GRIN2A — 카탈로그 36건

Gene GRIN2A NCBI Gene 2903

취급 제조사 4곳

Cusabio MyBioSource Biosynth Cloud-Clone

국내 소싱 가능

36건

유전자 개요

이 유전자는 글루타메이트(glutamate) 문 게이트 이온 채널 단백질 군의 일원을 암호화한다. 암호화된 단백질은 N-메틸-D-아스파르테이트(N-methyl-D-aspartate, NMDA) 수용체(receptor) 서브유닛으로, NMDA 수용체는 리간드(ligand) 및 전압 의존성이며 장기 강화(long-term potentiation)에 관여한다. 해당 수용체는 칼슘이온에 투과성이 있고 활성화 시 시냅스 후 세포로의 칼슘 유입을 유도하여 여러 신호 전달 경로를 활성화하며, 이 유전자의 손상은 국소 간질 및 인지 장애가 동반되거나 동반되지 않는 언어 장애와 연관된다. 선택적 스플라이싱(alternative splicing)으로 여러 전사체 변이가 생성된다.

Assembly and cell surface presentation of NMDA receptorsLong-term potentiationMECP2 regulates neuronal receptors and channelsNegative regulation of NMDA receptor-mediated neuronal transmissionNeurexins and neuroliginsSynaptic adhesion-like moleculesUnblocking of NMDA receptors, glutamate binding and activation

Landau-Kleffner syndromeRolandic epilepsymajor depressive disorderParkinson diseaseself-limited epilepsy with centrotemporal spikesSeizureCoughearly-onset epileptic encephalopathy and intellectual disability due to GRIN2A mutation

데이터 출처 · 근거

NCBI Gene ↗유전자 정보
Open Targets ↗질환 연관·생물학적 경로
대표 논문 (PubMed) Mapping genomic loci implicates genes and synaptic biology in schizophrenia. · Nature (2022)Rare coding variants in ten genes confer substantial risk for schizophrenia. · Nature (2022)GRIN2A-related disorders: genotype and functional consequence predict phenotype. · Brain (2019)

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

제조사	Cat No	Mfr No	제품명	Host	Clonality	Reactivity	Application	Size
Cusabio	T094-107454-01	CSB-PA14129A0Rb	GRIN2A Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	ELISA, WB, IHC, IF	50μg, 100μg
MyBioSource	R247-213892-01	MBS9608463	GRIN2A, Polyclonal Antibody	Rabbit	Polyclonal	Human, Mouse, Rat	WB; IHC; ELISA	0.1 mL
Biosynth	F502-120570-01	70R-17603	GRIN2A antibody	Rabbit	Polyclonal	Human; Cross: Human, Mouse	ELISA, IF, WB	50 ul
Cloud-Clone	T813-114866-01	MAE806Hu21	Monoclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Mouse	Monoclonal	Human	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-126097-01	PAE806Hu01	Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Rabbit	Polyclonal	Human	WB	100µl
Cloud-Clone	T813-126099-01	PAE806Mu02	Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Rabbit	Polyclonal	Murine	WB; IHC; ICC; IP.	100µl
Cloud-Clone	T813-126098-01	PAE806Mu01	Polyclonal Antibody to Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Rabbit	Polyclonal	Murine	WB; IHC; ICC; IP.	100µl
MyBioSource	R247-171612-01	MBS7001732	Glutamate receptor ionotropic, NMDA 2A (GRIN2A), Polyclonal Antibody	Rabbit	Polyclonal	Human	ELISA; IHC	0.05 mg
MyBioSource	R247-188674-01	MBS800148	GluN2A/NR2A (Grin2a), Monoclonal Antibody	Mouse	Monoclonal	Human, Mouse, Rat	WB; IHC; ICC; IF	0.1 mg
Biosynth	F502-136436-01	70R-5207	GRIN2A antibody	Rabbit	Polyclonal	Human, Rat; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse	WB	100 ul
Biosynth	F502-117801-01	70R-15024	GRIN2A antibody (Tyr1325)	Rabbit	Polyclonal		WB	100 ul
Biosynth	F502-117799-01	70R-15022	GRIN2A antibody	Rabbit	Polyclonal		WB, IHC, IP	0.01 mg
Biosynth	F502-117800-01	70R-15023	GRIN2A antibody (N-terminus)	Rabbit	Polyclonal		WB, IHC	100 ul
MyBioSource	R247-192935-01	MBS835331	GRIN2A, Polyclonal Antibody	Rabbit	Polyclonal		WB	0.1 mL
Biosynth	F502-109570-01	20R-2864	GRIN2A antibody	Rabbit			WB	50 ul

제조사	Cat No	Mfr No	제품명	Reactivity	Application	Sample	Sensitivity	Size
Cloud-Clone	T813-107142-01	KSE806Hu01	ELISA Kit DIY Materials for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.115ng/mL	96T*10
MyBioSource	R247-136610-01	MBS2516108	GRIN2A, ELISA Kit	Human	ELISA	Serum, Plasma, Biological Fluids	Min: 0.188ng/mL; Max: 20ng/mL	24 Tests
MyBioSource	R247-154106-01	MBS459709	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates or Other Biological Fluids.	0.103ng/mL	48 Tests
MyBioSource	R247-139488-01	MBS2602637	Glutamate [NMDA] receptor subunit epsilon-1, GRIN2A, ELISA Kit	Rat	ELISA	Serum, plasma or cell culture supernatant and organizations in the natural and recombinant GRIN2A concentration	0.06 ng/ml.	48-Strip-Wells
MyBioSource	R247-152995-01	MBS451284	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.103ng/mL	48 Tests
MyBioSource	R247-105518-01	MBS068920	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.	0.1ng/ml.	48-Strip-Wells
MyBioSource	R247-142759-01	MBS2707873	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Serum, plasma and other biological fluids	The minimum detectable dose of this kit is typically less than 1.33ng/mL	24-Strip-Wells
MyBioSource	R247-188474-01	MBS765118	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples	0.188ng/ml	48-Strip-Wells
MyBioSource	R247-186697-01	MBS752004	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Porcine	ELISA	Serum, plasma, cell culture supernatants, body fluid and tissue homogenate	0.1 ng/mL	48-Strip-Wells
MyBioSource	R247-196936-01	MBS8802409	GRIN2A (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A), ELISA Kit	Human	ELISA		0.115 ng/mL	48-Strip-Wells
MyBioSource	R247-126922-01	MBS2021633	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Human tissue homogenates, cell lysates, cell culture supernates and other biological fluids	< 0.122ng/mL	24-Strip-Wells
MyBioSource	R247-197294-01	MBS8807208	Anti-GRIN2A (Anti-Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A Antibody), ELISA Kit	Human	ELISA		1.33 ng/mL	48-Strip-Wells
MyBioSource	R247-142545-01	MBS2705633	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Tissue Homogenates, Cell Lysates and Other Biological Fluids	< 0.115ng/mL	24-Strip-Wells
Cloud-Clone	T813-147845-01	SEE806Hu	ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Human	ELISA	tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.122ng/mL.	96T
Cloud-Clone	T813-147846-01	SEE806Mu	ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Murine	ELISA	Tissue homogenates, cell lysates and other biological fluids	0.055ng/mL.	96T
Cloud-Clone	T813-147847-01	SEE806Ra	ELISA Kit for Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A)	Rat	ELISA	Tissue homogenates, cell lysates, cell culture supernates and other biological fluids	0.30ng/mL.	96T
MyBioSource	R247-130583-01	MBS2088058	Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit	Human	ELISA	Tissue homogenates, cell lysates and other biological fluids.	0.115ng/mL	24-Strip-Wells
MyBioSource	R247-131284-01	MBS2097745	Anti-Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A Antibody (Anti-GRIN2A), ELISA Kit	Human	ELISA	Human serum, plasma and other biological fluids	< 1.31ng/mL	24-Strip-Wells

GRIN2A — 카탈로그 36건

유전자 개요

관련 표적