PDK1 — 카탈로그 29건
Gene PDK1
NCBI Gene 5163
국내 소싱 가능
29건
유전자 개요
피루브산 탈수소효소(PDH)는 피루브산의 산화 탈탄산 반응을 촉매하는 미토콘드리아 내 다중 효소 복합체이며, 포유류 탄수화물 연료 항상성 조절에 주요한 역할을 하는 효소 중 하나이다. 이 유전자는 여러 대체 접합 전사체 변이체가 발견되었다. 특정 피루브산 탈수소효소 키나아제(PDK)에 의한 PDH의 인산화는 불활성화를 초래한다.
Mitochondrial protein degradationRegulation of pyruvate dehydrogenase (PDH) complexSignaling by Retinoic Acid
pyruvate measurementprostate carcinomatriglyceride measurementCrohn's diseasebrain cancerliver disease[Pyruvate dehydrogenase acetyl-transferring] kinase isozyme 1, mitochondrial measurementlevel of oxysterols receptor LXR-beta in blood serum
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. · Cell Metab (2006)HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. · Cell Metab (2006)Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer. · Cells (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-107616-01 | CSB-PA613584LA01HU | PDK1 Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC | 50μg, 100μg | |
| Enzo Life Sciences | R365-100353-01 | ADI-KAP-PK112-D | PDK1 polyclonal antibody | Rabbit | Polyclonal | Dog, Human, Monkey, Mouse, Porcine, Rabbit, Rat | IHC, WB | 50 µg | |
| MyBioSource | R247-212415-01 | MBS9601681 | PDK1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; ELISA | 0.1 mL | |
| Biosynth | F502-102650-01 | 10R-10932 | PDK1 antibody | Mouse | Monoclonal | Human; Cross: Monkey, Rat | ELISA, IHC, IF, FC, WB | 0.1 mg | |
| Biosynth | F502-128206-01 | 70R-32615 | PDK1 antibody (Tyr9) | Rabbit | Polyclonal | PDK1 antibody detects endogenous levels of PDK1 only when phosphorylated at tyrosine 9; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129682-01 | 70R-34358 | PDK1 antibody (Ser241) | Rabbit | Polyclonal | PDK1 antibody detects endogenous levels of PDK1 only when phosphorylated at serine 241; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129683-01 | 70R-34359 | PDK1 antibody | Rabbit | Polyclonal | PDK1 antibody detects endogenous levels of total PDK1 protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-132369-01 | 70R-37445 | PDK1 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC, IF | 0.1 mg | |
| Biosynth | F502-134609-01 | 70R-50187 | PDK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of PDK1 protein | WB | 100 ul | |
| Biosynth | F502-131983-01 | 70R-37087 | PDK1 antibody (Ser241) | Rabbit | Polyclonal | PDK1 antibody (Ser241) detects endogenous levels of PDK1 only when phosphorylated at serine 241; Cross: Mouse, Rat | WB, IHC, IF | 0.1 mg | |
| Biosynth | F502-122289-01 | 70R-19188 | PDK1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Cloud-Clone | T813-124140-01 | PAC718Mu01 | Polyclonal Antibody to Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) | Rabbit | Polyclonal | Murine | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-124141-01 | PAC718Ra01 | Polyclonal Antibody to Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) | Rabbit | Polyclonal | Rat | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-114152-01 | MAC718Ra21 | Monoclonal Antibody to Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) | Mouse | Monoclonal | Rat | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-124139-01 | PAC718Hu01 | Polyclonal Antibody to Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| MyBioSource | R247-137550-01 | MBS2534696 | PDK1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; ELISA | 0.02 mL | |
| MyBioSource | R247-177514-01 | MBS714273 | pyruvate dehydrogenase kinase, isozyme 1 (PDK1), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; WB | 0.1 mL | |
| MyBioSource | R247-135079-01 | MBS244103 | PDK1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Dog, Monkey, Pig | Immunohistochemistry (IHC - Paraffin); WB | 0.05 mg | |
| Biosynth | F502-108699-01 | 20R-1881 | PDK1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-109003-01 | 20R-2190 | PDK1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| Biosynth | F502-136964-01 | 70R-5750 | PDK1 antibody | Rabbit | Polyclonal | PDK1 antibody was raised against the middle region of PDK1; Cross: Human | WB | 100 ul | |
| ELK Biotechnology | T376-119341-01 | ES3168 | PDK1 rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
DLD
Regulation of pyruvate dehydrogenase (PDH) complex
PDHA1
Regulation of pyruvate dehydrogenase (PDH) complex
PDHB
Regulation of pyruvate dehydrogenase (PDH) complex
PDK2
Regulation of pyruvate dehydrogenase (PDH) complex
DLAT
Regulation of pyruvate dehydrogenase (PDH) complex
PDK4
Regulation of pyruvate dehydrogenase (PDH) complex
SIRT4
Regulation of pyruvate dehydrogenase (PDH) complex
RARB
Signaling by Retinoic Acid