DLL1 — 카탈로그 16건
Gene DLL1
NCBI Gene 28514
국내 소싱 가능
16건
유전자 개요
DLL1은 Notch Delta 리간드(ligand)의 인간 상동체(homolog)이며, 델타/세레이트/재그드(delta/serrate/jagged) 계열 단백질에 속한다. 이 유전자는 조혈 과정 중 세포 운명 결정에 관여하는 역할을 한다. 또한 세포 간 상호작용에도 관여할 수 있다.
Activated NOTCH1 Transmits Signal to the NucleusConstitutive Signaling by NOTCH1 HD Domain MutantsConstitutive Signaling by NOTCH1 HD+PEST Domain MutantsConstitutive Signaling by NOTCH1 PEST Domain MutantsConstitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation MutantDifferentiation of Keratinocytes in Interfollicular Epidermis in Mammalian SkinFormation of paraxial mesodermMECP2 regulates transcription of neuronal ligandsNOTCH2 Activation and Transmission of Signal to the NucleusNOTCH3 Activation and Transmission of Signal to the Nucleus
neurodevelopmental disorder with non-specific brain abnormalities and with or without seizurescancerhemoglobin measurementhematocriterythrocyte countgenetic disordermonocyte countneurodegenerative disease
데이터 출처 · 근거
- NCBI Gene ↗유전자 정보
- Open Targets ↗질환 연관·생물학적 경로
- 대표 논문 (PubMed) Precision medicine for human cancers with Notch signaling dysregulation (Review). · Int J Mol Med (2020)Mapping Development of the Human Intestinal Niche at Single-Cell Resolution. · Cell Stem Cell (2021)Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders. · Am J Hum Genet (2019)
체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.
| 견적 | 제조사 | Cat No | Mfr No | 제품명 | Host | Clonality | Reactivity | Application | Size |
|---|---|---|---|---|---|---|---|---|---|
| Biosynth | F502-124834-01 | 70R-21515 | DLL1 antibody | Rabbit | Polyclonal | Human; Cross: Human | ELISA, WB | 50 ul | |
| Cloud-Clone | T813-115537-01 | MAJ258Hu21 | Monoclonal Antibody to Delta Like Protein 1 (dLL1) | Mouse | Monoclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Cloud-Clone | T813-127579-01 | PAJ258Hu01 | Polyclonal Antibody to Delta Like Protein 1 (dLL1) | Rabbit | Polyclonal | Human | WB; IHC; ICC; IP. | 100µl | |
| Biosynth | F502-137322-01 | 70R-6123 | DLL1 antibody | Rabbit | Polyclonal | Human,Mouse,Rat | WB | 100 ul |
관련 표적
같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.
JAG1
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
ADAM10
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
JAG2
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
DLL4
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
NOTCH1
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
ADAM17
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
UBB
Constitutive Signaling by NOTCH1 HD Domain Mutants
HDAC1
MECP2 regulates transcription of neuronal ligands