SRC — 카탈로그 38건
Gene SRC
NCBI Gene 6714
국내 소싱 가능
38건
유전자 개요
이 유전자는 닭 육종 바이러스(Rous sarcoma virus)의 v-src 유전자와 매우 유사합니다. 이 원종양유전자(proto-oncogene)는 배아 발달 및 세포 성장 조절에 관여할 수 있습니다. 이 유전자가 암호화하는 단백질은 티로신-단백질 키나아제(tyrosine-protein kinase)이며, c-SRC 키나아제에 의한 인산화(phosphorylation)로 활성이 억제될 수 있습니다. 이 유전자의 돌연변이는 대장암의 악성 진행과 관련될 수 있습니다. 이 유전자에 대해 동일한 단백질을 암호화하는 두 개의 전사체 변이체(transcript variants)가 확인되었습니다.
ADP signalling through P2Y purinoceptor 1Activated NTRK2 signals through FYNActivated NTRK3 signals through PI3KCLEC7A (Dectin-1) signalingCo-inhibition by CTLA4Co-stimulation by CD28Constitutive Signaling by Aberrant PI3K in CancerCyclin D associated events in G1DCC mediated attractive signalingDegradation of CDH1
cancerchronic myelogenous leukemiaactinic keratosisacute lymphoblastic leukemianeoplasmNoonan syndromeRare hemorrhagic disorder due to a constitutional platelet anomalyhypertrophic cardiomyopathy
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Role of Src expression and activation in human cancer. · Oncogene (2000)c-Src and cooperating partners in human cancer. · Cancer Cell (2004)SRC gene expression in human cancer: the role of transcriptional activation. · Biochem Cell Biol (2004)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109616-01 | CSB-RA022650A0HU | SRC Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse | ELISA, WB, IF, FC | 50μl, 100μl | |
| MyBioSource | R247-176336-01 | MBS7114901 | SRC, Recombinant Antibody | Rabbit | Monoclonal | Human, Mouse | ELISA; WB; IF; FC/FACS | 0.05 mL | |
| MyBioSource | R247-212253-01 | MBS9600935 | Src, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-212251-01 | MBS9600933 | Src, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-132074-01 | 70R-37172 | Src antibody (Tyr418) | Rabbit | Polyclonal | Src antibody (Tyr418) detects endogenous levels of Src only when phosphorylated at tyrosine 418; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-132139-01 | 70R-37231 | Src antibody (Tyr529) | Rabbit | Polyclonal | Src antibody (Tyr529) detects endogenous levels of Src only when phosphorylated at tyrosine 529; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-103521-01 | 10R-2138 | SRC antibody | Mouse | Monoclonal | Human | ELISA, WB | 100 ul | |
| Biosynth | F502-117289-01 | 70R-13956 | Src antibody | Rabbit | Polyclonal | Human | WB | 0.1 mg | |
| Biosynth | F502-128088-01 | 70R-32507 | Src antibody | Rabbit | Polyclonal | Src antibody detects endogenous levels of total Src protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-103537-01 | 10R-2154 | SRC antibody | Mouse | Monoclonal | Human | ELISA, WB | 100 ul | |
| Biosynth | F502-132540-01 | 70R-37603 | Src antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-128087-01 | 70R-32506 | Src antibody (Tyr529) | Rabbit | Polyclonal | Src antibody (Tyr529) detects endogenous levels of Src only when phosphorylated at tyrosine 529; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129738-01 | 70R-34409 | Src antibody | Rabbit | Polyclonal | Src antibody detects endogenous levels of total Src protein | WB, ELISA | 0.1 mg | |
| Biosynth | F502-128085-01 | 70R-32504 | Src antibody | Rabbit | Polyclonal | Src antibody detects endogenous levels of total Src protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-132486-01 | 70R-37554 | Src antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB | 0.1 mg | |
| Biosynth | F502-129737-01 | 70R-34408 | Src antibody (Tyr216) | Rabbit | Polyclonal | Src antibody detects endogenous levels of Src only when phosphorylated at tyrosine 216; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-123737-01 | 70R-20514 | SRC antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-128338-01 | 70R-32737 | Src antibody | Rabbit | Polyclonal | Src antibody detects endogenous levels of total Src protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128337-01 | 70R-32736 | Src antibody (Ser75) | Rabbit | Polyclonal | Src antibody detects endogenous levels of Src only when phosphorylated at serine 75; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| MyBioSource | R247-200996-01 | MBS9202232 | Phospho-SRC (Y215), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Chicken, Zebrafish | WB; ELISA | 0.08 mL | |
| MyBioSource | R247-212252-01 | MBS9600934 | Src, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-200835-01 | MBS9200273 | SRC, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse | WB; ELISA; IF | 0.08 mL | |
| MyBioSource | R247-190698-01 | MBS821259 | c-SRC (pY529), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Chicken, Zebrafish | WB; IHC | 0.03 mL | |
| MyBioSource | R247-192458-01 | MBS830900 | SRC, Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA; WB | 0.1 mL | |
| MyBioSource | R247-156616-01 | MBS533137 | SRC, Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA; WB | 0.1 mL | |
| Biosynth | F502-109141-01 | 20R-2336 | Src antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108819-01 | 20R-2005 | Src antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| MyBioSource | R247-193928-01 | MBS850281 | SRC, Antibody | Mouse | Human | WB; ELISA | 0.1 mg | ||
| MyBioSource | R247-194167-01 | MBS850964 | SRC, Antibody | Mouse | Human | WB; ELISA | 0.1 mg | ||
| MyBioSource | R247-212586-01 | MBS9602585 | SRC, Monoclonal Antibody | Mouse | Monoclonal | Human | WB; ELISA | 0.05 mL | |
| ELK Biotechnology | T376-116189-01 | ES1293 | c-Src (phospho Tyr529) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat;Monkey | WB;IHC;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.