ECHS1 — 카탈로그 11건
Gene ECHS1
NCBI Gene 1892
국내 소싱 가능
11건
유전자 개요
이 유전자는 미토콘드리아 지방산 베타 산화 경로의 두 번째 단계에서 기능하는 단백질을 지정한다. 이 단백질은 2-trans-enoyl-coenzyme A (CoA) 중간체를 L-3-hydroxyacyl-CoAs로 수화(hydration)시키는 반응을 촉매한다. 이 유전자의 산물은 hydratase/이성질체효소(isomerase) 계열에 속하며, 미토콘드리아 기질에 국소화된다. 문헌에서는 대체 전사(transcription) 개시 부위를 이용하는 전사 변이체들이 보고되었다.
Beta oxidation of butanoyl-CoA to acetyl-CoABeta oxidation of decanoyl-CoA to octanoyl-CoA-CoABeta oxidation of hexanoyl-CoA to butanoyl-CoABeta oxidation of lauroyl-CoA to decanoyl-CoA-CoABeta oxidation of octanoyl-CoA to hexanoyl-CoABranched-chain amino acid catabolismMitochondrial short-chain enoyl-CoA hydratase deficiency 1
mitochondrial short-chain Enoyl-Coa hydratase 1 deficiencygenetic disorderLeigh syndromeneurodegenerative diseaselife span determination traitacisoga measurement(N(1) + N(8))-acetylspermidine measurementblood protein amount
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Lysine catabolism reprograms tumour immunity through histone crotonylation. · Nature (2023)Mendelian etiologies identified with whole exome sequencing in cerebral palsy. · Ann Clin Transl Neurol (2022)Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle. · Nat Commun (2024)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-105674-01 | CSB-PA007382ESR2HU | ECHS1 Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA, WB, IHC | 50μl, 100μl | |
| Cusabio | T094-105673-01 | CSB-PA007382ESR1HU | ECHS1 Antibody | Rabbit | Polyclonal | Human, Mouse | ELISA, WB, IHC | 50μl, 100μl | |
| Biosynth | F502-115636-01 | 70R-1107 | ECHS1 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish | WB | 100 ul | |
| Biosynth | F502-125402-01 | 70R-2490 | ECHS1 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish | WB | 100 ul | |
| Biosynth | F502-119899-01 | 70R-16988 | ECHS1 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| Biosynth | F502-115627-01 | 70R-1098 | ECHS1 antibody | Rabbit | Polyclonal | Human; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish | WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
HADHB
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
BCAT1
Branched-chain amino acid catabolism
BCKDK
Branched-chain amino acid catabolism
ACADSB
Branched-chain amino acid catabolism
DLD
Branched-chain amino acid catabolism
MCCC2
Branched-chain amino acid catabolism
HSD17B10
Branched-chain amino acid catabolism
BCAT2
Branched-chain amino acid catabolism