LMNB1 — 카탈로그 12건
Gene LMNB1
NCBI Gene 4001
국내 소싱 가능
12건
유전자 개요
이 유전자는 두 종류의 B형 라민 단백질 중 하나를 지정하며, 핵 라미나(nuclear lamina)의 구성 요소입니다. 이 유전자의 복제는 상염색체 우성 성인 발병 백질이영양증(autosomal dominant adult-onset leukodystrophy, ADLD)과 관련이 있습니다. 대안적 스플라이싱(alternative splicing)을 통해 여러 전사체 변이체(transcript variants)이 생성됩니다.
Breakdown of the nuclear laminaDepolymerization of the Nuclear LaminaDeregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsFormation of Senescence-Associated Heterochromatin Foci (SAHF)Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulationInitiation of Nuclear Envelope (NE) ReformationMeiotic synapsisNuclear Envelope BreakdownRHOD GTPase cycleRHOF GTPase cycle
Autosomal dominant microcephalyAdult-onset autosomal dominant leukodystrophymicrocephaly 26, primary, autosomal dominantadult-onset autosomal dominant demyelinating leukodystrophySyndrome with microcephaly as major featuregenetic disorderbasophil countmean arterial pressure
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. · Cell (2017)Unmasking Transcriptional Heterogeneity in Senescent Cells. · Curr Biol (2017)Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles. · Autophagy (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-104735-01 | CSB-MA000191 | LMNB1 Monoclonal Antibody | Mouse | Monoclonal | Human,Mouse,Rat | ELISA,WB,IP | 50μg, 100μg | |
| Biosynth | F502-121309-01 | 70R-18289 | LMNB1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, IF, WB | 50 ul | |
| Cloud-Clone | T813-115006-01 | MAF548Hu21 | Monoclonal Antibody to Lamin B1 (LMNB1) | Mouse | Monoclonal | Human | WB | 100µl | |
| Cloud-Clone | T813-126431-01 | PAF548Hu01 | Polyclonal Antibody to Lamin B1 (LMNB1) | Rabbit | Polyclonal | Human | WB,IHC | 100µl | |
| Cloud-Clone | T813-126432-01 | PAF548Mi01 | Polyclonal Antibody to Lamin B1 (LMNB1) | Rabbit | Polyclonal | Monkey | WB | 100µl | |
| MyBioSource | R247-158088-01 | MBS570056 | Lamin B1 (LMNB1), Monoclonal Antibody | Mouse | Monoclonal | Human, Mouse, Rat, Rabbit, Bovine, Sheep, Zebrafish, Canine | FC; IHC; WB; ICC; ELISA | 0.1 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
LMNA
Breakdown of the nuclear lamina
CASP6
Breakdown of the nuclear lamina
TMPO
Nuclear Envelope Breakdown
VRK2
Nuclear Envelope Breakdown
VRK1
Nuclear Envelope Breakdown
CDK1
Depolymerization of the Nuclear Lamina
CCNB1
Depolymerization of the Nuclear Lamina
SOD2
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models