100 ul | |
| Biosynth | F502-134883-01 | 70R-50437 | STAT5A antibody | Rabbit | Polyclonal | Recognizes endogenous levels of STAT5A protein; Cross: Mouse, Rat, Bovine, Pig, Sheep | WB, IF, ICC | 100 ul | |
| Biosynth | F502-105846-01 | 10R-5977 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, WB | 100 ul | |
| Biosynth | F502-132028-01 | 70R-37129 | STAT5A antibody (Tyr694) | Rabbit | Polyclonal | STAT5A antibody (Tyr694) detects endogenous levels of STAT5A only when phosphorylated at tyrosine 694; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-132030-01 | 70R-37130 | STAT5A antibody (Ser780) | Rabbit | Polyclonal | STAT5A antibody (Ser780) detects endogenous levels of STAT5A only when phosphorylated at serine 780; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-105843-01 | 10R-5974 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human, Dog, Rat, Monkey | FC, IF, WB | 100 ul | |
| Biosynth | F502-105841-01 | 10R-5972 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human, Dog, Rat, Monkey | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-132415-01 | 70R-37488 | STAT5A antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-127226-01 | 70R-31716 | STAT5A antibody | Rabbit | Polyclonal | STAT5A antibody detects endogenous levels of total STAT5A protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-105838-01 | 10R-5969 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, WB | 100 ul | |
| Biosynth | F502-128101-01 | 70R-32519 | STAT5A antibody | Rabbit | Polyclonal | STAT5A antibody detects endogenous levels of total STAT5A protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128104-01 | 70R-32521 | STAT5A antibody | Rabbit | Polyclonal | STAT5A antibody detects endogenous levels of total STAT5A protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-123804-01 | 70R-20575 | STAT5A antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-105840-01 | 10R-5971 | STAT5A antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, WB | 100 ul | |
| Cloud-Clone | T813-122116-01 | PAB738Hu01 | KO-Validated Polyclonal Antibody to Signal Transducer And Activator Of Transcription 5A (STAT5A) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| Cloud-Clone | T813-122117-01 | PAB738Hu02 | Polyclonal Antibody to Signal Transducer And Activator Of Transcription 5A (STAT5A) | Rabbit | Polyclonal | Human | WB | 100µl | |
| MyBioSource | R247-193145-01 | MBS838649 | STAT5A, Monoclonal Antibody | Mouse | Monoclonal | Human | FC/FACS; IF; IHC; WB | 0.1 mL | |
| MyBioSource | R247-159739-01 | MBS605235 | STAT 5a,b (STAT5A), Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat, Bovine, Sheep | WB | 0.1 mg | |
| Biosynth | F502-109044-01 | 20R-2231 | STAT5A antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-130670-01 | 70R-35482 | STAT5A antibody | Rabbit | Polyclonal | ELISA, WB, IHC | 0.1 mg | ||
| Biosynth | F502-108732-01 | 20R-1914 | STAT5A antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109043-01 | 20R-2230 | STAT5A antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108733-01 | 20R-1915 | STAT5A antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| MyBioSource | R247-113736-01 | MBS128232 | STAT5A-S780, Antibody | Rabbit | Human | WB | 0.02 mL | ||
| MyBioSource | R247-194169-01 | MBS8509696 | STAT5A, Antibody | Human, Rat | WB; IHC; IF; ELISA | 0.1 mg |