DPP4 — 카탈로그 43건
Gene DPP4
NCBI Gene 1803
국내 소싱 가능
43건
유전자 개요
DPP4 유전자는 DPP4(dipeptidyl peptidase 4)를 암호화하며, 이는 아데노신 탈아미노효소 복합 단백질-2(adenosine deaminase complexing protein-2) 및 T세포 활성화 항원(T-cell activation antigen) CD26과 동일합니다. 이 단백질은 제2형 막관통 당단백질(transmembrane glycoprotein)로, 폴리펩타이드의 N-말단에서 X-프롤린 이중 펩타이드를 절단하는 세린 외펩타이드 분해효소(serine exopeptidase)입니다. DPP4는 포도당 및 인슐린 대사와 면역 조절에 깊이 관여합니다. 이 단백질은 중동호흡기증후군 코로나바이러스(MERS-CoV)의 기능적 수용체(receptor)로 밝혀졌으며, 단백질 모델링은 이 단백질이 COVID-19를 유발하는 바이러스인 SARS-CoV-2와 유사한 역할을 할 수 있음을 시사합니다.
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
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데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin. · J Invest Dermatol (2018)DPP4 in cardiometabolic disease: recent insights from the laboratory and clinical trials of DPP4 inhibition. · Circ Res (2015)The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation. · Nat Commun (2021)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Cusabio | T094-107373-01 | CSB-PA06229A0Rb | DPP4 Antibody | Rabbit | Polyclonal | Human, Rat | ELISA, WB, IHC, IF | 50μg, 100μg | |
| Cusabio | T094-110216-01 | CSB-RA927191A0HU | DPP4 Recombinant Monoclonal Antibody | Rabbit | Monoclonal | Human | ELISA, IHC | 50μl, 100μl | |
| MyBioSource | R247-175326-01 | MBS7103877 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rat | ELISA; WB; IHC; IF | 0.05 mg | |
| MyBioSource | R247-212776-01 | MBS9603615 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB; IHC | 0.1 mL | |
| MyBioSource | R247-177125-01 | MBS7136795 | DPP4, Recombinant Antibody | Rabbit | Monoclonal | Human | ELISA; IHC | 0.05 mL | |
| Biosynth | F502-104359-01 | 10R-3884 | DPP4 antibody | Mouse | Monoclonal | Human; Cross: Human | FC, IF, IHC, WB | 100 ul | |
| Biosynth | F502-119829-01 | 70R-16923 | DPP4 antibody | Rabbit | Polyclonal | Human; Cross: Human, Mouse, Rat | ELISA, IHC, WB | 50 ul | |
| MyBioSource | R247-125508-01 | MBS2007052 | Dipeptidyl Peptidase IV (DPP4), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Pig | ICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB | 0.1 mL | |
| MyBioSource | R247-150146-01 | MBS421335 | DPP4/CD26, Polyclonal Antibody | Goat | Polyclonal | Human, Mouse, Rat, Dog | EIA; WB | 0.1 mg | |
| MyBioSource | R247-156914-01 | MBS535458 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human | Immunohistochemistry (IHC) Paraffin | 0.05 mg | |
| MyBioSource | R247-134746-01 | MBS240136 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Bovine, Monkey | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-135138-01 | MBS244698 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Monkey | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-147518-01 | MBS3215964 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rat, Dog, Pig, Horse | WB | 0.1 mL | |
| MyBioSource | R247-169170-01 | MBS646929 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB | 0.2 mL | |
| MyBioSource | R247-135305-01 | MBS247512 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Monkey, Horse | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-191216-01 | MBS8242970 | CD26 (DPP4), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse | WB | 0.03 mL | |
| MyBioSource | R247-190668-01 | MBS8210799 | CD26 (DPP4), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB | 0.03 mL | |
| MyBioSource | R247-151391-01 | MBS438636 | CD26 (DPP4), Monoclonal Antibody | Mouse | Monoclonal | Human, Rat | FC/FACS; IF; IHC | 0.02 mg | |
| MyBioSource | R247-192151-01 | MBS830547 | DPP4, Monoclonal Antibody | Mouse | Monoclonal | Human | FC/FACS; IF; IHC; WB | 0.1 mL | |
| MyBioSource | R247-134747-01 | MBS240137 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rabbit, Monkey | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-113344-01 | MBS127123 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | WB; IF | 0.02 mL | |
| MyBioSource | R247-177709-01 | MBS714888 | dipeptidyl-peptidase 4 (DPP4), Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat | ELISA; WB; IHC | 0.1 mL | |
| MyBioSource | R247-135300-01 | MBS247427 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Rabbit, Bovine, Monkey, Pig, Horse | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-135070-01 | MBS244009 | DPP4 / CD26, Polyclonal Antibody | Rabbit | Polyclonal | Human, Bovine, Monkey, Pig, Sheep, Horse | Immunohistochemistry (IHC - Paraffin) | 0.05 mg | |
| MyBioSource | R247-156917-01 | MBS535489 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human | Immunohistochemistry (IHC) Paraffin | 0.05 mg | |
| MyBioSource | R247-147517-01 | MBS3215963 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human, Mouse, Rat, Rabbit, Dog, Pig, Horse | IHC; WB | 0.1 mL | |
| MyBioSource | R247-125116-01 | MBS2004294 | Dipeptidyl Peptidase IV (DPP4), Polyclonal Antibody | Rabbit | Polyclonal | Human, Bovine, Dog, Pig, Sheep, Goat | ICC; Immunohistochemistry (IHC) - Formalin/Paraffin; ELISA; WB | 0.1 mL | |
| MyBioSource | R247-168877-01 | MBS645545 | DPP4, Polyclonal Antibody | Rabbit | Polyclonal | Human | ELISA; WB | 0.2 mL | |
| ELK Biotechnology | T376-121559-01 | ES8387 | CD26 rabbit pAb | Rabbit | Polyclonal | Human;Rat;Mouse; | WB;IHC;IF;ELISA | 50μL | |
| MyBioSource | R247-193793-01 | MBS850046 | DPP4, Antibody | Rat | ELISA; WB | 0.05 mg | |||
| Biosynth | F502-109715-01 | 20R-DR024 | DPP4 antibody | Rabbit | Human; Cross: To be determined by end-user | IHC-P | 0.05 mg | ||
| Biosynth | F502-109714-01 | 20R-DR023 | DPP4 antibody | Rabbit | Human; Cross: To be determined by end-user | IHC-P | 0.05 mg |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
PAX6
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
FFAR1
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
GPR119
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
GIP
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
GATA4
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
ISL1
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
LEP
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
GCG
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)