MMP19 — 카탈로그 17건
Gene MMP19
NCBI Gene 4327
취급 제조사 4곳
국내 소싱 가능
17건
유전자 개요
이 유전자는 세포외 기질을 분해하는 단백질 계열의 구성원을 암호화한다. 이 단백질은 배아 발달, 생식, 조직 재형성과 같은 정상적인 생리 과정뿐만 아니라 관절염(arthritis) 및 전이(metastasis)와 같은 질병 과정에도 관여한다. 암호화된 단백질은 비활성 프로단백질(proprotein)로 분비되며, 세포외 단백질분해효소(extracellular proteases)에 의한 절단 시 활성화된다. 이 유전자는 대안적 스플라이싱(alternative splicing)을 통해 여러 전사체 변이체(transcript variants)을 생성한다.
Collagen degradationDegradation of the extracellular matrix
Optic neuropathyfamilial cavitary optic disk anomalyneuroinflammatory disorderneurodegenerative diseaseidiopathic pulmonary fibrosisosteonecrosisbody heightprotein measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis. · Am J Respir Cell Mol Biol (2015)Regulation of gene expression by alpha-tocopherol. · Biol Chem (2004)Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo fibroblasts. CMMP, Xenopus XMMP, and human MMP19 have a conserved unique cysteine in the catalytic domain. · J Biol Chem (1998)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-116333-01 | 70R-1300 | MMP19 antibody | Rabbit | Polyclonal | MMP19 antibody was raised against the C terminal of MMP19; Cross: Human | WB, IHC | 100 ul | |
| Biosynth | F502-126758-01 | 70R-31282 | MMP19 antibody | Rabbit | Polyclonal | MMP19 antibody detects endogenous levels of total MMP-19 protein; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-121589-01 | 70R-18546 | MMP19 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-134491-01 | 70R-50079 | MMP19 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of MMP19 protein; Cross: Monkey | WB, IHC | 100 ul | |
| Biosynth | F502-133334-01 | 70R-4600 | MMP19 antibody | Rabbit | Polyclonal | MMP19 antibody was raised against the N terminal of MMP19; Cross: Human,Dog | WB, IHC | 100 ul | |
| Cloud-Clone | T813-122407-01 | PAB853Mu01 | Polyclonal Antibody to Matrix Metalloproteinase 19 (MMP19) | Rabbit | Polyclonal | Murine | WB | 100µl | |
| Cloud-Clone | T813-122408-01 | PAB853Mu02 | Polyclonal Antibody to Matrix Metalloproteinase 19 (MMP19) | Rabbit | Polyclonal | Murine | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-113515-01 | MAB853Hu22 | Monoclonal Antibody to Matrix Metalloproteinase 19 (MMP19) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-122406-01 | PAB853Hu01 | Polyclonal Antibody to Matrix Metalloproteinase 19 (MMP19) | Rabbit | Polyclonal | Human | WB,IHC,ICC/IF | 100µl | |
| MyBioSource | R247-136793-01 | MBS2519194 | MMP19, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; IHC | 0.02 mL | |
| Biosynth | F502-141117-01 | 70R-MR017 | MMP19 antibody | Rabbit | Polyclonal | Human; Cross: To be determined by end - user | IHC, WB | 0.1 mg |