SFN — 카탈로그 99건
Gene SFN
NCBI Gene 2810
국내 소싱 가능
99건
유전자 개요
SFN은 세포 주기(cell cycle) 체크포인트 단백질을 암호화한다. 이 단백질은 번역(translation) 및 개시 인자(initiation factor)에 결합하여 유사분열(mitosis) 시 번역의 조절자로 기능한다. 또한 DNA 손상에 반응하여 유사분열 과정에서 DNA 오류를 방지하는 역할을 한다.
Activation of BAD and translocation to mitochondria Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complexRHO GTPases activate PKNsRegulation of localization of FOXO transcription factorsSARS-CoV-1 targets host intracellular signalling and regulatory pathwaysSARS-CoV-2 targets host intracellular signalling and regulatory pathwaysTP53 Regulates Metabolic GenesTP53 Regulates Transcription of Genes Involved in G2 Cell Cycle ArrestTranslocation of SLC2A4 (GLUT4) to the plasma membrane
neurodegenerative diseaseCOVID-19severe acute respiratory syndromenon-high density lipoprotein cholesterol measurementmonocyte countlipid measurementbasophil measurementtotal cholesterol measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Sulforaphane - role in aging and neurodegeneration. · Geroscience (2019)Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling. · Cell Death Dis (2023)Small fiber neuropathy: a disabling and underrecognized syndrome. · Curr Opin Pulm Med (2017)
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관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
YWHAZ
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
YWHAQ
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
YWHAG
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
YWHAB
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
YWHAE
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
YWHAH
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
AKT1
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
AKT2
SARS-CoV-2 targets host intracellular signalling and regulatory pathways