해외 연구시약 수입·전문 취급 · 국내 대리점 관련 문의

DLD — 카탈로그 24건

Gene DLD NCBI Gene 1738
취급 제조사 5곳
CusabioMyBioSourceBiosynthCloud-CloneAbnova
국내 소싱 가능
24건

유전자 개요

DLD 유전자는 클래스-I 피리딘 뉴클레오티드-이황화물 산화 환원 효소(oxidoreductase) 계열의 구성원을 암호화한다. 이 유전자가 지정하는 단백질은 기작상 구별되는 여러 기능을 수행하는 능력 때문에 문라이트 단백질(moonlighting protein)로 확인되었다. 이 단백질은 이합체(homodimeric) 형태로 에너지 대사를 조절하는 여러 다중 효소 복합체(multi-enzyme complexes) 내에서 탈수소효소(dehydrogenase)로 기능한다. 하지만 단위체(monomer) 상태에서는 단백질분해효소(protease)로 작용할 수 있다. 이 유전자의 돌연변이는 E3 결핍성 단풍당밀뇨병 및 지질아미드 탈수소효소 결핍증 환자에게서 발견된다. 대립유전자 변이(alternative splicing)는 여러 전사체 변이를 일으킨다.

BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIVBranched-chain amino acid catabolismBranched-chain ketoacid dehydrogenase kinase deficiencyGlycine degradationH139Hfs13* PPM1K causes a mild variant of MSUDLoss-of-function mutations in DBT cause MSUD2Loss-of-function mutations in DLD cause MSUD3/DLDDMitochondrial protein degradationOADH complex synthesizes glutaryl-CoA from 2-OAOGDH complex synthesizes succinyl-CoA from 2-OG
pyruvate dehydrogenase E3 deficiencyLeigh syndromeinflammatory bowel diseaseneurodegenerative diseasegenetic disorderulcerative colitisisoleucine measurementvaline measurement
데이터 출처 · 근거

체크박스로 여러 제품을 선택해 한 번에 견적을 요청하세요. 제조사·Cat No·Application을 한 표에서 비교합니다.

견적제조사Cat NoMfr No제품명HostClonalityReactivityApplicationSize
CusabioT094-105646-01CSB-PA006928LA01HUDLD AntibodyRabbitPolyclonalHuman, Rat, MouseELISA, WB, IHC50μg, 100μg
MyBioSourceR247-213777-01MBS9607959DLD, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, RatWB; IHC; ELISA0.1 mL
BiosynthF502-104328-0110R-3838DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, WB100 ul
BiosynthF502-117328-0170R-14002DLD antibodyRabbitPolyclonalHumanWB, IHC-P, IHC-F, ICC0.1 mg
BiosynthF502-104330-0110R-3840DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, IF, IHC, WB100 ul
BiosynthF502-125365-0170R-2451DLD antibodyRabbitPolyclonalHuman, Rat; Cross: Predicted: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, ZebrafishWB100 ul
BiosynthF502-104327-0110R-3837DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, IF, IHC, WB100 ul
BiosynthF502-104325-0110R-3835DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, IF, IHC, WB100 ul
BiosynthF502-104329-0110R-3839DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, IF, WB100 ul
BiosynthF502-104326-0110R-3836DLD antibodyMouseMonoclonalHuman; Cross: HumanFC, WB100 ul
BiosynthF502-119746-0170R-16847DLD antibodyRabbitPolyclonalHuman; Cross: Human, Mouse, RatELISA, IHC, WB50 ul
Cloud-CloneT813-120118-01PAA919Hu01KO-Validated Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD)RabbitPolyclonalHumanWB; IHC; ICC/IF100µl
Cloud-CloneT813-120120-01PAA919Ra01Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD)RabbitPolyclonalRatWB; IHC100µl
Cloud-CloneT813-120119-01PAA919Mu01Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD)RabbitPolyclonalMurineWB; IHC100µl
Cloud-CloneT813-112670-01MAA919Hu22Monoclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD)MouseMonoclonalHumanWB; IHC; ICC; IP.100µl
MyBioSourceR247-147377-01MBS3213898DLD, Polyclonal AntibodyRabbitPolyclonalHuman, Mouse, Rat, Rabbit, Dog, Guinea Pig, Pig, Zebrafish, HorseIHC; WB0.1 mL

관련 표적

같은 생물학적 경로를 공유하는 표적 — 함께 검토되는 시약군입니다.

OGDH OGDH complex synthesizes succinyl-CoA from 2-OG PDHA1 PDH complex synthesizes acetyl-CoA from PYR PDHB PDH complex synthesizes acetyl-CoA from PYR DLAT PDH complex synthesizes acetyl-CoA from PYR BCKDK Branched-chain ketoacid dehydrogenase kinase deficiency PDK1 Regulation of pyruvate dehydrogenase (PDH) complex PDK2 Regulation of pyruvate dehydrogenase (PDH) complex PDK4 Regulation of pyruvate dehydrogenase (PDH) complex
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