HNRNPA1 — 카탈로그 15건
Gene HNRNPA1
NCBI Gene 3178
국내 소싱 가능
15건
유전자 개요
HNRNPA1은 이질성 세포핵 리보핵단백질(heterogeneous nuclear ribonucleoprotein, hnRNP) 가족 단백질을 암호화하며, 이 단백질들은 세포핵에서 전구체 mRNA(pre-mRNA)와 결합하여 전구체 mRNA 가공과 mRNA 대사·운반에 영향을 준다. 이 유전자에 의해 만들어지는 단백질은 hnRNP 복합체의 가장 풍부한 핵심 구성 단백질 중 하나로 선택적 스플라이싱(alternative splicing) 조절에 핵심 역할을 한다. 이 유전자의 돌연변이는 근위축성 측삭경화증 20(amyotrophic lateral sclerosis 20) 환자에서 관찰되었고, 게놈 전반에 수많은 위유전자(pseudogene)가 분포되어 있다.
FGFR2 alternative splicingProcessing of Capped Intron-Containing Pre-mRNASARS-CoV-1 modulates host translation machinerySARS-CoV-1-host interactionsmRNA Splicing - Major Pathway
amyotrophic lateral sclerosisinclusion body myopathy with Paget disease of bone and frontotemporal dementiachronic progressive multiple sclerosisFinnish upper limb-onset distal myopathyfamilial amyotrophic lateral sclerosisAmyotrophic lateral sclerosissevere acute respiratory syndromeeosinophil count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization. · Cell (2015)Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins. · Mol Cell (2015)Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. · Nature (2013)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-106534-01 | CSB-PA010600HA01HU | HNRNPA1 Antibody | Rabbit | Polyclonal | Human | ELISA, WB, IHC, IF | 50μg, 100μg | |
| Biosynth | F502-127074-01 | 70R-31575 | hnRNP A1 antibody | Rabbit | Polyclonal | hnRNP A1 antibody detects endogenous levels of total hnRNP A1 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-134244-01 | 70R-49854 | hnRNP A1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of hnRNP A1 protein; Cross: Mouse, Rat, Bovine, Chicken, Monkey, Pig | WB, IHC, IF, ICC, IP | 100 ul | |
| Biosynth | F502-120752-01 | 70R-17772 | HNRNPA1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Cloud-Clone | T813-123395-01 | PAC252Mu01 | Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) | Rabbit | Polyclonal | Murine | WB; IHC; ICC/IF | 100µl | |
| Cloud-Clone | T813-123394-01 | PAC252Hu01 | Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) | Rabbit | Polyclonal | Human | WB; IHC; ICC/IF | 100µl | |
| MyBioSource | R247-190672-01 | MBS821106 | hnRNP A1 (HNRNPA1), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Bovine, Monkey, Pig, Chicken | WB; IHC; IF; ICC; IP | 0.03 mL | |
| Biosynth | F502-109455-01 | 20R-2689 | hnRNP A1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | WB | 0.05 mg | ||
| Biosynth | F502-100797-01 | 10-3044 | hnRNP A1 Antibody | Mouse | Monoclonal | Human | ELISA, ICC/IF, IP, WB | 0.1 mg | |
| Biosynth | F502-100799-01 | 10-3046 | hnRNP A1 Antibody | Mouse | Monoclonal | Human; Cross: Human, Mouse | Flow Cyt, IHC-P, ELISA, WB, IP, ICC/IF | 0.1 mg | |
| Biosynth | F502-100798-01 | 10-3045 | hnRNP A1 Antibody | Mouse | Monoclonal | Human | ELISA, ICC/IF, IP, WB | 0.05 mg | |
| Biosynth | F502-100800-01 | 10-3047 | hnRNP A1 Antibody | Mouse | Monoclonal | Human; Cross: Human, Mouse (IP, WB) | Flow Cyt, IHC-P, ELISA, WB, IP, ICC/IF | 0.05 mg | |
| ELK Biotechnology | T376-119069-01 | ES2544 | hnRNP A1 rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IHC;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.