MAX — 카탈로그 18건
Gene MAX
NCBI Gene 4149
취급 제조사 4곳
국내 소싱 가능
18건
유전자 개요
이 유전자가 암호화하는 단백질은 기본 헬릭스-루프-헬릭스 류신 지퍼 (bHLHZ) 전사 인자 계열에 속합니다. 이 단백질은 Mad, Mxi1, Myc와 같은 다른 계열 구성원들과 함께 동종이량체(homodimers) 및 이종이량체(heterodimers)를 형성할 수 있습니다. Myc는 세포 증식, 분화, 세포자멸사에 관여하는 종양 단백질입니다. 호모이합체와 헤테로이합체는 공통 DNA 표적 부위(E box)를 두고 경쟁하며, 이 이합체 형태들 간의 재배열은 복잡한 전사 조절 시스템을 제공합니다. 이 유전자의 돌연변이는 유전성 갈색세포종과 관련이 있는 것으로 보고되었습니다. 이 유전자의 유사유전자는 7번 염색체의 장완에 위치합니다. 대체 스플라이싱을 통해 여러 전사 변이체가 생성됩니다.
Cyclin A:Cdk2-associated events at S phase entryCyclin E associated events during G1/S transition Transcription of E2F targets under negative control by DREAM complexTranscriptional Regulation by E2F6
pheochromocytomahereditary pheochromocytoma-paragangliomaadrenal gland pheochromocytomapolydactyly-macrocephaly syndromehereditary neoplastic syndromeInherited cancer-predisposing syndromeplatelet countbody height
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) MAX and MYC: a heritable breakup. · Cancer Res (2012)Opposite regulation of gene transcription and cell proliferation by c-Myc and Max. · Proc Natl Acad Sci U S A (1993)Soy and Gut Microbiota: Interaction and Implication for Human Health. · J Agric Food Chem (2016)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-173561-01 | MBS7045444 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; IHC; IF | 0.05 mg | |
| MyBioSource | R247-214948-01 | MBS9614035 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Pig, Chicken, Zebrafish, Horse | WB; IHC; IF; ICC; EIA | 0.05 mL | |
| MyBioSource | R247-214962-01 | MBS9614079 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Bovine, Dog, Monkey, Pig, Chicken, Zebrafish, Horse | WB; IHC; EIA | 0.05 mL | |
| Biosynth | F502-103063-01 | 10R-1479 | MAX antibody | Mouse | Monoclonal | Human; Cross: Human. Other species not studied | Dot Blot | 0.1 mg | |
| Biosynth | F502-135824-01 | 70R-51297 | MAX antibody | Rabbit | Polyclonal | Recognizes endogenous levels of MAX protein; Cross: Mouse, Rat, Bovine, Cat | WB | 100 ul | |
| Biosynth | F502-131479-01 | 70R-36461 | MAX antibody | Rabbit | Polyclonal | MAX antibody detects endogenous levels of total MAX protein; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Cloud-Clone | T813-115426-01 | MAH676Hu21 | Monoclonal Antibody to MYC Associated Factor X (MAX) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-127357-01 | PAH676Hu01 | Polyclonal Antibody to MYC Associated Factor X (MAX) | Rabbit | Polyclonal | Human | WB; ICC/IF | 100µl | |
| MyBioSource | R247-192927-01 | MBS835166 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Dog, Chicken, Zebrafish | WB | 0.1 mL | |
| MyBioSource | R247-113682-01 | MBS128060 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF | 0.02 mL | |
| Biosynth | F502-108489-01 | 20R-1191 | MAX antibody | Rabbit | Human, Mouse; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish | WB | 100 ul | ||
| MyBioSource | R247-212838-01 | MBS9603952 | MAX, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; ELISA | 0.1 mL | |
| Biosynth | F502-139269-01 | 70R-8413 | MAX antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Pig, Yeast, Zebrafish | WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
E2F1
Transcription of E2F targets under negative control by DREAM complex
TFDP1
Transcription of E2F targets under negative control by DREAM complex
RBBP4
Transcription of E2F targets under negative control by DREAM complex
MYC
Transcription of E2F targets under negative control by DREAM complex
CDC25A
Transcription of E2F targets under negative control by DREAM complex
AKT1
Cyclin E associated events during G1/S transition AKT2
Cyclin E associated events during G1/S transition CDK2
Cyclin E associated events during G1/S transition