PXDN — 카탈로그 19건
Gene PXDN
NCBI Gene 7837
취급 제조사 4곳
국내 소싱 가능
19건
유전자 개요
이 유전자는 세포외 기질(extracellular matrix)로 분비되는 헴 함유 퍼옥시다아제(heme-containing peroxidase)를 암호화한다. 이는 세포외 기질 형성에 관여하며, 섬유화 신장(fibrotic kidney)에서의 생리적 및 병리적 섬유화 반응(fibrogenic response)에 작용할 수 있다. 이 유전자의 돌연변이는 각막 혼탁(corneal opacification) 및 기타 안구 이상, 그리고 소안구증(microphthalmia) 및 전안부이형성증(anterior segment dysgenesis)을 유발한다.
Crosslinking of collagen fibrilsRegulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
anterior segment dysgenesis 7Congenital cataract microcornea with corneal opacitybody heightlean body massbody composition measurementsitting height measurementrefractive error measurementAbnormality of the skeletal system
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis. · Eur J Hum Genet (2015)Mammalian peroxidasin (PXDN): From physiology to pathology. · Free Radic Biol Med (2022)Peroxidan Plays a Tumor-Promoting Role in Oral Squamous Cell Carcinoma. · Int J Mol Sci (2020)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-124697-01 | MBS2001554 | Peroxidasin Homolog (PXDN), Polyclonal Antibody | Rabbit | Polyclonal | Human | WB; IHC; ICC | 0.1 mL | |
| Cloud-Clone | T813-128175-01 | PAM070Hu01 | Polyclonal Antibody to Peroxidasin Homolog (PXDN) | Rabbit | Polyclonal | Human | WB | 100µl | |
| Cloud-Clone | T813-128176-01 | PAM070Hu02 | Polyclonal Antibody to Peroxidasin Homolog (PXDN) | Rabbit | Polyclonal | Human | ICC/IF | 100µl | |
| MyBioSource | R247-125429-01 | MBS2006478 | Peroxidasin Homolog (PXDN), Polyclonal Antibody | Rabbit | Polyclonal | Human | ICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB | 0.1 mL | |
| MyBioSource | R247-159312-01 | MBS6011940 | PXDN, Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA; WB | 0.1 mg | |
| MyBioSource | R247-124690-01 | MBS2001518 | Peroxidasin Homolog (PXDN), Polyclonal Antibody | Rabbit | Polyclonal | Human | WB; IHC; ICC; IP | 0.1 mL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CDH1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
SOX2
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
ZEB1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
MITF
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
SERPINE1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
EDIL3
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
ITGA2
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
PXN
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition