PRKDC — 카탈로그 13건
Gene PRKDC
NCBI Gene 5591
국내 소싱 가능
13건
유전자 개요
DNA-의존성 단백질 키나아제(DNA-PK)의 촉매 소단위를 암호화하는 유전자가 PRKDC이다. 이 유전자는 DNA 이중 가닥 절단 복구 및 재조합 과정에서 Ku70/Ku80 이량체 단백질과 함께 기능한다. 이 유전자가 지정하는 단백질은 PI3/PI4-키나아제 계열에 속한다.
Cytosolic sensors of pathogen-associated DNA E3 ubiquitin ligases ubiquitinate target proteinsIRF3-mediated induction of type I IFNNonhomologous End-Joining (NHEJ)
severe combined immunodeficiency due to DNA-PKcs deficiencyneurodegenerative diseasecombined immunodeficiencyCombined immunodeficiencyplatelet countblood sodium bicarbonate amountsitting height measurementbilirubin measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Protection of mammalian telomeres. · Oncogene (2002)DNA damage-induced apoptosis. · Oncogene (2004)Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. · Nature (2011)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109586-01 | CSB-RA018714A2056phHU | Phospho-PRKDC (S2056) Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, IF | 50μl, 100μl | |
| Biosynth | F502-122665-01 | 70R-19530 | PRKDC antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse | ELISA, WB | 50 ul | |
| Biosynth | F502-102585-01 | 10R-10782 | PRKDC antibody | Mouse | Monoclonal | Human | WB, IHC, IF, ELISA | 0.1 mg | |
| Cloud-Clone | T813-127880-01 | PAK362Mu02 | Polyclonal Antibody to Protein Kinase, DNA Activated, Catalytic Polypeptide (PRKDC) | Rabbit | Polyclonal | Murine | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-127879-01 | PAK362Mu01 | Polyclonal Antibody to Protein Kinase, DNA Activated, Catalytic Polypeptide (PRKDC) | Rabbit | Polyclonal | Murine | IHC | 100µl | |
| ELK Biotechnology | T376-121038-01 | ES6804 | DNA-PKCS (phospho Thr2638) rabbit pAb | Rabbit | Polyclonal | Human;Mouse | IF;ELISA | 50μL | |
| ELK Biotechnology | T376-118918-01 | ES2188 | DNA-PKCS rabbit pAb | Rabbit | Polyclonal | Human;Mouse | WB;IHC;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
XRCC6
IRF3-mediated induction of type I IFN
XRCC5
IRF3-mediated induction of type I IFN
TBK1
IRF3-mediated induction of type I IFN
IRF3
IRF3-mediated induction of type I IFN
TREX1
IRF3-mediated induction of type I IFN
IFI16
IRF3-mediated induction of type I IFN
AIM2
Cytosolic sensors of pathogen-associated DNA POLR3A
Cytosolic sensors of pathogen-associated DNA