해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

PSENEN — 카탈로그 29건

Gene PSENEN NCBI Gene 55851

취급 제조사 3곳

국내 소싱 가능

29건

유전자 개요

프레세닐린은 감마-세크리타제(gamma-secretase) 단백질 복합체의 구성 요소로서, 노치 단백질(Notch proteins) 및 베타-아밀로이드 전구체 단백질(beta-amyloid precursor protein)과 같은 일부 제1형 막관통 단백질의 막내 처리(intramembranous processing)에 필수적입니다. 이 유전자는 노치 경로 신호 전달(Notch pathway signaling)과 감마-세크리타제의 활성 및 축적에 필요한 단백질을 암호화하며, 이 유전자의 반수체 부족(haploinsufficiency)을 초래하는 돌연변이는 가족성 여드름 역행증-2(familial acne inversa-2, ACNINV2)를 유발합니다.

Activated NOTCH1 Transmits Signal to the NucleusAmyloid fiber formationConstitutive Signaling by NOTCH1 HD+PEST Domain MutantsConstitutive Signaling by NOTCH1 PEST Domain MutantsEPH-ephrin mediated repulsion of cellsNOTCH2 Activation and Transmission of Signal to the NucleusNOTCH3 Activation and Transmission of Signal to the NucleusNOTCH4 Activation and Transmission of Signal to the NucleusNRIF signals cell death from the nucleusNoncanonical activation of NOTCH3

hidradenitis suppurativaneurodegenerative diseaseDowling-Degos diseaseAlzheimer diseaseDementiaDesmoid-type fibromatosismathematical abilityeosinophil count

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Low-dose metformin targets the lysosomal AMPK pathway through PEN2. · Nature (2022)Gamma-secretase gene mutations in familial acne inversa. · Science (2010)Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa. · J Clin Invest (2017)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
MyBioSource	R247-160525-01	MBS6133178	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-164145-01	MBS6224067	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	FLISA; WB	0.1 mL
MyBioSource	R247-161484-01	MBS6154390	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-160764-01	MBS6138481	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-164543-01	MBS6234742	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	FLISA; WB	0.1 mL
MyBioSource	R247-161729-01	MBS6159693	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-162944-01	MBS6192042	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	FLISA; WB	0.1 mL
MyBioSource	R247-163340-01	MBS6202717	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	FLISA; WB	0.1 mL
MyBioSource	R247-161007-01	MBS6143784	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-119510-01	MBS151154	PEN2 (PSENEN), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA; WB; IHC; IF	0.1 mg
MyBioSource	R247-163747-01	MBS6213392	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	FLISA; WB	0.1 mL
MyBioSource	R247-154599-01	MBS4763301	PEN2 (PSENEN), Monoclonal Antibody	Rabbit	Monoclonal	Human, Mouse, Rat	WB; IHC-P; ICC; IF; FC/FACS	0.1 mL
MyBioSource	R247-161242-01	MBS6149087	PSENEN, Monoclonal Antibody	Mouse	Monoclonal	Human	ELISA; WB	0.1 mL
MyBioSource	R247-163995-01	MBS622075	Presenilin Enhancer 2 (Psenen), Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA; WB	0.04 mg
MyBioSource	R247-197677-01	MBS9002456	psenen, Polyclonal Antibody	Rabbit	Polyclonal	Zebrafish	ELISA; WB (Western Blot)
Biosynth	F502-140569-01	70R-9774	Psenen antibody	Rabbit	Polyclonal	Mouse; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish	WB	100 ul
Biosynth	F502-140568-01	70R-9773	PSENEN antibody	Rabbit	Polyclonal	Human	WB	100 ul

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
MyBioSource	R247-172798-01	MBS7028058	Gamma-secretase subunit PEN-2 (Psenen), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-175172-01	MBS7100418	Gamma-secretase subunit PEN-2 (PSENEN), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell			0.05 mg
MyBioSource	R247-172794-01	MBS7028054	Gamma-secretase subunit PEN-2 (PSENEN), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-172795-01	MBS7028055	Probable gamma-secretase subunit PEN-2 (psenen), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-172796-01	MBS7028056	Gamma-secretase subunit PEN-2 (PSENEN), Recombinant Protein	Cell Free Expression			0.02 mg
MyBioSource	R247-172797-01	MBS7028057	Gamma-secretase subunit PEN-2 (Psenen), Recombinant Protein	Cell Free Expression			0.02 mg
Abnova	U731-109352-01	H00055851-P01	PSENEN (Human) Recombinant Protein (P01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re
MyBioSource	R247-175139-01	MBS7098248	Gamma-secretase subunit PEN-2 (Psenen), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-175072-01	MBS7093145	Gamma-secretase subunit PEN-2 (psenen), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-174941-01	MBS7082005	Probable gamma-secretase subunit PEN-2 (psenen), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-174939-01	MBS7081797	Gamma-secretase subunit PEN-2 (PSENEN), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell
MyBioSource	R247-175030-01	MBS7089513	Gamma-secretase subunit PEN-2 (Psenen), Recombinant Protein	E Coli or Yeast or Baculovirus or Mammalian Cell

PSENEN — 카탈로그 29건

유전자 개요

관련 표적