해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

RB1 — 카탈로그 30건

Gene RB1 NCBI Gene 5925
취급 제조사 6곳
CusabioMyBioSourceBiosynthCloud-CloneELK BiotechnologyAbnova
국내 소싱 가능
30건

유전자 개요

이 유전자가 지정하는 단백질은 세포 주기(cell cycle)의 음성 조절자이며, 최초로 발견된 종양 억제 유전자(tumor suppressor gene)이다. 또한, 이 단백질은 구성적 이질염색질(constitutive heterochromatin)을 안정화하여 전반적인 염색질(chromatin) 구조를 유지한다. 단백질의 활성형인 저인산화 형태는 전사인자(transcription factor) E2F1에 결합한다.

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1Aberrant regulation of mitotic exit in cancer due to RB1 defectsCondensation of Prophase ChromosomesCyclin A:Cdk2-associated events at S phase entryCyclin D associated events in G1Cyclin E associated events during G1/S transition Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)Defective translocation of RB1 mutants to the nucleusFormation of Senescence-Associated Heterochromatin Foci (SAHF)Inhibition of replication initiation of damaged DNA by RB1/E2F1
retinoblastomahereditary retinoblastomaurinary bladder cancerretinoblastoma (nonhereditary)urinary bladder carcinomasmall cell lung carcinomahepatocellular carcinomalung adenocarcinoma
데이터 출처 · 근거

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

견적제조사Cat NoMfr No제품명HostClonalityReactivityApplicationSize
CusabioT094-109602-01CSB-RA019386A807phHUPhospho-RB1 (S807) Recombinant Monoclonal AntibodyRabbitMonoclonalHumanELISA, IF50μl, 100μl
CusabioT094-109601-01CSB-RA019386A780phHUPhospho-RB1 (S780) Recombinant Monoclonal AntibodyRabbitMonoclonalHumanELISA, IHC, IF, IP50μl, 100μl
MyBioSourceR247-214980-01MBS9614126Retinoblastoma (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, Chicken, HorseWB; IHC; IF; ICC; EIA0.05 mL
MyBioSourceR247-214979-01MBS9614125Retinoblastoma (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, Chicken, HorseWB; IF; ICC; EIA0.05 mL
MyBioSourceR247-215059-01MBS9614399Retinoblastoma (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, HorseWB; IF; ICC; EIA0.05 mL
MyBioSourceR247-214958-01MBS9614058Retinoblastoma (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rabbit, Bovine, Dog, Monkey, Pig, Sheep, Chicken, HorseWB; IF; ICC; EIA0.05 mL
MyBioSourceR247-212041-01MBS9600011Retinoblastoma (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; IF; ICC; ELISA0.1 mL
BiosynthF502-134745-0170R-50311RB1 antibodyRabbitPolyclonalRecognizes endogenous levels of RB1 protein; Cross: Bovine, Dog, PigWB, IHC, IF, ICC100 ul
BiosynthF502-134746-0170R-50312RB1 antibodyRabbitPolyclonalRecognizes endogenous levels of RB1 protein; Cross: Mouse, Rat, Bovine, Dog, PigWB, IHC, IF, ICC, IP100 ul
BiosynthF502-122950-0170R-19793RB1 antibodyRabbitPolyclonalHuman; Cross: Human, MouseELISA, IHC, WB50 ul
Cloud-CloneT813-120805-01PAB211Hu01Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)RabbitPolyclonalHumanICC/IF100µl
Cloud-CloneT813-120806-01PAB211Hu02Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)RabbitPolyclonalHumanWB100µl
MyBioSourceR247-191160-01MBS8242495RB1, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, ChickenWB; IHC; IF; ICC0.03 mL
MyBioSourceR247-125346-01MBS2005835Retinoblastoma Protein 1 (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB0.1 mL
MyBioSourceR247-124322-01MBS194342Retinoblastoma phosphoserine 249/phosphothreonine 252 (RB1), Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, RabbitWestern Blot0.025 mg
MyBioSourceR247-150799-01MBS4380199Rb1, Monoclonal AntibodyMouseMonoclonalHuman, MouseWB; IP; Immunohistochemistry (IHC) Formalin0.02 mg
BiosynthF502-113160-0161-1140Rb1 Antibody (HRP)MouseHuman; Cross: HumanIHC-Fr, WB0.05 mg
ELK BiotechnologyT376-121107-01ES6999Rb (phospho Thr821) rabbit pAbRabbitPolyclonalHuman;Mouse;RatIHC;IF;ELISA50μL
ELK BiotechnologyT376-116534-01ES13455Rb (phospho-Ser807/811) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC50μL
ELK BiotechnologyT376-121705-01ES8829Rb (Acetyl-K873/K874) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC50μL
ELK BiotechnologyT376-118743-01ES20170Rb (Phospho Thr252) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;ELISA;IHC50μL
ELK BiotechnologyT376-121105-01ES6994Rb (phospho Ser811) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC;IF;ELISA50μL
ELK BiotechnologyT376-116664-01ES1401Rb (phospho Ser807) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC;IF;ELISA50μL
ELK BiotechnologyT376-116660-01ES1400Rb (phospho Ser780) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC;IF;ELISA50μL
ELK BiotechnologyT376-121106-01ES6995Rb (phospho Thr826) rabbit pAbRabbitPolyclonalHuman;Mouse;RatWB;IHC;IF;ELISA50μL

관련 표적

같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.

DDX5 Replication of the SARS-CoV-1 genome VHL Replication of the SARS-CoV-1 genome CDK2 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes CCNE1 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes E2F1 Inhibition of replication initiation of damaged DNA by RB1/E2F1 TFDP1 Inhibition of replication initiation of damaged DNA by RB1/E2F1 CDKN1A Formation of Senescence-Associated Heterochromatin Foci (SAHF) CDKN1B Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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