NOTCH2 — 카탈로그 56건

Gene NOTCH2 NCBI Gene 4853

취급 제조사 6곳

Cusabio MyBioSource Biosynth Cloud-Clone ELK Biotechnology Abnova

국내 소싱 가능

56건

유전자 개요

NOTCH2는 노치(Notch) 계열에 속하는 1형 막관통 단백질을 암호화하며, 여러 표피성장인자 유사 반복(epidermal growth factor-like repeat)으로 이루어진 세포외 도메인과 여러 종류의 세포내 도메인을 특징으로 한다. 노치 계열 단백질은 세포 운명 결정을 조절함으로써 다양한 발생 과정에 관여하는데, 노치 신호전달은 진화적으로 보존된 세포 간 신호전달 경로로서 인접한 세포 사이의 상호작용을 조절한다. NOTCH2가 암호화하는 단백질은 트랜스골지망(trans-Golgi network)에서 절단되어 이종이량체(heterodimer)로 세포 표면에 제시되며, 막 결합 리간드의 수용체로 기능하면서 혈관·신장·간 발생에 관여할 수 있고, 서로 다른 아이소폼을 암호화하는 두 가지 전사체 변이가 보고되었다.

Defective LFNG causes SCDO3NOTCH2 Activation and Transmission of Signal to the NucleusNOTCH2 intracellular domain regulates transcriptionNOTCH4 Intracellular Domain Regulates TranscriptionNotch-HLH transcription pathwayPre-NOTCH Processing in GolgiPre-NOTCH Processing in the Endoplasmic ReticulumPre-NOTCH Transcription and Translation

acroosteolysis dominant typeAlagille syndrome due to a NOTCH2 point mutationAlagille syndromediffuse large B-cell lymphomaneutrophil countmonocyte counteosinophil countdiabetes mellitus

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis. · Cell (2018)Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. · Cell (2018)Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification. · Hum Mutat (2019)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-106816-01	CSB-PA015950LA01HU	NOTCH2 Antibody	Rabbit	Polyclonal	Human	ELISA, IHC, IF	50μg, 100μg
MyBioSource	R247-119781-01	MBS1564441	NOTCH2 & NOTCH3, Monoclonal Antibody	Human	Monoclonal	Human	FC/FACS/FCM	0.05 mg
Biosynth	F502-134559-01	70R-50140	NOTCH2 antibody	Rabbit	Polyclonal	Recognizes endogenous levels of NOTCH2 protein; Cross: Mouse, Rat	WB	100 ul
Biosynth	F502-126217-01	70R-30788	NOTCH2 antibody	Rabbit	Polyclonal	NOTCH2 antibody detects endogenous levels of fragment of activated NOTCH2 resulting from cleavage adjacent to Val1697; Cross: Mouse, Rat	WB, ELISA	0.1 mg
Biosynth	F502-134557-01	70R-50139	NOTCH2 antibody	Rabbit	Polyclonal	Recognizes endogenous levels of NOTCH2 protein; Cross: Rat	WB, IHC	100 ul
Biosynth	F502-126215-01	70R-30786	NOTCH2 antibody	Rabbit	Polyclonal	NOTCH2 antibody detects endogenous levels of fragment of activated NOTCH2 resulting from cleavage adjacent to Ala1734; Cross: Mouse, Rat	WB, ELISA	0.1 mg
Biosynth	F502-126549-01	70R-31091	Notch 2 antibody	Rabbit	Polyclonal	Notch 2 antibody detects endogenous levels of fragment of activated Notch 2 resulting from cleavage adjacent to Asp1733; Cross: Mouse, Rat	WB, IHC, ELISA	0.1 mg
Cloud-Clone	T813-127958-01	PAL148Hu01	Polyclonal Antibody to Notch Homolog 2 (NOTCH2)	Rabbit	Polyclonal	Human	IHC	100µl
Cloud-Clone	T813-115716-01	MAL148Hu21	Monoclonal Antibody to Notch Homolog 2 (NOTCH2)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-122784-01	MBS1752440	NOTCH2, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; EIA	0.01 mg
MyBioSource	R247-212368-01	MBS9601468	Notch 2 (NOTCH2), Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; IF; ELISA	0.1 mL
ELK Biotechnology	T376-120895-01	ES6408	Cleaved-Notch 2 (V1697) rabbit pAb	Rabbit	Polyclonal	Human;Mouse;Rat	WB;ELISA	50μL
ELK Biotechnology	T376-120894-01	ES6407	Cleaved-Notch 2 (A1734) rabbit pAb	Rabbit	Polyclonal	Human;Mouse;Rat	WB;ELISA	50μL

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
MyBioSource	R247-151975-01	MBS4501417	Notch Homolog 2 (NOTCH2), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates or Other Biological Fluids.	0.33ng/mL	48 Tests
MyBioSource	R247-153618-01	MBS455626	Notch Homolog 2 (NOTCH2), ELISA Kit	Human	ELISA	Human tissue homogenates, cell lysates or other biological fluids	< 0.33ng/mL	48 Tests
MyBioSource	R247-121101-01	MBS1601562	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Rabbit	ELISA	Serum, plasma, cell culture supernates, cell lysates, tissue homogenates	10.19ng/L	48-Strip-Wells
MyBioSource	R247-122213-01	MBS166618	Neurogenic locus notch homolog protein 2, NOTCH2, ELISA Kit	Human	ELISA	Serum, plasma, cell culture supernates, cell lysates, tissue homogenates	0.26ng/ml	48-Strip-Wells
MyBioSource	R247-104521-01	MBS056190	Notch Homolog 2 (NOTCH2), ELISA Kit	Hamster	ELISA		1.0ng/ml	48-Strip-Wells
MyBioSource	R247-144719-01	MBS2886065	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Human	ELISA		0.078ng/mL	48-Strip-Wells
MyBioSource	R247-106430-01	MBS081588	Notch Homolog 2 (NOTCH2), ELISA	Mouse	ELISA		1.0ng/ml	48-Strip-Wells
MyBioSource	R247-197213-01	MBS8806030	NOTCH2 (Notch Homolog 2), ELISA Kit	Human	ELISA		0.31 ng/mL	48-Strip-Wells
MyBioSource	R247-142677-01	MBS2706893	Notch Homolog 2 (NOTCH2), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates and Other Biological Fluids	< 0.31ng/mL	24-Strip-Wells
MyBioSource	R247-126573-01	MBS2019902	Notch Homolog 2 (NOTCH2), ELISA Kit	Human	ELISA	Tissue homogenates, Cell lysates and other biological fluids	0.27ng/mL	24-Strip-Wells
MyBioSource	R247-188006-01	MBS761785	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Human	ELISA	Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples	0.094ng/ml	48-Strip-Wells
Cloud-Clone	T813-149129-01	SEL148Hu	ELISA Kit for Notch Homolog 2 (NOTCH2)	Human	ELISA	tissue homogenates, cell lysates and other biological fluids	0.27ng/mL.	96T
MyBioSource	R247-209336-01	MBS9428341	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Human	ELISA	Serum, plasma, tissue homogenates and other biological fluids.	Less than 0.078ng/mL	96 Tests
MyBioSource	R247-183466-01	MBS7269615	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-109162-01	MBS105415	Notch Homolog 2 (NOTCH2), ELISA Kit	Sheep	ELISA			48-Strip-Wells
MyBioSource	R247-107013-01	MBS089297	Notch Homolog 2 (NOTCH2), ELISA Kit	Bovine	ELISA			48-Strip-Wells
MyBioSource	R247-121055-01	MBS1600997	Neurogenic locus notch homolog protein 2, NOTCH2, ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-107557-01	MBS096068	Notch Homolog 2 (NOTCH2), ELISA Kit	Human	ELISA			48-Strip-Wells
MyBioSource	R247-183444-01	MBS7269280	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Human	ELISA			48-Strip-Wells
MyBioSource	R247-183679-01	MBS7273304	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Hamster	ELISA			48-Strip-Wells
MyBioSource	R247-183550-01	MBS7270962	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Goat	ELISA			48-Strip-Wells
MyBioSource	R247-108882-01	MBS104291	Notch Homolog 2 (NOTCH2), ELISA Kit	Camel	ELISA			48-Strip-Wells
MyBioSource	R247-104790-01	MBS059574	Notch Homolog 2 (NOTCH2), ELISA Kit	Horse	ELISA			48-Strip-Wells
MyBioSource	R247-183513-01	MBS7270291	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Rabbit	ELISA			48-Strip-Wells
MyBioSource	R247-104324-01	MBS053737	Notch Homolog 2 (NOTCH2), ELISA Kit	Monkey	ELISA			48-Strip-Wells
MyBioSource	R247-121002-01	MBS1600120	Neurogenic locus notch homolog protein 2, NOTCH2, ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-105910-01	MBS074224	Notch Homolog 2 (NOTCH2), ELISA Kit	Canine	ELISA			48-Strip-Wells
MyBioSource	R247-106207-01	MBS078333	Notch Homolog 2 (NOTCH2), ELISA Kit	Porcine	ELISA			48-Strip-Wells
MyBioSource	R247-103864-01	MBS047822	Notch Homolog 2 (NOTCH2), ELISA Kit	Rat	ELISA			48-Strip-Wells
MyBioSource	R247-183490-01	MBS7269954	Neurogenic locus notch homolog protein 2 (NOTCH2), ELISA Kit	Mouse	ELISA			48-Strip-Wells
MyBioSource	R247-206740-01	MBS9374193	Notch Homolog 2 (NOTCH2), ELISA Kit	Plant	ELISA
MyBioSource	R247-104971-01	MBS062084	Notch Homolog 2 (NOTCH2), ELISA Kit	Fish	ELISA
MyBioSource	R247-104435-01	MBS055194	Notch Homolog 2 (NOTCH2), ELISA Kit	Goose	ELISA
MyBioSource	R247-104396-01	MBS054633	Notch Homolog 2 (NOTCH2), ELISA Kit	Donkey	ELISA
MyBioSource	R247-107826-01	MBS099737	Notch Homolog 2 (NOTCH2), ELISA Kit	Cat	ELISA
MyBioSource	R247-103836-01	MBS047479	Notch Homolog 2 (NOTCH2), ELISA Kit	Goat	ELISA
MyBioSource	R247-104200-01	MBS052143	Notch Homolog 2 (NOTCH2), ELISA Kit	Chicken	ELISA
MyBioSource	R247-109180-01	MBS105509	Notch Homolog 2 (NOTCH2), ELISA Kit	Duck	ELISA
MyBioSource	R247-108047-01	MBS100866	Notch Homolog 2 (NOTCH2), ELISA Kit	Rabbit	ELISA
MyBioSource	R247-106359-01	MBS080600	Notch Homolog 2 (NOTCH2), ELISA Kit	Cavy	ELISA

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Cloud-Clone	T813-141210-01	RPL148Mu01	Recombinant Notch Homolog 2 (NOTCH2)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-141209-01	RPL148Hu01	Recombinant Notch Homolog 2 (NOTCH2)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Abnova	U731-102421-01	H00004853-Q01	NOTCH2 (Human) Recombinant Protein (Q01)	Wheat Germ (in vitro)	Human	AP,Array,ELISA,WB-Re

NOTCH2 — 카탈로그 56건

유전자 개요

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