PCNA — 카탈로그 40건
Gene PCNA
NCBI Gene 5111
국내 소싱 가능
40건
유전자 개요
이 유전자가 지정하는 단백질은 세포핵(nucleus)에서 발견되며 DNA 중합효소 델타(DNA polymerase delta)의 보조 인자(cofactor)로 작용한다. 암호화된 단백질은 동종 삼량체(homotrimer)로 기능하며 DNA 복제(replication) 중 선도 가닥 합성의 진행성(processivity)을 증가시키는 데 도움을 준다. DNA 손상에 반응하여 이 단백질은 유비퀴틴화(ubiquitination)되고 RAD6 의존적 DNA 복구 경로에 관여한다. 이 유전자에 대해 동일한 단백질을 암호화하는 두 개의 전사체 변이체(transcript variant)가 발견되었다. 이 유전자의 위유전자(pseudogene)는 4번 염색체와 X 염색체에서 기술되었다.
Dual Incision in GG-NERDual incision in TC-NERE3 ubiquitin ligases ubiquitinate target proteinsG1/S-Specific TranscriptionGap-filling DNA repair synthesis and ligation in GG-NERGap-filling DNA repair synthesis and ligation in TC-NERHDR through Homologous Recombination (HRR)Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)PCNA-Dependent Long Patch Base Excision Repair
ataxia-telangiectasia-like disorderbody heightsitting height measurementlean body massbody composition measurementheight growth attributeneurodegenerative diseaseanthropometric measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Human PCNA Structure, Function and Interactions. · Biomolecules (2020)Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells. · Mol Cell (2021)PCNA binding proteins. · Front Biosci (1999)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-109573-01 | CSB-RA017621MA1HU | PCNA Recombinant Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA, FC | 50μl, 100μl | |
| Cusabio | T094-104730-01 | CSB-MA000186 | PCNA Monoclonal Antibody | Mouse | Monoclonal | Human,Mouse,Rat | ELISA,WB,IHC | 50μg, 100μg | |
| Cusabio | T094-106804-01 | CSB-PA01567A0Rb | PCNA Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC, IF | 50μg, 100μg | |
| MyBioSource | R247-214889-01 | MBS9613747 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | EIA | 0.1 mL | |
| MyBioSource | R247-173404-01 | MBS7044279 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB; IHC; IF | 0.05 mg | |
| MyBioSource | R247-138275-01 | MBS2556303 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC | 0.06 mL | |
| MyBioSource | R247-214707-01 | MBS9612794 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | EIA | 0.1 mL | |
| MyBioSource | R247-128898-01 | MBS2032860 | Proliferating Cell Nuclear Antigen (PCNA), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Sheep, Goat, Chicken, Horse | WB; ICC; Immunohistochemistry (IHC) Formalin/Paraffin; ELISA | 0.1 mL | |
| Biosynth | F502-114574-01 | 61R-P152ABT | PCNA antibody (biotin) | Mouse | Polyclonal | Rat; Cross: Human, Mouse, insect, yeast | FC, IHC-F, IHC-P, IP, WB | ||
| Biosynth | F502-102641-01 | 10R-1089 | PCNA antibody | Mouse | Monoclonal | Human; Cross: To be determined by end-user. | ELISA, WB | 100 ul | |
| Biosynth | F502-134599-01 | 70R-50178 | PCNA antibody | Rabbit | Polyclonal | Recognizes endogenous levels of PCNA protein; Cross: Mouse, Rat, Bovine, Chicken, Monkey, Pig | WB, IHC | 100 ul | |
| Biosynth | F502-126138-01 | 70R-30716 | PCNA antibody | Rabbit | Polyclonal | PCNA antibody detects endogenous levels of total PCNA protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-134600-01 | 70R-50179 | PCNA antibody | Rabbit | Polyclonal | Recognizes endogenous levels of PCNA protein; Cross: Mouse, Rat, Bovine, Chicken, Dog, Monkey, Pig, Rabbit | WB, IF, ICC | 100 ul | |
| Biosynth | F502-106377-01 | 10R-6773 | PCNA antibody | Mouse | Monoclonal | Human, Mouse, Rat, Insect, Yeast | IHC, ICC, WB | 1 ml | |
| Biosynth | F502-122251-01 | 70R-19153 | PCNA antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat, ZebraFish | ELISA, IHC, IF, WB | 50 ul | |
| Biosynth | F502-106332-01 | 10R-6674 | PCNA antibody | Mouse | Monoclonal | Human | Functional Assay | 0.025 mg, 0.1 mg | |
| Cloud-Clone | T813-112197-01 | MAA591Hu21 | Monoclonal Antibody to Proliferating Cell Nuclear Antigen (PCNA) | Mouse | Monoclonal | Human | WB; IHC; ICC/IF | 100µl | |
| Cloud-Clone | T813-118949-01 | PAA591Hu01 | Polyclonal Antibody to Proliferating Cell Nuclear Antigen (PCNA) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| Cloud-Clone | T813-118950-01 | PAA591Mi01 | Polyclonal Antibody to Proliferating Cell Nuclear Antigen (PCNA) | Rabbit | Polyclonal | Monkey | WB; IHC | 100µl | |
| MyBioSource | R247-154353-01 | MBS475080 | PCNA, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat, Monkey, Hamster | WB; IP; ICC; IHC | 0.1 mL | |
| MyBioSource | R247-112711-01 | MBS125201 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC-P; IF; ICC; ELISA | 0.02 mL | |
| MyBioSource | R247-190646-01 | MBS820966 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Monkey, Pig, Chicken | WB; IF; ICC | 0.03 mL | |
| Biosynth | F502-106794-01 | 10R-7894 | PCNA antibody | Mouse | Monoclonal | WB, IHC-P, IHC-F, ICC | 0.1 mg | ||
| Biosynth | F502-108592-01 | 20R-1298 | PCNA antibody | Rabbit | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Zebrafish | IHC, WB | 100 ul | ||
| MyBioSource | R247-146132-01 | MBS311679 | Proliferating Cell Nuclear Antigen (PCNA), Monoclonal Antibody | Mouse | Monoclonal | Human | 0.1 mg | ||
| MyBioSource | R247-154364-01 | MBS475120 | PCNA, Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat, Monkey, Hamster | WB; IP; ICC | 0.1 mL | |
| MyBioSource | R247-146117-01 | MBS311430 | Proliferating Cell Nuclear Antigen (PCNA), Monoclonal Antibody | Mouse | Monoclonal | Human | 0.1 mL | ||
| MyBioSource | R247-202351-01 | MBS9231806 | PCNA, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Monkey, Hamster, Chicken | WB; Immunohistochemistry (IHC) Paraffin; IF; FC/FACS; ELISA | ||
| MyBioSource | R247-134873-01 | MBS240535 | PCNA / Cyclin, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Dog, Monkey, Chicken | Immunohistochemistry (IHC - Paraffin); WB; ELISA | ||
| ELK Biotechnology | T376-121714-01 | ES8839 | PCNA rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;ELISA;IHC | 50μL | |
| Biosynth | F502-141340-01 | 75R-1016 | PCNA antibody (Prediluted for IHC) | Mouse | Human, Mouse, Rat, Insect, Yeast | IHC | 7 ml |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
RPA1
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
RPA2
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
UBB
Translesion synthesis by REV1
LIG1
Processive synthesis on the lagging strand
ACD
Telomere C-strand (Lagging Strand) Synthesis
POT1
Telomere C-strand (Lagging Strand) Synthesis
TERF1
Telomere C-strand (Lagging Strand) Synthesis
TINF2
Telomere C-strand (Lagging Strand) Synthesis