GATA4 — 카탈로그 22건
Gene GATA4
NCBI Gene 2626
국내 소싱 가능
22건
유전자 개요
이 유전자는 GATA 계열의 아연-인자 전사 인자(transcription factor) 구성원을 암호화한다. 이 계열의 구성원들은 많은 유전자의 프로모터에 존재하는 GATA 모티프를 인식한다. 이 단백질은 배 발생, 심근 분화 및 기능에 관련된 유전자를 조절하며, 정상적인 고환의 발달에 필수적이다. 이 유전자의 돌연변이는 심장 중격 결손과 관련이 있다. 또한, 유전자 발현의 변화는 여러 암종과 관련이 있다. 대안적 스플라이싱은 여러 전사체 변이체를 생성한다.
CardiogenesisDevelopmental Lineage of Multipotent Pancreatic Progenitor CellsDevelopmental Lineage of Pancreatic Acinar CellsDevelopmental Lineage of Pancreatic Ductal CellsFactors involved in megakaryocyte development and platelet productionFormation of definitive endodermFormation of lateral plate mesodermPhysiological factorsSynthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)Transcriptional regulation of testis differentiation
atrial septal defect 2ventricular septal defect 1atrioventricular septal defect 4Tetralogy of Fallot46,XY partial gonadal dysgenesiscongenital heart diseaseneurodegenerative diseasehypertension
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. · Science (2015)METTL3-mediated m(6)A modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progression. · Ann Rheum Dis (2022)Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling. · J Hepatol (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-212293-01 | MBS9601085 | GATA4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| Biosynth | F502-128857-01 | 70R-33603 | GATA4 antibody | Rabbit | Polyclonal | GATA4 antibody detects endogenous levels of total GATA4 protein; Cross: Rat | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-128854-01 | 70R-33600 | GATA4 antibody (Ser262) | Rabbit | Polyclonal | GATA4 antibody detects endogenous levels of GATA4 only when phosphorylated at serine 262; Cross: Mouse, Rat | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-128856-01 | 70R-33602 | GATA4 antibody (Ser105) | Rabbit | Polyclonal | GATA4 antibody detects endogenous levels of GATA4 only when phosphorylated at serine 105; Cross: Mouse | IF, ELISA | 0.1 mg | |
| Biosynth | F502-104546-01 | 10R-4165 | GATA4 antibody | Mouse | Monoclonal | Human; Cross: Human | WB | 100 ul | |
| Biosynth | F502-106352-01 | 10R-6702 | Gata4 antibody | Rat | Monoclonal | Mouse, Human | Functional Assay | 0.025 mg, 0.1 mg | |
| Biosynth | F502-134164-01 | 70R-49781 | GATA4 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of GATA4 protein; Cross: Mouse, Rat, Chicken, Dog, Pig | WB, IHC | 100 ul | |
| Biosynth | F502-128855-01 | 70R-33601 | GATA4 antibody | Rabbit | Polyclonal | GATA4 antibody detects endogenous levels of total GATA4 protein; Cross: Mouse, Rat | WB, IF, ELISA | 0.1 mg | |
| Biosynth | F502-104547-01 | 10R-4166 | GATA4 antibody | Mouse | Monoclonal | Human; Cross: Human | IF, IHC, WB | 100 ul | |
| Biosynth | F502-124863-01 | 70R-21541 | GATA4 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-103208-01 | 10R-1812 | GATA4 antibody | Mouse | Monoclonal | Human; Cross: Human, Mouse | ELISA, WB | 100 ul | |
| Biosynth | F502-127232-01 | 70R-31721 | GATA4 antibody | Rabbit | Polyclonal | GATA4 antibody detects endogenous levels of total GATA4 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Cloud-Clone | T813-118194-01 | PAA374Ra01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | Rabbit | Polyclonal | Rat | IHC | 100µl | |
| Cloud-Clone | T813-118193-01 | PAA374Hu01 | Polyclonal Antibody to GATA Binding Protein 4 (GATA4) | Rabbit | Polyclonal | Human | WB; IHC | 100µl | |
| Biosynth | F502-109480-01 | 20R-2714 | GATA4 antibody | Rabbit | Human, Mouse, Rat | WB | 0.05 mg | ||
| Biosynth | F502-136096-01 | 70R-51546 | GATA4 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of GATA4 protein; Cross: Mouse, Rat, Dog, Pig | WB, IHC, IF, ICC | 100 ul | |
| ELK Biotechnology | T376-120518-01 | ES5483 | GATA-4 (phospho Ser105) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | IHC;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-120517-01 | ES5482 | GATA-4 (phospho Ser262) rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-120519-01 | ES5484 | GATA-4 rabbit pAb | Rabbit | Polyclonal | Human;Mouse;Rat | WB;IF;ELISA | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
SHH
Formation of lateral plate mesoderm
BMP4
Formation of lateral plate mesoderm
IHH
Formation of lateral plate mesoderm
SOX9
Transcriptional regulation of testis differentiation
FOXA2
Formation of definitive endoderm
NPPA
Physiological factors
WWTR1
Physiological factors
CXCR4
Formation of definitive endoderm