PTGS2 — 카탈로그 41건
Gene PTGS2
NCBI Gene 5743
취급 제조사 4곳
국내 소싱 가능
41건
유전자 개요
사이클로옥시게나아제(cyclooxygenase)로도 알려진 프로스타글란딘-엔도퍼옥시드 신타아제(prostaglandin-endoperoxide synthase, PTGS)는 프로스타글란딘 생합성 과정의 핵심 효소(enzyme)로서, 다이옥시게나아제(dioxygenase)와 퍼옥시다아제(peroxidase)로 모두 작용합니다. 이 유전자는 염증(inflammation)과 세포분열촉진(mitogenesis)에 관여하는 프로스타노이드 생합성을 담당하며, 특정 자극 사건에 의해 조절되는 유도성 동종효소(inducible isozyme)를 지정합니다.
Biosynthesis of DHA-derived SPMsBiosynthesis of DPAn-3 SPMsBiosynthesis of EPA-derived SPMsBiosynthesis of electrophilic ω-3 PUFA oxo-derivativesInterleukin-10 signalingInterleukin-4 and Interleukin-13 signalingSynthesis of 15-eicosatetraenoic acid derivativesSynthesis of Prostaglandins (PG) and Thromboxanes (TX)
migraine disorderulcerative colitisgoutosteoarthritiscoronary artery diseaseHeadacheDysmenorrhearheumatoid arthritis
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Verification of ferroptosis and pyroptosis and identification of PTGS2 as the hub gene in human coronary artery atherosclerosis. · Free Radic Biol Med (2021)The PTGS2/COX2-PGE(2) signaling cascade in inflammation: Pro or anti? A case study with type 1 diabetes mellitus. · Int J Biol Sci (2023)PTGS2 (Cyclooxygenase-2) expression and survival among colorectal cancer patients: a systematic review. · Cancer Epidemiol Biomarkers Prev (2013)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-110207-01 | CSB-RA920283A0HU | PTGS2 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, WB, IF | 50μl, 100μl | |
| Cusabio | T094-104840-01 | CSB-MA000320 | PTGS2 Monoclonal Antibody | Mouse | Monoclonal | Human,Mouse,Rat | ELISA,IHC | 50μg, 100μg | |
| Cusabio | T094-109590-01 | CSB-RA018986A0HU | PTGS2 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA | 50μl, 100μl | |
| Biosynth | F502-122771-01 | 70R-19628 | PTGS2 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| MyBioSource | R247-210658-01 | MBS9467916 | Cyclooxygenase 2 (Ptgs2), Monoclonal Antibody | Rabbit | Monoclonal | Mouse | WB; IP; ICC | 0.1 mL | |
| MyBioSource | R247-139069-01 | MBS2572532 | Cyclooxygenase 2 (PTGS2), Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | WB; IHC-P | 0.05 mL | |
| MyBioSource | R247-150136-01 | MBS421257 | COX2/PTGS2, Polyclonal Antibody | Goat | Polyclonal | Human, Dog, Pig | EIA; WB | 0.1 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
ALOX15
Biosynthesis of DHA-derived SPMs
ALOX5
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives
ALOX12
Biosynthesis of DHA-derived SPMs
GPX4
Synthesis of 15-eicosatetraenoic acid derivatives
GPX1
Synthesis of 15-eicosatetraenoic acid derivatives
CBR1
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
PTGDS
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
PTGES
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)