HNF1A — 카탈로그 27건

Gene HNF1A NCBI Gene 6927

취급 제조사 5곳

Abbexa Cloud-Clone Biosynth MyBioSource Abnova

국내 소싱 가능

27건

유전자 개요

이 유전자가 암호화하는 단백질은 여러 간 특이적 유전자의 발현에 필요한 전사인자(transcription factor)이다. 이 단백질은 동종이량체(homodimer)로 작용하며, 5’-GTTAATNATTAAC-3’ 서열에 결합한다. HNF1A 유전자의 결함은 조기 발현 성인형 당뇨병 3형(MODY3)의 원인이 되며, 간선종(hepatic adenoma)의 발현을 유발할 수도 있다. 대체 스플라이싱(alternative splicing)으로 여러 전사체 변이체(transcript variants)가 생성되어 서로 다른 아이소폼(isoform)을 암호화한다.

Regulation of gene expression in beta cells

MODYtype 2 diabetes mellitusdiabetes mellitusmaturity-onset diabetes of the young type 3hepatocellular adenomatype 1 diabetes mellitusmonogenic diabetesDiabetes mellitus

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Monogenic diabetes: a gateway to precision medicine in diabetes. · J Clin Invest (2021)Reduced penetrance of MODY-associated HNF1A/HNF4A variants but not GCK variants in clinically unselected cohorts. · Am J Hum Genet (2022)Novel insights into genetics and clinics of the HNF1A-MODY. · Endocr Regul (2019)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Abbexa	F158-119775-01	abx433618	Hepatocyte Nuclear Factor 1 Alpha (HNF1A) Antibody	Goat	Polyclonal	Human, Mouse, Rat	ELISA, WB, IHC, IF/ICC	200 µl
Abbexa	F158-109064-01	abx176821	Hepatocyte Nuclear Factor 1 Alpha (HNF1a) Antibody	Rabbit	Polyclonal	Human	WB, IHC, IF/ICC	100 µl
Abbexa	F158-109065-01	abx176822	Hepatocyte Nuclear Factor 1 Alpha (HNF1a) Antibody	Rabbit	Polyclonal	Mouse		100 µl
Cloud-Clone	T813-126982-01	PAG775Mu01	Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Rabbit	Polyclonal	Murine	Testing in progress.	100µl
Cloud-Clone	T813-126983-01	PAG775Mu02	Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Rabbit	Polyclonal	Murine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-115262-01	MAG775Hu21	Monoclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-126981-01	PAG775Hu01	Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Rabbit	Polyclonal	Human	WB; IHC; ICC; IP.	100µl
Biosynth	F502-139904-01	70R-9085	HNF1A antibody	Rabbit	Polyclonal	Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse	WB	100 ul
Biosynth	F502-140358-01	70R-9560	HNF1A antibody	Rabbit	Polyclonal	Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish	WB	100 ul

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Abbexa	F158-111732-01	abx254175	Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) ELISA Kit	Mouse	ELISA	Tissue homogenates, cell lysates and other biological fluids.	4.69 pg/ml	96 tests
Abbexa	F158-107386-01	abx154149	Hepatocyte Nuclear Factor 1 alpha (HNF1a) Antibody	Mouse	ELISA	Tissue homogenates, cell lysates and other biological fluids.	< 0.06 ng/ml	96 tests
Abbexa	F158-111907-01	abx256526	Rat Hepatocyte Nuclear Factor 1 Alpha (HNF1a) ELISA Kit	Rat	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.1 ng/ml	96 tests
Abbexa	F158-107735-01	abx156836	Hepatocyte Nuclear Factor 1 Alpha (HNF1a) Antibody	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	< 0.07 ng/ml	96 tests
MyBioSource	R247-124585-01	MBS2001025	Hepatocyte Nuclear Factor 1	Mouse	CLIA	Tissue homogenates and other biological fluids	5.7pg/mL	24-Strip-Wells
MyBioSource	R247-124545-01	MBS2000824	Hepatocyte Nuclear Factor 1	This assay has high sensitivity and excellent specificity for detection of Hepat	CLIA	Tissue homogenates and other biological fluids	The minimum detectable dose of this kit is typically less than 0.108ng/mL	24-Strip-Wells
MyBioSource	R247-124429-01	MBS2000398	Hepatocyte Nuclear Factor 1	This assay has high sensitivity and excellent specificity for detection of Hepat	CLIA	Tissue homogenates and other biological fluids	The minimum detectable dose of this kit is typically less than 0.068ng/mL	24-Strip-Wells
Cloud-Clone	T813-148431-01	SEG775Hu	ELISA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids	0.061ng/mL.	96T
Cloud-Clone	T813-148432-01	SEG775Mu	ELISA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Murine	ELISA	Tissue homogenates, cell lysates and other biological fluids	0.058ng/mL.	96T

제조사	Cat No	Mfr No	제품명	Expression	Reactivity	Application	Size
Abbexa	F158-123299-01	abx653731	Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) Protein	E. coli	Mouse	WB, SDS-PAGE	10 µg
Abbexa	F158-123298-01	abx653730	Human Hepatocyte Nuclear Factor 1 Alpha (HNF1a) Protein	E. coli	Human	WB, SDS-PAGE	10 µg
Cloud-Clone	T813-140231-01	RPG775Mu01	Recombinant Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	E.coli	Murine	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Cloud-Clone	T813-140230-01	RPG775Hu01	Recombinant Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	E.coli	Human	Positive Control; Immunogen; SDS-PAGE; WB.	50µg
Abnova	U731-104008-01	H00006927-Q01	HNF1A (Human) Recombinant Protein (Q01)		Human	AP,Array,ELISA,WB-Re

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Abbexa	F158-109613-01	abx197139	Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) CLIA Kit	Mouse	CLIA	Tissue homogenates, cell lysates and other biological fluids.	< 5.7 pg/ml	96 tests
Abbexa	F158-120842-01	abx495290	Human Hepatocyte Nuclear Factor 1 Alpha (HNF1a) CLIA Kit	Human	CLIA	Tissue homogenates, cell lysates and other biological fluids.	< 0.058 ng/ml	96 tests
Abbexa	F158-109614-01	abx197140	Rat Hepatocyte Nuclear Factor 1 Alpha (HNF1a) CLIA Kit	Rat	CLIA	Serum, plasma and other biological fluids.	18.8 pg/ml	96 tests
Cloud-Clone	T813-142733-01	SCG775Mu	CLIA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a)	Murine	CLIA	Tissue homogenates and other biological fluids	5.7pg/mL.	96T

HNF1A — 카탈로그 27건

유전자 개요

관련 표적