해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

IRAK4 — 카탈로그 38건

Gene IRAK4 NCBI Gene 51135
취급 제조사 5곳
CusabioAbbexaMyBioSourceCloud-CloneAbnova
국내 소싱 가능
38건

유전자 개요

이 유전자는 톨 유사 수용체(Toll-like receptor, TLR) 및 T세포 수용체(T-cell receptor, TCR) 신호 전달 경로 모두에서 NF-kappaB를 활성화하는 키나아제(kinase)를 암호화한다. 이 단백질은 대부분의 선천 면역 반응에 필수적이다. 이 유전자의 돌연변이는 IRAK4 결핍증 및 재발성 침습성 폐렴구균 질환을 초래한다. 이 유전자에 대해 서로 다른 아이소폼(isoform)을 암호화하는 여러 전사 변이체(transcript variant)가 발견되었다.

IRAK4 deficiency (TLR2/4)IRAK4 deficiency (TLR5)Interleukin-1 signalingMyD88 cascade initiated on plasma membraneMyD88 dependent cascade initiated on endosomeMyD88:MAL(TIRAP) cascade initiated on plasma membranePI5P, PP2A and IER3 Regulate PI3K/AKT SignalingPIP3 activates AKT signalingTRAF6 mediated IRF7 activation in TLR7/8 or 9 signalingTRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
immunodeficiency 67Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiencyinborn error of immunityneuroinflammatory disorderimmunodeficiency 33pericarditiscongenital dyserythropoietic anemianeurodegenerative disease
데이터 출처 · 근거

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

견적제조사Cat NoMfr No제품명HostClonalityReactivityApplicationSize
CusabioT094-109891-01CSB-RA284992A0HUIRAK4 Recombinant Monoclonal AntibodyRabbitMonoclonalHumanELISA, WB, FC50μl, 100μl
AbbexaF158-106734-01abx145637Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHumanELISA, WB, IHC100 µg
AbbexaF158-100531-01abx011984Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyMouseMonoclonalHuman, Mouse, MonkeyELISA, WB, IHC, FCM100 µl
AbbexaF158-114799-01abx321713Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHumanELISA20 µl
AbbexaF158-119633-01abx431846Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyGoatPolyclonalHumanELISA, WB, IHC, IF/ICC, FCM200 µl
AbbexaF158-100268-01abx004744Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHuman, Mouse, RatELISA, WB, IHC, IF/ICC20 µl
AbbexaF158-111034-01abx234383Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHuman, Mouse, RatELISA, WB100 µg
AbbexaF158-106789-01abx147585Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHuman, RatELISA, WB, IHC, IF/ICC100 µg
AbbexaF158-101350-01abx027074Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHumanELISA, WB80 µl
AbbexaF158-103867-01abx104288Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHumanWB, IHC100 µl
AbbexaF158-114783-01abx321524Interleukin 1 Receptor Associated Kinase 4 (IRAK4) AntibodyRabbitPolyclonalHumanELISA, WB, IP20 µl
MyBioSourceR247-214803-01MBS9613179IRAK4, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rabbit, Bovine, Dog, Pig, Sheep, HorseWB; IF; ICC; EIA0.05 mL
Cloud-CloneT813-121601-01PAB518Ra01Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 4 (IRAK4)RabbitPolyclonalRatWB; IHC; ICC; IP.100µl
Cloud-CloneT813-121600-01PAB518Hu01Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 4 (IRAK4)RabbitPolyclonalHumanWB; IHC100µl
Cloud-CloneT813-113208-01MAB518Hu22Monoclonal Antibody to Interleukin 1 Receptor Associated Kinase 4 (IRAK4)MouseMonoclonalHumanWB; IHC; ICC; IP.100µl
Cloud-CloneT813-113209-01MAB518Ra21Monoclonal Antibody to Interleukin 1 Receptor Associated Kinase 4 (IRAK4)MouseMonoclonalRatWB; IHC; ICC; IP.100µl
MyBioSourceR247-124318-01MBS194277IRAK-4 (IRAK4), Polyclonal AntibodyRabbitPolyclonalHuman, RabbitWestern Blot0.1 mg
MyBioSourceR247-208313-01MBS9410947IRAK4, Polyclonal AntibodyRabbitPolyclonalHumanIHC0.1 mL
MyBioSourceR247-154467-01MBS475631IRAK4, Monoclonal AntibodyMouseMonoclonalHumanWB0.1 mL
MyBioSourceR247-212879-01MBS9604181IRAK4, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; IHC; ELISA0.1 mL
MyBioSourceR247-193971-01MBS8503755IRAK4, Antibody0.1 mg

관련 표적

같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.

MYD88 IRAK4 deficiency (TLR5) IRAK1 MyD88 dependent cascade initiated on endosome TRAF6 MyD88 dependent cascade initiated on endosome IRAK2 MyD88 dependent cascade initiated on endosome TLR5 IRAK4 deficiency (TLR5) TLR9 MyD88 dependent cascade initiated on endosome TLR7 MyD88 dependent cascade initiated on endosome ECSIT TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
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