PAK2 — 카탈로그 24건
Gene PAK2
NCBI Gene 5062
국내 소싱 가능
24건
유전자 개요
이 유전자 산물은 세포골격 재정렬과 핵 신호 전달을 연결하는 Rho GTPases의 핵심 조절 인자인 p21 활성화 키나아제(PAK) 계열의 세린/트레오닌 키나아제입니다. 이 단백질은 작은 GTP 결합 단백질인 CDC42와 RAC1의 표적이 되며, 광범위한 생물학적 활동에 관여합니다. 이 유전자가 암호화하는 단백질은 카스파제 매개 세포자멸사 과정에서 단백질 분해 절단을 통해 활성화되며, 세포 사멸 조절에 역할을 할 수 있습니다.
Activation of RAC1CD209 (DC-SIGN) signalingCD28 dependent Vav1 pathwayCDC42 GTPase cycleEphrin signalingFCERI mediated MAPK activationGene and protein expression by JAK-STAT signaling after Interleukin-12 stimulationGeneration of second messenger moleculesMAPK6/MAPK4 signalingNef and signal transduction
lymphocyte countleukocyte quantityKnobloch syndromemonocyte countneutrophil countHbA1c measurementerythrocyte volumeplatelet crit
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) EGFR activation limits the response of liver cancer to lenvatinib. · Nature (2021)Progressive Cellular Senescence Mediates Renal Dysfunction in Ischemic Nephropathy. · J Am Soc Nephrol (2021)CDK12 and PAK2 as novel therapeutic targets for human gastric cancer. · Theranostics (2020)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-110021-01 | CSB-RA592787A0HU | PAK2 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human, Mouse, Rat | ELISA, WB, FC, IP | 50μl, 100μl | |
| MyBioSource | R247-127950-01 | MBS2026762 | p21 Protein Activated Kinase 2 (PAK2), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; ICC; Immunohistochemistry (IHC) Formalin/Paraffin; ELISA | 0.1 mL | |
| MyBioSource | R247-214658-01 | MBS9612560 | PAK2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; EIA | 0.1 mL | |
| MyBioSource | R247-119503-01 | MBS151095 | PAK2, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; WB; IHC; IF | 0.1 mg | |
| Biosynth | F502-128306-01 | 70R-32708 | PAK2 antibody | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of total PAK2 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-128303-01 | 70R-32705 | PAK2 antibody (Ser192) | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of PAK2 only when phosphorylated at serine 192; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-127000-01 | 70R-31505 | PAK2 antibody (Ser20) | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of PAK2 only when phosphorylated at serine 20; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-127001-01 | 70R-31506 | PAK2 antibody | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of total PAK2 protein; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128307-01 | 70R-32709 | PAK2 antibody (Ser197) | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of PAK2 only when phosphorylated at serine 197; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-128309-01 | 70R-32710 | PAK2 antibody | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of total PAK2 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-134588-01 | 70R-50168 | PAK2 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of PAK2 protein; Cross: Mouse, Rat, Rabbit | WB | 100 ul | |
| Biosynth | F502-128304-01 | 70R-32706 | PAK2 antibody | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of total PAK2 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-103203-01 | 10R-1807 | PAK2 antibody | Mouse | Monoclonal | Human, Monkey | ELISA, IF, IHC, WB | 100 ul | |
| Biosynth | F502-122191-01 | 70R-19097 | PAK2 antibody | Rabbit | Polyclonal | Human; Cross: Human | ELISA, IHC, IF, WB | 50 ul | |
| Biosynth | F502-128305-01 | 70R-32707 | PAK2 antibody (Ser141) | Rabbit | Polyclonal | PAK2 antibody detects endogenous levels of PAK2 only when phosphorylated at serine 141; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Cloud-Clone | T813-127269-01 | PAH468Hu01 | KO-Validated Polyclonal Antibody to p21 Protein Activated Kinase 2 (PAK2) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| MyBioSource | R247-119112-01 | MBS1497290 | Serine/threonine-protein kinase PAK 2 (PAK2), Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB; IHC | 0.05 mL | |
| MyBioSource | R247-194161-01 | MBS850957 | PAK2, Antibody | Mouse | Human, Monkey | WB; IHC; IF; ELISA | 0.1 mg | ||
| ELK Biotechnology | T376-120916-01 | ES6467 | PAKγ (phospho Ser192) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;ELISA | 50μL | |
| ELK Biotechnology | T376-120917-01 | ES6469 | PAKγ (phospho Ser20) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC;IF;ELISA | 50μL | |
| MyBioSource | R247-154491-01 | MBS475928 | PAK2, Monoclonal Antibody | Mouse | Monoclonal | Human | WB | 0.1 mL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.