GBP2 — 카탈로그 17건
Gene GBP2
NCBI Gene 2634
국내 소싱 가능
17건
유전자 개요
이 유전자는 구아닌 결합 단백질(GBP) 계열에 속하며, 인터페론(interferon) 유도 단백질들을 포함한다. 이 단백질들은 구아닌 뉴클레오타이드(GMP, GDP, GTP)에 결합할 수 있다. 이 유전자가 지정하는 단백질은 GTPase(GTP 가수분해효소)로서, 주로 GTP를 GDP로 가수분해한다. 또한, 이 단백질은 편평세포암종(squamous cell carcinoma)의 표지자 역할을 할 수 있다.
CASP4 inflammasome assemblyInterferon alpha/beta signalingInterferon gamma signalingMicrobial factors inhibit CASP4 activity
bacterial diseaseneurodegenerative diseaseprotein measurementnonpapillary renal cell carcinomaneoplasmbreast cancergliomacolorectal carcinoma
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms. · Nat Immunol (2020)Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence. · Nature (2017)An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment. · Cancer Commun (Lond) (2022)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-104875-01 | CSB-MA009298A0m | GBP2 Monoclonal Antibody | Mouse | Monoclonal | Human | ELISA, IF,IHC | 50μl, 100μl | |
| Biosynth | F502-132805-01 | 70R-4040 | GBP2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Rat, Cow, Guinea Pig, Rabbit | WB | 100 ul | |
| Biosynth | F502-104560-01 | 10R-4188 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | IF, IHC, WB | 100 ul | |
| Biosynth | F502-104561-01 | 10R-4191 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-104558-01 | 10R-4184 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | IHC, WB | 100 ul | |
| Biosynth | F502-104559-01 | 10R-4186 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-120387-01 | 70R-17437 | GBP2 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-104562-01 | 10R-4192 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-104563-01 | 10R-4193 | GBP2 antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Cloud-Clone | T813-125928-01 | PAE636Ra01 | Polyclonal Antibody to Guanylate Binding Protein 2, Interferon Inducible (GBP2) | Rabbit | Polyclonal | Rat | WB; IHC; ICC; IP. | 100µl | |
| MyBioSource | R247-192529-01 | MBS831365 | GBP2, Monoclonal Antibody | Mouse | Monoclonal | Human | FC/FACS; IF; IHC; WB | 0.1 mL | |
| Biosynth | F502-136939-01 | 70R-5725 | GBP2 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| ELK Biotechnology | T376-114797-01 | ES10690 | GBP2 rabbit pAb | Rabbit | Polyclonal | Human;Rat;Mouse; | WB;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
GBP1
Microbial factors inhibit CASP4 activity
GBP4
Microbial factors inhibit CASP4 activity
CASP4
Microbial factors inhibit CASP4 activity
CALM1
Microbial factors inhibit CASP4 activity
IRF5
Interferon alpha/beta signaling
SOCS3
Interferon alpha/beta signaling
OAS1
Interferon alpha/beta signaling
SOCS1
Interferon alpha/beta signaling