SP1 — 카탈로그 20건
Gene SP1
NCBI Gene 6667
국내 소싱 가능
20건
유전자 개요
이 단백질은 다양한 프로모터의 GC가 풍부한 모티프에 결합하는 징크핑거 전사인자(zinc finger transcription factor)이다. 해당 단백질은 세포 분화, 세포 성장, 세포자멸사(apoptosis), 면역 반응, DNA 손상 반응, 염색질(chromatin) 재구성을 포함한 여러 세포 과정에 관여한다. 인산화(phosphorylation), 아세틸화(acetylation), 당화(glycosylation), 단백질 분해 처리와 같은 번역 후 변형은 이 단백질의 활성에 상당한 영향을 미치며, 이 단백질은 활성 인자 또는 억제 인자로 작용할 수 있다. 이 유전자에 대해 서로 다른 아이소폼을 암호화하는 세 가지 전사 변이체가 확인되었다.
Activation of gene expression by SREBF (SREBP)Estrogen-dependent gene expressionNFE2L2 regulating tumorigenic genesOncogene Induced SenescencePPARA activates gene expressionPositive Regulation of CDH1 Gene TranscriptionRNA polymerase II transcribes snRNA genesRegulation of CDH11 gene transcriptionSARS-CoV-1 targets host intracellular signalling and regulatory pathwaysSMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
neurodegenerative diseaseerythrocyte volumesevere acute respiratory syndromeneuroinflammatory disordermean corpuscular hemoglobinmean corpuscular hemoglobin concentrationerythrocyte countreticulocyte count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Regulation of the human SOX9 promoter by Sp1 and CREB. · Exp Cell Res (2007)ZIC2 and Sp3 repress Sp1-induced activation of the human D1A dopamine receptor gene. · J Biol Chem (2000)YY1 and Sp1 transcription factors bind the human transferrin gene in an age-related manner. · J Gerontol A Biol Sci Med Sci (1996)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-215035-01 | MBS9614318 | SP1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep | WB; IF; ICC; EIA | 0.05 mL | |
| Biosynth | F502-130552-01 | 70R-35336 | SP1 antibody | Rabbit | Polyclonal | SP1 antibody detects endogenous levels of total SP1 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132859-01 | 70R-4097 | SP1 antibody | Rabbit | Polyclonal | SP1 antibody was raised against the middle region of SP1; Cross: Human,Mouse,Rat | WB | 100 ul | |
| Biosynth | F502-123683-01 | 70R-20464 | SP1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-131352-01 | 70R-36298 | SP1 antibody (Thr453) | Rabbit | Polyclonal | Human, Mouse, Rat; Cross: Mouse, Rat - Reactive with proteins phosphorylated as follows: Human: Thr453, Mouse: Thr455, Rat: Thr456 | ELISA, IHC, IF, WB | 0.1 mg | |
| Biosynth | F502-128082-01 | 70R-32501 | SP1 antibody (Thr739) | Rabbit | Polyclonal | SP1 antibody (Thr739) detects endogenous levels of SP1 only when phosphorylated at threonine 739; Cross: Mouse, Rat | WB, ELISA | 100 ul | |
| Biosynth | F502-128083-01 | 70R-32502 | SP1 antibody | Rabbit | Polyclonal | SP1 antibody detects endogenous levels of total SP1 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Cloud-Clone | T813-128213-01 | PAM264Hu01 | Polyclonal Antibody to Specificity Protein 1 (Sp1) | Rabbit | Polyclonal | Human | WB; IHC; ICC/IF | 100µl | |
| Biosynth | F502-108443-01 | 20R-1139 | SP1 antibody | Rabbit | Mouse; Cross: Predicted: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit | WB | 100 ul | ||
| Biosynth | F502-108442-01 | 20R-1138 | SP1 antibody | Rabbit | Mouse; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Pig, Rabbit | WB | 100 ul | ||
| Biosynth | F502-108892-01 | 20R-2078 | SP1 antibody | Rabbit | Human; Cross: Human, Rat | WB | 0.05 mg | ||
| MyBioSource | R247-202327-01 | MBS9231652 | SP1, Monoclonal Antibody | Mouse | Monoclonal | Human | WB; IF; FC/FACS; ELISA | ||
| Biosynth | F502-136197-01 | 70R-51639 | SP1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of SP1 protein; Cross: Mouse, Rat, Bovine, Chicken, Monkey | WB, IF, ICC | 100 ul | |
| ELK Biotechnology | T376-121210-01 | ES7256 | Sp1 (phospho Thr453) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-119464-01 | ES3482 | Sp1 rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
EP300
NFE2L2 regulating tumorigenic genes
SMAD3
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SMAD4
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
CREBBP
NFE2L2 regulating tumorigenic genes
RB1
Positive Regulation of CDH1 Gene Transcription
SNAI1
Regulation of CDH11 gene transcription
CDH11
Regulation of CDH11 gene transcription
ILF3
Regulation of CDH11 gene transcription