ELK1 — 카탈로그 28건
Gene ELK1
NCBI Gene 2002
취급 제조사 3곳
국내 소싱 가능
28건
유전자 개요
ELK1 유전자는 Ets 전사 인자(transcription factor) 패밀리이자 삼항 복합체 인자(ternary complex factor, TCF) 하위 패밀리의 구성원이다. TCF 하위 패밀리 단백질은 c-fos 원종양유전자(proto-oncogene) 프로모터(promoter)에서 세럼 반응 인자(serum response factor) 및 세럼 반응 요소(serum response element)에 결합하여 삼항 복합체를 형성한다. 이 유전자가 암호화하는 단백질은 ras-raf-MAPK 신호 전달 폭포(signaling cascade)의 핵 표적이다. 이 유전자는 대체 번역 개시 코돈(translational start codon) 사용과 대체 스플라이싱(alternative splicing)을 통해 여러 아이소폼(isoform)을 생성한다. 관련 위유전자(pseudogene)가 염색체 7번과 14번에서 확인되었다.
ERK/MAPK targetsEstrogen-dependent nuclear events downstream of ESR-membrane signalingHCMV Early EventsNGF-stimulated transcription
infectious diseaseneoplasmbreast cancerazoospermiacervical cancercolorectal carcinomamale infertility with teratozoospermia due to single gene mutationAlzheimer disease
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Highly-metastatic colorectal cancer cell released miR-181a-5p-rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment. · J Extracell Vesicles (2022)The nuclear factor ID3 endows macrophages with a potent anti-tumour activity. · Nature (2024)Distribution and functional properties of human KCNH8 (Elk1) potassium channels. · Am J Physiol Cell Physiol (2003)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-105690-01 | CSB-PA007603LA01HU | ELK1 Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC | 50μg, 100μg | |
| MyBioSource | R247-173654-01 | MBS7046208 | ELK1, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB; IHC | 0.05 mg | |
| Biosynth | F502-129410-01 | 70R-34109 | Elk1 antibody | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of total Elk1 protein; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132019-01 | 70R-37120 | Elk1 antibody (Thr417) | Rabbit | Polyclonal | Elk1 antibody (Thr417) detects endogenous levels of Elk1 only when phosphorylated at threonine 417; Cross: Mouse, Rat | IHC, IF | 0.1 mg | |
| Biosynth | F502-132017-01 | 70R-37119 | Elk1 antibody (Ser389) | Rabbit | Polyclonal | Elk1 antibody (Ser389) detects endogenous levels of Elk1 only when phosphorylated at serine 389; Cross: Mouse, Rat | IHC | 0.1 mg | |
| Biosynth | F502-103330-01 | 10R-1942 | ELK1 antibody | Mouse | Monoclonal | Human | ELISA, IHC, WB | 100 ul | |
| Biosynth | F502-129409-01 | 70R-34108 | Elk1 antibody (Ser389) | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of Elk1 only when phosphorylated at serine 389; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-127129-01 | 70R-31626 | Elk1 antibody | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of total Elk1 protein; Cross: Mouse, Rat | WB, ELISA | 0.1 mg | |
| Biosynth | F502-129413-01 | 70R-34111 | Elk1 antibody | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of Elk1 protein around Threonine 417; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-134078-01 | 70R-49703 | ELK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ELK1 protein; Cross: Mouse, Rat, Monkey | WB, IHC, IP | 100 ul | |
| Biosynth | F502-132404-01 | 70R-37478 | Elk1 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | IHC | 0.1 mg | |
| Biosynth | F502-131982-01 | 70R-37086 | Elk1 antibody (Ser383) | Rabbit | Polyclonal | Elk1 antibody (Ser383) detects endogenous levels of Elk1 only when phosphorylated at serine 383; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-129407-01 | 70R-34106 | Elk1 antibody (Ser383) | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of Elk1 only when phosphorylated at Serine 383; Cross: Mouse, Rat | WB, IHC, ELISA | 0.1 mg | |
| Biosynth | F502-129408-01 | 70R-34107 | Elk1 antibody | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of Elk1 protein around Serine 383; Cross: Mouse, Rat | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-119993-01 | 70R-17074 | ELK1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-132403-01 | 70R-37477 | Elk1 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | IHC, IF | 0.1 mg | |
| Biosynth | F502-129412-01 | 70R-34110 | Elk1 antibody (Thr417) | Rabbit | Polyclonal | Elk1 antibody detects endogenous levels of Elk1 only when phosphorylated at threonine 417; Cross: Mouse, Rat | IHC, ELISA | 0.1 mg | |
| Biosynth | F502-103331-01 | 10R-1943 | ELK1 antibody | Mouse | Monoclonal | Human | ELISA, WB, | 100 ul | |
| Biosynth | F502-134079-01 | 70R-49704 | ELK1 antibody | Rabbit | Polyclonal | Recognizes endogenous levels of ELK1 protein; Cross: Mouse, Rat, Bovine, Dog, Pig | WB, IHC, IF, ICC | 100 ul | |
| Biosynth | F502-132368-01 | 70R-37444 | Elk1 antibody | Rabbit | Polyclonal | Human; Cross: Mouse, Rat | WB, IHC | 0.1 mg | |
| Biosynth | F502-108722-01 | 20R-1904 | Elk1 antibody | Rabbit | Human; Cross: Human | IHC, WB | 0.05 mg | ||
| Biosynth | F502-108698-01 | 20R-1880 | Elk-1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109002-01 | 20R-2189 | Elk-1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IHC | 0.05 mg | ||
| Biosynth | F502-109034-01 | 20R-2221 | Elk1 antibody | Rabbit | Human; Cross: Human, Mouse, Rat | IF, IHC, WB | 0.05 mg | ||
| MyBioSource | R247-191113-01 | MBS8242039 | ELK1, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IP | 0.03 mL | |
| MyBioSource | R247-112878-01 | MBS125902 | ELK1-S383, Antibody | Rabbit | Human, Mouse, Rat | WB; IHC; IF | 0.02 mL | ||
| Biosynth | F502-117747-01 | 70R-14970 | ELK1 antibody | Rabbit | Polyclonal | WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
MAPK1
ERK/MAPK targets
MAPK3
ERK/MAPK targets
FOS
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
CREB1
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
SRF
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
MAPK14
ERK/MAPK targets
MEF2A
ERK/MAPK targets
MAPK11
ERK/MAPK targets