PSMC6 — 카탈로그 15건
Gene PSMC6
NCBI Gene 5706
국내 소싱 가능
15건
유전자 개요
26S 프로테아좀(26S proteasome)은 20S 코어(core)와 19S 조절체(regulator)라는 두 개의 복합체로 이루어진 높은 질서를 가진 다중촉매 단백분해효소 복합체이다. 프로테아좀은 진핵세포 전체에 높은 농도(concentration)로 분포하며, 비용소체(non-lysosomal) 경로에서 ATP/유비퀴틴(ubiquitin) 의존적 과정으로 펩타이드를 절단한다. 이 유전자는 샤페론(chaperone)과 유사한 활성을 지닌 AAA 가족 ATPase의 하나인 ATPase 아단위를 암호화하며, 염색체 8번과 12번에서 위유전자(pseudogene)가 확인되었다.
ABC-family proteins mediated transportAMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)APC/C:Cdc20 mediated degradation of SecurinAPC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1AUF1 (hnRNP D0) binds and destabilizes mRNAActivation of NF-kappaB in B cellsAntigen processing: Ubiquitination & Proteasome degradationAssembly of the pre-replicative complexAsymmetric localization of PCP proteinsAutodegradation of Cdh1 by Cdh1:APC/C
HIV infectionsevere acute respiratory syndromeneurodegenerative diseasediastolic blood pressurebody mass indexlysosomal storage diseaseneoplasmglucosamine 6-phosphate N-acetyltransferase measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-106977-01 | CSB-PA018896LA01HU | PSMC6 Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA, WB, IHC | 50μg, 100μg | |
| Biosynth | F502-134709-01 | 70R-50278 | PSMC6 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of PSMC6 protein; Cross: Mouse, Rat, B | WB, IP | 100 ul | |
| Biosynth | F502-122735-01 | 70R-19595 | PSMC6 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-129154-01 | 70R-33874 | PSMC6 antibody | Rabbit | Polyclonal | PSMC6 antibody detects endogenous levels of total PSMC6 protein; Cross: Mouse | WB, ELISA | 0.1 mg | |
| Biosynth | F502-116123-01 | 70R-12798 | PSMC6 antibody | Rabbit | Polyclonal | Human, Mouse | IF, ICC, IHC-P, WB | 100 ul | |
| Cloud-Clone | T813-126732-01 | PAG276Hu01 | Polyclonal Antibody to Proteasome 26S Subunit, ATPase 6 (PSMC6) | Rabbit | Polyclonal | Human | IHC | 100µl | |
| MyBioSource | R247-136724-01 | MBS2517623 | PSMC6, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC | ||
| Biosynth | F502-140549-01 | 70R-9754 | PSMC6 antibody | Rabbit | Polyclonal | Human | WB | 100 ul | |
| ELK Biotechnology | T376-119374-01 | ES3270 | PSMC6 rabbit pAb | Rabbit | Polyclonal | Human;Mouse | WB;IHC | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
PSMA1
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMA3
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMD14
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMC5
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMD13
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMC3
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMD2
Regulation of activated PAK-2p34 by proteasome mediated degradation
PSMA4
Regulation of activated PAK-2p34 by proteasome mediated degradation