GBP1 — 카탈로그 42건
Gene GBP1
NCBI Gene 2633
국내 소싱 가능
42건
유전자 개요
이 단백질은 인터페론에 의해 발현이 유도된다. Guanylate binding protein은 GMP, GDP, GTP와 같은 구아닌 뉴클레오타이드에 특이적으로 결합하는 능력이 특징이며, 2개의 결합 모티프를 가져 GTP 결합 단백질과 구별된다.
CASP4 inflammasome assemblyInterferon gamma signalingMicrobial factors inhibit CASP4 activity
bacterial diseaseprotein measurementneurodegenerative diseasemuscular diseaseleukocyte quantityNeutrophil inclusion bodiesblood protein amountanthropometric measurement
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms. · Nat Immunol (2020)Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis. · EMBO J (2019)Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence. · Nature (2017)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-120386-01 | 70R-17436 | GBP1 antibody | Rabbit | Polyclonal | Human; Cross: Human | ELISA, IHC, IF, WB | 50 ul | |
| Biosynth | F502-128015-01 | 70R-32436 | GBP1 antibody | Rabbit | Polyclonal | GBP1 antibody detects endogenous levels of total GBP1 protein | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-117409-01 | 70R-14088 | GBP1 antibody | Rabbit | Polyclonal | Human | WB | 0.1 mg | |
| MyBioSource | R247-158844-01 | MBS6005684 | GBP1, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB | 0.2 mL | |
| MyBioSource | R247-119296-01 | MBS1499104 | Interferon-induced guanylate-binding protein 1 (GBP1), Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB; IHC; IP | 0.05 mL | |
| ELK Biotechnology | T376-120523-01 | ES5491 | GBP1 rabbit pAb | Rabbit | Polyclonal | Human;Rat;Mouse; | WB;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
GBP4
Microbial factors inhibit CASP4 activity
GBP2
Microbial factors inhibit CASP4 activity
CASP4
Microbial factors inhibit CASP4 activity
CALM1
Microbial factors inhibit CASP4 activity
IFNG
Interferon gamma signaling
CD44
Interferon gamma signaling
IRF5
Interferon gamma signaling
IFNGR1
Interferon gamma signaling