EDIL3 — 카탈로그 29건
Gene EDIL3
NCBI Gene 10085
국내 소싱 가능
29건
유전자 개요
이 유전자가 암호화하는 단백질은 인테그린 리간드(integrin ligand)로, 혈관신생(angiogenesis) 매개에 중요한 역할을 하며 혈관벽 리모델링(vessel wall remodeling) 및 발달에도 관여할 것으로 여겨진다. 또한 내피세포(endothelial cell)의 행동에도 영향을 미친다.
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
metabolite measurementemotional symptom measurementblood protein amountlevel of carnitine O-palmitoyltransferase 1, muscle isoform in blood serumE3 ubiquitin-protein ligase RNF128 measurementamount of granzyme A (human) in bloodn-acetyltransferase 14 measurementlevel of Rap guanine nucleotide exchange factor 1 in blood serum
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) DEL-1 promotes macrophage efferocytosis and clearance of inflammation. · Nat Immunol (2019)A Partial Picture of the Single-Cell Transcriptomics of Human IgA Nephropathy. · Front Immunol (2021)EDIL3 deficiency ameliorates adverse cardiac remodelling by neutrophil extracellular traps (NET)-mediated macrophage polarization. · Cardiovasc Res (2022)
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관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
CDH1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
SOX2
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
ZEB1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
MITF
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
SERPINE1
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
ITGA2
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
PXN
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
PXDN
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition