해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

MCM2 — 카탈로그 16건

Gene MCM2 NCBI Gene 4171
취급 제조사 4곳
MyBioSourceBiosynthCloud-CloneAbnova
국내 소싱 가능
16건

유전자 개요

이 유전자가 암호화하는 단백질은 진핵생물 게놈 복제(replication) 개시에 관여하는 보존성이 높은 미니 염색체 유지 단백질(mini-chromosome maintenance proteins, MCM) 중 하나입니다. MCM 단백질이 형성하는 육량자 단백질 복합체는 복제 전 복합체(pre-RC)의 핵심 구성 요소이며, 복제 분기점 형성 및 다른 DNA 복제 관련 단백질 모집에 관여할 수 있습니다. 이 단백질은 MCM4, 6, 7과 복합체를 형성하며, 복합체의 헬리카아제(helicase) 활성을 조절하는 것으로 나타났습니다. 이 단백질은 단백질 키나아제 CDC2 및 CDC7에 의해 인산화되어 조절됩니다. 여러 대립유전자 스플라이싱 전사체 변이체가 발견되었으나, 일부 변이체의 전체 길이 특성은 정의되지 않았습니다.

Activation of ATR in response to replication stressActivation of the pre-replicative complexAssembly of the pre-replicative complexOrc1 removal from chromatinRegulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescenceSwitching of origins to a post-replicative stateUnwinding of DNA
autosomal dominant nonsyndromic hearing loss 70platelet volumeautosomal dominant nonsyndromic hearing lossAbnormality of the gastrointestinal tractmetabolite measurementRed cell distribution widthpeak expiratory flowdeafness
데이터 출처 · 근거

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

견적제조사Cat NoMfr No제품명HostClonalityReactivityApplicationSize
MyBioSourceR247-211243-01MBS9504661MCM2, Polyclonal AntibodyRabbitPolyclonalHuman, MouseWB; IHC; IF; ELISA0.05 mL
BiosynthF502-117506-0170R-14187MCM2 antibodyRabbitPolyclonalHumanWB, IHC-P, ICC0.1 mg
BiosynthF502-121474-0170R-18441MCM2 antibodyRabbitPolyclonalHuman; Cross: Human, Mouse, RatELISA, IHC, WB50 ul
BiosynthF502-118965-0170R-1613MCM2 antibodyRabbitPolyclonalMCM2 antibody was raised against the N terminal of MCM2; Cross: HumanWB100 ul
BiosynthF502-134455-0170R-50046MCM2 antibodyRabbitPolyclonalRecognizes endogenous levels of MCM2 proteinWB, IHC, IF, ICC100 ul
BiosynthF502-126745-0170R-31270MCM2 antibodyRabbitPolyclonalMCM2 antibody detects endogenous levels of total MCM2 protein; Cross: Mouse, RatWB, IHC, IF, ELISA0.1 mg
Cloud-CloneT813-113434-01MAB768Hu22Monoclonal Antibody to Minichromosome Maintenance Deficient 2 (MCM2)MouseMonoclonalHumanWB; IHC; ICC; IP.100µl
Cloud-CloneT813-122192-01PAB768Hu01KO-Validated Polyclonal Antibody to Minichromosome Maintenance Deficient 2 (MCM2)RabbitPolyclonalHumanWB; ICC/IF100µl
MyBioSourceR247-207775-01MBS9402256MCM2, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; IHC0.05 mL
MyBioSourceR247-122778-01MBS175236MCM2, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; Immunohistochemistry (IHC) Paraffin; ICC0.01 mg
MyBioSourceR247-113615-01MBS127869MCM2, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; IHC0.02 mL
BiosynthF502-117559-0170R-14248MCM2 antibodyRabbitPolyclonalWB, IHC-P0.1 mg
BiosynthF502-136789-0170R-5571MCM2 antibodyRabbitPolyclonalMCM2 antibody was raised against the middle region of MCM2; Cross: HumanWB100 ul

관련 표적

같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.

MCM5 Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence MCM3 Switching of origins to a post-replicative state MCM7 Switching of origins to a post-replicative state MCM4 Switching of origins to a post-replicative state GMNN Switching of origins to a post-replicative state BRCA1 Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence MITF Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence TERT Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
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