NDE1 — 카탈로그 4건
Gene NDE1
NCBI Gene 54820
취급 제조사 2곳
국내 소싱 가능
4건
AURKA Activation by TPX2Amplification of signal from unattached kinetochores via a MAD2 inhibitory signalAnchoring of the basal body to the plasma membraneEML4 and NUDC in mitotic spindle formationLoss of Nlp from mitotic centrosomesLoss of proteins required for interphase microtubule organization from the centrosomeMitotic PrometaphaseRHO GTPases Activate ForminsRecruitment of NuMA to mitotic centrosomesRecruitment of mitotic centrosome proteins and complexes
lissencephaly 4NDE1-related microhydranencephalyaortic aneurysm, familial thoracic 4familial thoracic aortic aneurysm and aortic dissectionmegacystis-microcolon-intestinal hypoperistalsis syndrome 2familial visceral myopathytotal cholesterol measurementaortic aneurysm
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) DISC1, PDE4B, and NDE1 at the centrosome and synapse. · Biochem Biophys Res Commun (2008)16p13.11 microduplication in 45 new patients: refined clinical significance and genotype-phenotype correlations. · J Med Genet (2020)NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness. · Cell Mol Life Sci (2017)
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