EIF4B — 카탈로그 18건
Gene EIF4B
NCBI Gene 1975
취급 제조사 3곳
국내 소싱 가능
18건
유전자 개요
이 유전자는 RNA 결합 활성을 부여합니다. 진핵생물 번역 개시 인자 4F 복합체 조립 및 번역 사전조립 복합체 형성에 관여할 것으로 예측됩니다. 이 유전자는 세포질에 위치합니다. 자폐 스펙트럼 장애 및 주요 우울 장애의 바이오마커입니다.
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SDeadenylation of mRNAGTP hydrolysis and joining of the 60S ribosomal subunitL13a-mediated translational silencing of Ceruloplasmin expressionM-decay: degradation of maternal mRNAs by maternally stored factorsRibosomal scanning and start codon recognitionTranslation initiation complex formationZ-decay: degradation of maternal mRNAs by zygotically expressed factorsmTORC1-mediated signalling
neurodegenerative diseaseerythrocyte counttotal cholesterol measurementbody heightserum albumin amountserum alanine aminotransferase amounthematocritmonocyte count
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. · EMBO J (2006)Reprogramming mRNA translation during stress. · Curr Opin Cell Biol (2008)eIF4F: a retrospective. · J Biol Chem (2015)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| MyBioSource | R247-212392-01 | MBS9601579 | EIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC; IF; ICC; ELISA | 0.1 mL | |
| MyBioSource | R247-211213-01 | MBS9503699 | eIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC; IF; ELISA | 0.05 mL | |
| MyBioSource | R247-211173-01 | MBS9502587 | eIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC; IF; ELISA | 0.05 mL | |
| Biosynth | F502-130254-01 | 70R-34968 | eIF4B antibody | Rabbit | Polyclonal | eIF4B antibody detects endogenous levels of total eIF4B protein; Cross: Mouse | WB, IHC, IF, ELISA | 0.1 mg | |
| Biosynth | F502-132306-01 | 70R-37387 | eIF4B antibody (Ser422) | Rabbit | Polyclonal | Human; Cross: Mouse | WB, IHC | 0.1 mg | |
| Biosynth | F502-119974-01 | 70R-17056 | EIF4B antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, WB | 50 ul | |
| Biosynth | F502-133649-01 | 70R-4927 | EIF4B antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit | WB | 100 ul | |
| Biosynth | F502-117499-01 | 70R-1418 | EIF4B antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit | WB, IHC | 100 ul | |
| Biosynth | F502-131649-01 | 70R-36673 | eIF4B antibody (Ser422) | Rabbit | Polyclonal | Human, Mouse, Rat; Cross: Human, Mouse, Rat | WB, IHC, IF, ELISA | 1 mg | |
| MyBioSource | R247-208168-01 | MBS9408587 | EIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF | 0.05 mL | |
| MyBioSource | R247-202055-01 | MBS9217076 | EIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; Immunohistochemistry (IHC) Paraffin; ELISA | 0.08 mL | |
| Biosynth | F502-108969-01 | 20R-2156 | eIF4B antibody | Rabbit | Human; Cross: Human, Mouse | IHC, WB | 0.05 mg | ||
| Biosynth | F502-109431-01 | 20R-2665 | eIF4B antibody | Rabbit | Human; Cross: Human | IHC, WB | 0.05 mg | ||
| MyBioSource | R247-199762-01 | MBS9133346 | EIF4B, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IHC; IF | 0.02 mL | |
| ELK Biotechnology | T376-120728-01 | ES5967 | eIF4B (phospho Ser422) rabbit pAb | Rabbit | Polyclonal | Human;Mouse | WB;IHC;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-120356-01 | ES5075 | eIF4B rabbit pAb | Rabbit | Polyclonal | Human;Mouse | WB;IHC;IF;ELISA | 50μL | |
| ELK Biotechnology | T376-118872-01 | ES20867 | Eif4b Rabbit pAb | Rabbit | Polyclonal | Human; Mouse;Rat | IHC;WB | 50μL |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
EIF4E
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
EIF4A1
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
EIF4A2
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
EIF4EBP1
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
EIF4A3
Z-decay: degradation of maternal mRNAs by zygotically expressed factors
RPS6
mTORC1-mediated signalling
MTOR
mTORC1-mediated signalling
RHEB
mTORC1-mediated signalling