MEF2C — 카탈로그 19건
Gene MEF2C
NCBI Gene 4208
취급 제조사 2곳
국내 소싱 가능
19건
유전자 개요
이 유전자는 근육 형성(myogenesis)에 관여하는 MADS 박스 전사 인핸서 인자 2 (MEF2) 단백질 계열의 구성원을 암호화한다. MEF2 폴리펩타이드 C로 지정된 이 단백질은 전사 활성화 및 DNA 결합 활성을 모두 가진다. 이 단백질은 근육 세포의 분화 상태 유지에 역할을 할 수 있다. 이 유전자의 돌연변이와 결실은 심각한 인지 장애, 고정관념적 운동, 간질, 뇌 기형과 관련이 있다. 대체 접합 전사 변이체들이 기술된 바 있다.
CardiogenesisERK/MAPK targetsExpression of BMAL (ARNTL), CLOCK, and NPAS2Heme signalingMECP2 regulates transcription factorsMyogenesisTranscriptional activation of mitochondrial biogenesis
neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired languageautism spectrum disorder5q14.3 microdeletion syndromeplatelet countplatelet volumeerythrocyte volumemean corpuscular hemoglobingenetic disorder
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) MEF2C silencing downregulates NF2 and E-cadherin and enhances Erastin-induced ferroptosis in meningioma. · Neuro Oncol (2021)MEF2C haploinsufficiency syndrome: Report of a new MEF2C mutation and review. · Eur J Med Genet (2016)MEF2C regulates NK cell effector functions through control of lipid metabolism. · Nat Immunol (2024)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-213707-01 | MBS9607689 | MEF2C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; ELISA | 0.1 mL | |
| MyBioSource | R247-212385-01 | MBS9601562 | MEF2C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IF; ICC; ELISA; ChIP; Immunohistochemistry (IHC) Paraffin; Immunohistochemistry (IHC) Frozen | 0.1 mL | |
| Biosynth | F502-127352-01 | 70R-31830 | MEF2C antibody | Rabbit | Polyclonal | MEF2C antibody detects endogenous levels of total MEF2C protein; Cross: Mouse | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-121508-01 | 70R-18472 | MEF2C antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-129875-01 | 70R-34535 | MEF2C antibody (Ser396) | Rabbit | Polyclonal | MEF2C antibody detects endogenous levels of MEF2C only when phosphorylated at serine 396; Cross: Mouse | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-106564-01 | 10R-7034 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | IF, FC, IHC, WB | 100 ul | |
| Biosynth | F502-104972-01 | 10R-4797 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-104973-01 | 10R-4799 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, WB | 100 ul | |
| Biosynth | F502-106563-01 | 10R-7033 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | IHC, WB | 100 ul | |
| Biosynth | F502-106562-01 | 10R-7031 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | IHC, WB | 100 ul | |
| Biosynth | F502-106561-01 | 10R-7030 | MEF2C antibody | Mouse | Monoclonal | Human; Cross: Human | IHC, WB | 100 ul | |
| Biosynth | F502-131699-01 | 70R-36732 | MEF2C antibody (Ser387) | Rabbit | Polyclonal | Human, Mouse; Cross: Mouse | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129876-01 | 70R-34536 | MEF2C antibody | Rabbit | Polyclonal | MEF2C antibody detects endogenous levels of total MEF2C protein; Cross: Mouse | WB, ELISA | 0.1 mg | |
| MyBioSource | R247-113656-01 | MBS127990 | MEF2C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC | 0.02 mL | |
| Biosynth | F502-108450-01 | 20R-1146 | MEF2C antibody | Rabbit | Human, Mouse; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish | WB | 100 ul | ||
| MyBioSource | R247-112772-01 | MBS125417 | MEF2C-S396, Antibody | Rabbit | Human | WB; IF | 0.02 mL | ||
| MyBioSource | R247-199565-01 | MBS9132282 | MEF2C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB | 0.02 mL | |
| MyBioSource | R247-202441-01 | MBS9232357 | MEF2C, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Pig, Chicken, Zebrafish | WB | 0.08 mL |