SIRT3 — 카탈로그 37건

Gene SIRT3 NCBI Gene 23410

취급 제조사 5곳

Cusabio Cloud-Clone MyBioSource ELK Biotechnology Abnova

국내 소싱 가능

37건

유전자 개요

이 유전자는 클래스 III 히스톤 탈아세틸화효소(histone deacetylase) 계열인 시르투인(sirtuin) 단백질의 구성원을 암호화하며, 이는 효모의 Sir2 단백질과 상동성을 가진다. 암호화된 단백질은 미토콘드리아(mitochondria)에만 존재하며, 활성 산소종(reactive oxygen species)을 제거하고 세포자멸사(apoptosis)를 억제하며 암세포(cancer cells) 형성을 막는다. SIRT3는 핵 유전자 발현, 암, 심혈관 질환, 신경 보호, 노화 및 대사 조절에 광범위한 영향을 미친다.

FOXO-mediated transcription of oxidative stress, metabolic and neuronal genesMaturation of TCA enzymes and regulation of TCA cycleMitochondrial unfolded protein response (UPRmt)Regulation of FOXO transcriptional activity by acetylationTranscriptional activation of mitochondrial biogenesis

HbA1c measurementlymphocyte countuterine fibroidplatelet volumeerythrocyte volumeneutrophil percentage of leukocyteslymphocyte percentage of leukocytesRed cell distribution width

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target. · Theranostics (2020)Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis. · Redox Biol (2021)SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth. · EMBO Rep (2023)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-108996-01	CSB-PA882102LA01HU	SIRT3 Antibody	Rabbit	Polyclonal	Human	ELISA, IF	50μg, 100μg
Cloud-Clone	T813-110554-01	LAE913Hu81	FITC-Linked Polyclonal Antibody to Sirtuin 3 (SIRT3)	Rabbit	Antibody labeling	Human	WB; IHC; ICC; IF.	100µl
Cloud-Clone	T813-126152-01	PAE913Mu01	Polyclonal Antibody to Sirtuin 3 (SIRT3)	Rabbit	Polyclonal	Murine	WB; IHC	100µl
Cloud-Clone	T813-114891-01	MAE913Ra21	Monoclonal Antibody to Sirtuin 3 (SIRT3)	Mouse	Monoclonal	Rat	Testing in progress	100µl
Cloud-Clone	T813-126154-01	PAE913Ra01	Polyclonal Antibody to Sirtuin 3 (SIRT3)	Rabbit	Polyclonal	Rat	WB; IHC	100µl
Cloud-Clone	T813-126151-01	PAE913Hu01	Polyclonal Antibody to Sirtuin 3 (SIRT3)	Rabbit	Polyclonal	Human	IHC	100µl
Cloud-Clone	T813-126153-01	PAE913Mu02	Polyclonal Antibody to Sirtuin 3 (SIRT3)	Rabbit	Polyclonal	Murine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-114890-01	MAE913Hu21	Monoclonal Antibody to Sirtuin 3 (SIRT3)	Mouse	Monoclonal	Human	IHC	100µl
MyBioSource	R247-201592-01	MBS9210535	M Sirt3, Polyclonal Antibody	Rabbit	Polyclonal	Mouse, Hamster	WB; ELISA; IHC-P	0.05 mL
MyBioSource	R247-198690-01	MBS9126647	SIRT3, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; IF	0.02 mL
MyBioSource	R247-150324-01	MBS422614	Sirtuin 3 (Sirt3), Polyclonal Antibody	Goat	Polyclonal	Human, Mouse, Rat, Pig	EIA; WB	0.1 mg
MyBioSource	R247-136861-01	MBS2520724	SIRT3, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA; IHC	0.02 mL
MyBioSource	R247-124651-01	MBS2001299	Sirtuin 3 (SIRT3), Monoclonal Antibody	Mouse	Monoclonal	Human, Rat	ICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB	0.1 mL
MyBioSource	R247-118604-01	MBS1492283	NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA; WB; IHC	0.05 mL
MyBioSource	R247-119175-01	MBS1497934	NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA; WB; IHC	0.05 mL
MyBioSource	R247-137186-01	MBS2527671	SIRT3, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA; WB; IHC	0.02 mL
MyBioSource	R247-146494-01	MBS3200907	SIRT3, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Horse	IHC; WB	0.1 mL
ELK Biotechnology	T376-120465-01	ES5340	SIRT3 rabbit pAb	Rabbit	Polyclonal	Human;Mouse;	WB;ELISA	50μL

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cusabio	T094-103670-01	CSB-EL021341HU	Human NAD-dependent deacetylase sirtuin-3, mitochondrial(SIRT3) ELISA kit	Homo sapiens (Human)	ELISA	serum, plasma, tissue homogenates	3.9 pg/mL	96T,5×96T,10×96T
MyBioSource	R247-198036-01	MBS901737	sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) (SIRT3), ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates	Typically less than 3.9 pg/ml.	24-Strip-Wells
MyBioSource	R247-127256-01	MBS2023250	Sirtuin 3 (SIRT3), ELISA Kit	Mouse	ELISA	Mouse tissue homogenates, cell lysates and other biological fluids	< 0.055ng/mL	24-Strip-Wells
MyBioSource	R247-103858-01	MBS047755	Sirtuin 3 (SIRT3), ELISA Kit	Rat	ELISA		0.1ng/ml	48-Strip-Wells
Cloud-Clone	T813-147880-01	SEE913Mu	ELISA Kit for Sirtuin 3 (SIRT3)	Murine	ELISA	tissue homogenates, cell lysates and other biological fluids	0.055ng/mL.	96T
Cloud-Clone	T813-147881-01	SEE913Ra	ELISA Kit for Sirtuin 3 (SIRT3)	Rat	ELISA	tissue homogenates, cell lysates and other biological fluids	0.055ng/mL.	96T
Cloud-Clone	T813-147879-01	SEE913Hu	ELISA Kit for Sirtuin 3 (SIRT3)	Human	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.061ng/mL.	96T

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
MyBioSource	R247-155316-01	MBS515685	SIRT3, Recombinant Protein	Sf9 insect cells using baculovirus		SIRT Assay	0.01 mg
Cloud-Clone	T813-138855-01	RPE913Mu01	Recombinant Sirtuin 3 (SIRT3)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-138854-01	RPE913Hu01	Recombinant Sirtuin 3 (SIRT3)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-138857-01	RPE913Ra01	Recombinant Sirtuin 3 (SIRT3)	E.coli	Rat	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-138856-01	RPE913Mu02	Recombinant Sirtuin 3 (SIRT3)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
MyBioSource	R247-149283-01	MBS388233	SIRT3, Recombinant Protein	E Coli			0.1 mg
Cloud-Clone	T813-100572-01	APE913Ra01	Active Sirtuin 3 (SIRT3)		Rat	Cell culture; Activity Assays.	50µg
Cloud-Clone	T813-100571-01	APE913Mu01	Active Sirtuin 3 (SIRT3)		Murine	Cell culture; Activity Assays.	50µg
Cloud-Clone	T813-100570-01	APE913Hu01	Active Sirtuin 3 (SIRT3)		Human	Cell culture; Activity Assays.	50µg
MyBioSource	R247-117005-01	MBS144309	Sirtuin-3 (SIRT3), Recombinant Protein	E Coli			0.002 mg
Abnova	U731-107077-01	H00023410-P01	SIRT3 (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
Abnova	U731-107078-01	H00023410-Q01	SIRT3 (Human) Recombinant Protein (Q01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re

SIRT3 — 카탈로그 37건

유전자 개요

관련 표적